A multidisciplinary team of clinicians, educators, and scientists working to improve the prevention and treatment of infectious diseases
August, 2023
June & July, 2023
May, 2023
April, 2023
Welcome to the Division of Infectious Diseases at the University of Colorado School of Medicine. This message is addressed to our colleagues, patients and members of the public with an interest in the problems and challenges of infectious diseases.
Our faculty, more than 70 and growing, take care of patients with infectious diseases in the mountain west and across the world, do scientific research on major infectious disease (ID) health problems, and educate the next generation of physicians and scientists in our field.
We work mainly at three sites located across the Denver metropolitan area:
1. The Anschutz Medical Campus (AMC). The AMC, which contains the School of Medicine (SOM) and is located in Aurora, just east of the Denver city line, was built to accommodate the growth of the SOM and fulfill its need for cutting edge facilities for research, education, and clinical missions. Many of the Infectious Diseases Division faculty are located physically in Research Complex 2 in the research quadrangle, where we have state of the art laboratories and bio-containment facilities for work with infectious agents. AMC ID physicians, physician assistants and nurse... practitioners take care of hospitalized patients in the University of Colorado Hospital (UCH). We take care of outpatients in our Infectious Disease Group Practice (IDGP) in the UCH outpatient pavilion.
2. Denver Health (DH). This municipal, integrated model public health care system serves a broad range of patients in Colorado, with education and research as two of its strategic pillars. DH is comprised of the Denver Health Medical Center (DHMC), a community health program with 8 centers and 16 school-based clinics in Denver, and the City and County health department (Denver Public Health, DPH). Infectious Diseases faculty are located in both DPH and the Department of Medicine of DHMC. Denver Public Health clinics include the ID Clinic and Center for Positive Health (HIV), the Denver Metro Tuberculosis (TB) Clinic serving the 7-county Metro area for diagnosis and treatment of TB and latent TB infection, and the Immunization and Travel Clinic (over 21,000 vaccinations to 10,000 patients per year). DHMC, in partnership with the Colorado Department of Health and Environment, is one of nine designated regional Ebola and other special pathogen treatment centers in the U.S.
Photo panel of the faculty members of the CU Division of Infectious Diseases
Quiros-Gomez O, Segura-Cardona Á, Flórez PA, et al. Risk factors and spatial analysis for domiciliary infestation with the Chagas disease vector Triatoma venosa in Colombia. Ther Adv Infect Dis. 2022;9:20499361221084164. doi:10.1177/20499361221084164
Frost HM, Sebastian T, Keith A, et al. COVID-19 and Acute Otitis Media in Children: A Case Series. J Prim Care Community Health. 2022;13:21501319221082350. doi:10.1177/21501319221082351
Dillon SM, Mickens KL, Thompson TA, et al. Granzyme B(+) CD4 T cells accumulate in the colon during chronic HIV-1 infection. Gut Microbes. 2022;14(1):2045852. doi:10.1080/19490976.2022.2045852
Chastain DB, Osae SP, Thomas GM, et al. Clinical Severity on Hospital Admission for COVID-19: An Analysis of Social Determinants of Health From an Early Hot Spot in the Southeastern U.S. J Prim Care Community Health. 2022;13:21501319221092244. doi:10.1177/21501319221092244
Chastain DB, Henao-Martínez AF, Dykes AC, et al. Missed opportunities to identify cryptococcosis in COVID-19 patients: a case report and literature review. Ther Adv Infect Dis. 2022;9:20499361211066364. doi:10.1177/20499361211066363
Castleman MJ, Stumpf MM, Therrien NR, et al. SARS-CoV-2 infection relaxes peripheral B cell tolerance. J Exp Med. 2022;219(6):e20212553. doi:10.1084/jem.20212553
Higuita NA, Suarez JA, Millender E, et al. U.S. bound journey of migrant peoples InTransit across Dante’s Inferno and Purgatory in the Americas. Travel Med Infect Dis. 2022;47:102317. doi:10.1016/j.tmaid.2022.102317
Ballandras-Colas A, Chivukula V, Gruszka DT, et al. Multivalent interactions essential for lentiviral integrase function. Nat Commun. 2022;13(1):2416. doi:10.1038/s41467-022-29928-8
McWhirter L, Lou Y, Reingold S, et al. Rates of Appropriate Treatment and Follow-Up Testing After a Gonorrhea and/or Chlamydia Infection in an Urban Network of Federally Qualified Health Center Systems. Sex Transm Dis. 2022;49(5):319-324. doi:10.1097/OLQ.0000000000001600
Pandey S, Hu Y, Bushman LR, Castillo-Mancilla J, Anderson PL, Cooks RG. Miniature mass spectrometer-based point-of-care assay for cabotegravir and rilpivirine in whole blood. Anal Bioanal Chem. 2022;414(11):3387-3395. doi:10.1007/s00216-022-03954-3
Hoover RK, Krsak M, Molina KC, Shah K, Redell M. Kimyrsa, An Oritavancin-Containing Product: Clinical Study and Review of Properties. Open Forum Infect Dis. 2022;9(5):ofac090. doi:10.1093/ofid/ofac090
Castillo-Mancilla JR, Musinguzi N, Asiimwe S, et al. High residual inflammation despite HIV viral suppression: Lessons learned from real-time adherence monitoring among people with HIV in Africa. HIV Med. 2022;23(5):465-473. doi:10.1111/hiv.13200
Brooks KM, Castillo-Mancilla JR, Morrow M, et al. Predictors of 007 triphosphate concentrations in dried blood spots in persons with hepatitis C and active drug or alcohol use. J Antimicrob Chemother. 2022;77(5):1396-1403. doi:10.1093/jac/dkac051
Haukoos JS, Rowan SE, Galbraith JW, et al. The Determining Effective Testing in Emergency Departments and Care Coordination on Treatment Outcomes (DETECT) for Hepatitis C (Hep C) Screening Trial: rationale and design of a multi-center pragmatic randomized clinical trial of hepatitis C screening in emergency departments. Trials. 2022;23(1):354. doi:10.1186/s13063-022-06265-1
Bowman ER, Wilson M, Riedl KM, et al. Lipidome Alterations with Exercise Among People With and Without HIV: An Exploratory Study. AIDS Res Hum Retroviruses. Published online April 21, 2022. doi:10.1089/AID.2021.0154
Bai X, Buckle AM, Vladar EK, et al. Author Correction: Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19. Sci Rep. 2022;12(1):6466. doi:10.1038/s41598-022-10890-w
Cook P, Jankowski C, Erlandson KM, Reeder B, Starr W, Flynn Makic MB. Low- and High-Intensity Physical Activity Among People with HIV: Multilevel Modeling Analysis Using Sensor- and Survey-Based Predictors. JMIR Mhealth Uhealth. 2022;10(4):e33938. doi:10.2196/33938
Bago B, Kovacs M, Protzko J, et al. Situational factors shape moral judgements in the trolley dilemma in Eastern, Southern and Western countries in a culturally diverse sample. Nat Hum Behav. Published online April 14, 2022. doi:10.1038/s41562-022-01319-5
Beatty NL, Forsyth CJ, Gilman RH, et al. Neglected Testing for Neglected Tropical Diseases at the CDC. Am J Trop Med Hyg. Published online April 12, 2022:tpmd220222. doi:10.4269/ajtmh.22-0222
Oliveira VHF, Erlandson KM, Cook PF, et al. The High-Intensity Exercise Study to Attenuate Limitations and Train Habits in Older Adults With HIV (HEALTH): A Research Protocol. J Assoc Nurses AIDS Care. 2022;33(2):178-188. doi:10.1097/JNC.0000000000000276
Masters MC, Yang J, Lake JE, et al. Diabetes mellitus is associated with declines in physical function among men with and without HIV. AIDS. 2022;36(5):637-646. doi:10.1097/QAD.0000000000003160
Hauschild BC, Burnside HC, Gray BA, et al. Characteristics of the Audience Reached by the National Network of Sexually Transmitted Disease Clinical Prevention Training Centers and Correlation With Sexually Transmitted Infection Rates, 2015 to 2020. Sex Transm Dis. 2022;49(4):313-317. doi:10.1097/OLQ.0000000000001590
Deminice R, Oliveira VHF, Webel AR, Erlandson KM. Sarcopenia Related to Human Immunodeficiency Virus: Protective Effects of Exercise. Exerc Sport Sci Rev. 2022;50(2):73-80. doi:10.1249/JES.0000000000000282
Barr EA, Raybin JL, Dunlevy H, Abuogi L, Jones J. Transition From Pediatric and Adolescent HIV Care to Adult HIV Care and the Patient-Provider Relationship: A Qualitative Metasynthesis. J Assoc Nurses AIDS Care. 2022;33(2):132-154. doi:10.1097/JNC.0000000000000239
Solomon SS, Wagner-Cardoso S, Smeaton L, et al. A minimal monitoring approach for the treatment of hepatitis C virus infection (ACTG A5360 [MINMON]): a phase 4, open-label, single-arm trial. Lancet Gastroenterol Hepatol. 2022;7(4):307-317. doi:10.1016/S2468-1253(21)00397-6
Nakayama T, Lee IT, Le W, et al. Inflammatory molecular endotypes of nasal polyps derived from White and Japanese populations. J Allergy Clin Immunol. 2022;149(4):1296-1308.e6. doi:10.1016/j.jaci.2021.11.017
Molina KC, Bajrovic V, Bonomo RA. Carbapenemase-producing Enterobacterales in solid organ transplantation: Tip of the iceberg? Transpl Infect Dis. 2022;24(2):e13780. doi:10.1111/tid.13780
Miller EK, Goldberg AM, Janoff EN, et al. Designing and implementing methodology for double-blind, placebo-controlled clinical trials using blood products within the Department of Veterans Affairs. Clin Trials. 2022;19(2):137-145. doi:10.1177/17407745211069703
Goodman A, Patten L, Castillo-Mancilla J, Zimmer S, Madinger N, Frasca K. Factors Associated with Retention and Adherence in a Comprehensive, Diverse HIV Pre-Exposure Prophylaxis Clinic. AIDS Res Hum Retroviruses. 2022;38(4):327-335. doi:10.1089/AID.2021.0130
de Graaf DM, Teufel LU, Joosten LAB, Dinarello CA. Interleukin-38 in Health and Disease. Cytokine. 2022;152:155824. doi:10.1016/j.cyto.2022.155824
Aronsohn AI, Bhattacharya D, Morgan TR, Wyles DL, Chung RT, McQuillen DP. Reply. Hepatology. 2022;75(4):1055-1056. doi:10.1002/hep.32257
Capin JJ, Wilson MP, Hare K, et al. Prospective telehealth analysis of functional performance, frailty, quality of life, and mental health after COVID-19 hospitalization. BMC Geriatr. 2022;22(1):251. doi:10.1186/s12877-022-02854-6
Psomas CK, Hoover DR, Shi Q, et al. POLYPHARMACY IS ASSOCIATED WITH FALLS IN WOMEN WITH AND WITHOUT HIV. J Acquir Immune Defic Syndr. Published online March 25, 2022. doi:10.1097/QAI.0000000000002955
Bai X, Buckle AM, Vladar EK, et al. Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19. Sci Rep. 2022;12(1):5207. doi:10.1038/s41598-022-09133-9
Davis AJ, Greene M, Siegler E, et al. Strengths and Challenges of Various Models of Geriatric Consultation for Older Adults Living With Human Immunodeficiency Virus. Clin Infect Dis. 2022;74(6):1101-1106. doi:10.1093/cid/ciab682
Wilkin T, Chen H, Sahasrabuddhe V, et al. A randomized clinical trial of HPV test-and-treat as compared to cytology-based screening for prevention of cervical cancer among women living with HIV: AIDS Clinical Trials Group Protocol A5282. Clin Infect Dis. Published online March 16, 2022:ciac213. doi:10.1093/cid/ciac213
Galbraith MD, Kinning KT, Sullivan KD, et al. Specialized interferon action in COVID-19. Proc Natl Acad Sci U S A. 2022;119(11). doi:10.1073/pnas.2116730119
O’Brien KK, Brown DA, Bergin C, et al. Long COVID and episodic disability: advancing the conceptualisation, measurement and knowledge of episodic disability among people living with Long COVID - protocol for a mixed-methods study. BMJ Open. 2022;12(3):e060826. doi:10.1136/bmjopen-2022-060826
Diaz Del Valle F, Zakrajsek JK, Min SJ, et al. Impact of Airline Secondhand Tobacco Smoke Exposure on Respiratory Health and Lung Function Decades After Exposure Cessation. Chest. Published online March 7, 2022:S0012-3692(22)00416-0. doi:10.1016/j.chest.2022.02.049
Looby SE, Kantor A, Burdo TH, et al. Factors Associated with Systemic Immune Activation Indices in a Global Primary Cardiovascular Disease Prevention Cohort of People with HIV on Antiretroviral Therapy. Clin Infect Dis. Published online March 2, 2022:ciac166. doi:10.1093/cid/ciac166
Gorse GJ, Rattigan SM, Kirpich A, et al. Influence of Preseason Antibodies Against Influenza Virus on Risk of Influenza Infection Among Healthcare Personnel. J Infect Dis. 2022;225(5):891-902. doi:10.1093/infdis/jiab468
Abuogi LL, Castillo-Mancilla J, Hampanda K, et al. Tenofovir Diphosphate in Dried Blood Spots in Pregnant and Postpartum Women With HIV in Kenya: A Novel Approach to Measuring Peripartum Adherence. J Acquir Immune Defic Syndr. 2022;89(3):310-317. doi:10.1097/QAI.0000000000002859
Smith L, Letendre S, Erlandson KM, Ma Q, Ellis RJ, Farhadian SF. Polypharmacy in older adults with HIV infection: Effects on the brain. J Am Geriatr Soc. 2022;70(3):924-927. doi:10.1111/jgs.17569
Schröder A, Lunding LP, Zissler UM, et al. IL-37 regulates allergic inflammation by counterbalancing pro-inflammatory IL-1 and IL-33. Allergy. 2022;77(3):856-869. doi:10.1111/all.15072
Satyanarayana G, Enriquez KT, Sun T, et al. Coinfections in Patients With Cancer and COVID-19: A COVID-19 and Cancer Consortium (CCC19) Study. Open Forum Infect Dis. 2022;9(3):ofac037. doi:10.1093/ofid/ofac037
Molina KC, Miller MA, Mueller SW, Van Matre ET, Krsak M, Kiser TH. Clinical Pharmacokinetics and Pharmacodynamics of Dalbavancin. Clin Pharmacokinet. 2022;61(3):363-374. doi:10.1007/s40262-021-01088-w
Lunding LP, Skouras DB, Vock C, Dinarello CA, Wegmann M. The NLRP3 inflammasome inhibitor, OLT1177(®) , ameliorates experimental allergic asthma in mice. Allergy. 2022;77(3):1035-1038. doi:10.1111/all.15164
Freddo AM, Mathur S, Dunlevy H, Jaggers J, Khanna A. Endocarditis Caused by Candida parapsilosis Presenting With Severe Thrombocytopenia in a Patient With Tetralogy of Fallot. World J Pediatr Congenit Heart Surg. 2022;13(2):245-247. doi:10.1177/21501351211008839
Winglee K, Hill AN, Belknap R, Stout JE, Ayers TL. Variability of interferon-γ release assays in people at high risk of tuberculosis infection or progression to tuberculosis disease living in the United States. Clin Microbiol Infect. Published online February 18, 2022:S1198-743X(22)00094-5. doi:10.1016/j.cmi.2022.02.020
Montague BT, Wipperman MF, Hooper AT, et al. Anti-SARS-CoV-2 IgA Identifies Asymptomatic Infection in First Responders. J Infect Dis. 2022;225(4):578-586. doi:10.1093/infdis/jiab524
Jennings L, Robbins RN, Nguyen N, et al. Tenofovir diphosphate in dried blood spots predicts future viremia in persons with HIV taking antiretroviral therapy in south africa. AIDS. Published online February 15, 2022. doi:10.1097/QAD.0000000000003185
Erlandson KM, Fitch KV, McCallum SA, et al. Geographical Differences in the Self-Reported Functional Impairment of People with HIV and Associations with Cardiometabolic Risk. Clin Infect Dis. Published online February 15, 2022:ciac098. doi:10.1093/cid/ciac098
Adu-Ampratwum D, Pan Y, Koneru PC, et al. Identification and Optimization of a Novel HIV-1 Integrase Inhibitor. ACS Omega. 2022;7(5):4482-4491. doi:10.1021/acsomega.1c06378
Hoke KL, Zimmer SL, Roddy AB, Ondrechen MJ, Williamson CE, Buan NR. Reintegrating Biology Through the Nexus of Energy, Information, and Matter. Integr Comp Biol. 2022;61(6):2082-2094. doi:10.1093/icb/icab174
Chastain DB, Rao A, Yaseyyedi A, Henao-Martínez AF, Borges T, Franco-Paredes C. Cerebral Cryptococcomas: A Systematic Scoping Review of Available Evidence to Facilitate Diagnosis and Treatment. Pathogens. 2022;11(2). doi:10.3390/pathogens11020205
Abdo M, Wu X, Sharma A, et al. Regional Differences in Risk of Recurrent Falls Among Older U.S. Women and Men with HIV in the HIV Infection, Aging, and Immune Function Long-Term Observational Study. AIDS Res Hum Retroviruses. Published online February 2, 2022. doi:10.1089/AID.2021.0162
Ren DM, Abrams A, Banigan M, et al. Evaluation of Communication and Safety Behaviors During Hospital-Wide Code Response Simulation. Simul Healthc. 2022;17(1):e45-e50. doi:10.1097/SIH.0000000000000575
Ortiz-Martínez Y, Rodríguez-Morales AJ, Henao-Martínez AF. Decreased notification of TB cases during the COVID-19 pandemic. Int J Tuberc Lung Dis. 2022;26(2):177-178. doi:10.5588/ijtld.21.0651
Dhindsa S, Ghanim H, Jenkins T, et al. High prevalence of subnormal testosterone in obese adolescent males: reversal with bariatric surgery. Eur J Endocrinol. 2022;186(3):319-327. doi:10.1530/EJE-21-0545
Chai PR, Mohamed Y, Bustamante MJ, et al. DigiPrEP: A Pilot Trial to Evaluate the Feasibility, Acceptability, and Accuracy of a Digital Pill System to Measure PrEP Adherence in Men Who Have Sex With Men Who Use Substances. J Acquir Immune Defic Syndr. 2022;89(2):e5-e15. doi:10.1097/QAI.0000000000002854
Teufel LU, Arts RJW, Netea MG, Dinarello CA, Joosten LAB. IL-1 family cytokines as drivers and inhibitors of trained immunity. Cytokine. 2022;150:155773. doi:10.1016/j.cyto.2021.155773
Summer SS, Jenkins T, Inge T, Deka R, Khoury JC. Association of diet quality, physical activity, and abdominal obesity with metabolic syndrome z-score in black and white adolescents in the US. Nutr Metab Cardiovasc Dis. 2022;32(2):346-354. doi:10.1016/j.numecd.2021.10.021
Novak AR, Krsak M, Kiser TH, et al. Pharmacokinetic Evaluation of Cefazolin in the Cerebrospinal Fluid of Critically Ill Patients. Open Forum Infect Dis. 2022;9(2):ofab649. doi:10.1093/ofid/ofab649
Lundgren JD, Grund B, Barkauskas CE, et al. Responses to a Neutralizing Monoclonal Antibody for Hospitalized Patients With COVID-19 According to Baseline Antibody and Antigen Levels : A Randomized Controlled Trial. Ann Intern Med. 2022;175(2):234-243. doi:10.7326/M21-3507
Kamis KF, Wyles DL, Minturn MS, et al. Hepatitis C Testing and Linkage to Care Among Adults on Probation in a Large US City. Open Forum Infect Dis. 2022;9(2):ofab636. doi:10.1093/ofid/ofab636
Jolley S, Nordon-Craft A, Wilson MP, et al. Disparities in the allocation of inpatient physical and occupational therapy services for patients with COVID-19. J Hosp Med. 2022;17(2):88-95. doi:10.1002/jhm.12785
Frost HM, Munsiff SS, Lou Y, Jenkins TC. Simplifying outpatient antibiotic stewardship. Infect Control Hosp Epidemiol. 2022;43(2):260-261. doi:10.1017/ice.2020.1409
Frank DN, Qiu Y, Cao Y, et al. A dysbiotic microbiome promotes head and neck squamous cell carcinoma. Oncogene. 2022;41(9):1269-1280. doi:10.1038/s41388-021-02137-1
van de Veerdonk FL, Renga G, Pariano M, et al. Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy. J Clin Invest. 2022;132(2). doi:10.1172/JCI144983
Rowan SE, McCormick DW, Wendel KA, et al. Lower Prevalence of SARS-CoV-2 Infection Among People Experiencing Homelessness Tested in Outdoor Encampments Compared with Overnight Shelters - Denver, Colorado, June - July 2020. Clin Infect Dis. Published online January 18, 2022. doi:10.1093/cid/ciac039
Barrett B, Nguyen DH, Xu J, et al. SAMHD1 Promotes the Antiretroviral Adaptive Immune Response in Mice Exposed to Lipopolysaccharide. J Immunol. 2022;208(2):444-453. doi:10.4049/jimmunol.2001389
Brijkumar J, Edwards JA, Johnson BA, et al. Comparing effectiveness of first-line antiretroviral therapy between peri-urban and rural clinics in KwaZulu-Natal, South Africa. HIV Med. Published online January 12, 2022. doi:10.1111/hiv.13231
Dyamenahalli K, Choy K, Frank DN, et al. Age and injury size influence the magnitude of fecal dysbiosis in adult burn patients. J Burn Care Res. Published online January 10, 2022:irac001. doi:10.1093/jbcr/irac001
Windsor WJ, Knight V, Merkel PA, et al. COVID-19 Serology Control Panel Using the Dried-Tube Specimen Method. Am J Trop Med Hyg. 2022;106(2):562-565. doi:10.4269/ajtmh.21-1036
Odayar J, Orrell C, Phillips TK, et al. Use of tenofovir diphosphate levels to predict viremia during the postpartum period in women living with HIV: a nested case-control study. Clin Infect Dis. Published online January 3, 2022:ciab1068. doi:10.1093/cid/ciab1068
Windham S, Hirsch K, Peterson R, et al. The Predictive Potential of Elevated Serum Inflammatory Markers in Determining the Need for Intubation in CoVID-19 Patients. J Crit Care Med (Targu Mures). 2022;8(1):14-22. doi:10.2478/jccm-2021-0035
Wandling M, Cuschieri J, Kozar R, et al. Multi-center validation of the Bowel Injury Predictive Score (BIPS) for the early identification of need to operate in blunt bowel and mesenteric injuries. Injury. 2022;53(1):122-128. doi:10.1016/j.injury.2021.07.026
Shepard Z, Skorupa T, Espinoza L, Erlandson K, Damioli L. Coxiella burnetii Infection Associated With Thromboangiitis Obliterans-like Phenomena With Digital Autoamputation: A Case Report and Review of Q Fever-Associated Autoimmunity. Open Forum Infect Dis. 2022;9(1):ofab637. doi:10.1093/ofid/ofab637
Haukoos JS, White DAE, Rowan SE, et al. Development of a 2-step algorithm to identify emergency department patients for HIV pre-exposure prophylaxis. Am J Emerg Med. 2022;51:6-12. doi:10.1016/j.ajem.2021.09.084
Frost HM, Lou Y, Keith A, Byars A, Jenkins TC. Increasing Guideline-Concordant Durations of Antibiotic Therapy for Acute Otitis Media. J Pediatr. 2022;240:221-227.e9. doi:10.1016/j.jpeds.2021.07.016
Franco-Paredes C. Transmissibility of SARS-CoV-2 among fully vaccinated individuals. Lancet Infect Dis. 2022;22(1):16. doi:10.1016/S1473-3099(21)00768-4
Embi PJ, Levy ME, Naleway AL, et al. Effectiveness of two-dose vaccination with mRNA COVID-19 vaccines against COVID-19-associated hospitalizations among immunocompromised adults-Nine States, January-September 2021. Am J Transplant. 2022;22(1):306-314. doi:10.1111/ajt.16641
Amo-Aparicio J, Garcia-Garcia J, Puigdomenech M, et al. Inhibition of the NLRP3 inflammasome by OLT1177 induces functional protection and myelin preservation after spinal cord injury. Exp Neurol. 2022;347:113889. doi:10.1016/j.expneurol.2021.113889
Vicente-Alcalde N, Ruescas-Escolano E, Franco-Paredes C, Tuells J. Control of a COVID-19 Outbreak in a Spanish Prison: Lessons Learned in Outbreak Control. Front Med (Lausanne). 2022;9:806438. doi:10.3389/fmed.2022.806438
McMahan RH, Hulsebus HJ, Najarro KM, et al. Age-Related Intestinal Dysbiosis and Enrichment of Gut-specific Bacteria in the Lung Are Associated With Increased Susceptibility to Streptococcus pneumoniae Infection in Mice. Front Aging. 2022;3:859991. doi:10.3389/fragi.2022.859991
Guo K, Barrett BS, Mickens KL, et al. Interferon Resistance of Emerging SARS-CoV-2 Variants. bioRxiv. Published online December 10, 2021:2021.03.20.436257. doi:10.1101/2021.03.20.436257
Kates OS, Haydel BM, Florman SS, et al. Coronavirus Disease 2019 in Solid Organ Transplant: A Multicenter Cohort Study. Clin Infect Dis. 2021;73(11):e4090-e4099. doi:10.1093/cid/ciaa1097
Cummings DAT, Radonovich LJ, Gorse GJ, et al. Risk Factors for Healthcare Personnel Infection With Endemic Coronaviruses (HKU1, OC43, NL63, 229E): Results from the Respiratory Protection Effectiveness Clinical Trial (ResPECT). Clin Infect Dis. 2021;73(11):e4428-e4432. doi:10.1093/cid/ciaa900
Yager JL, Brooks KM, Castillo-Mancilla JR, et al. Tenofovir-diphosphate in peripheral blood mononuclear cells during low, medium and high adherence to emtricitabine/ tenofovir alafenamide vs. emtricitabine/ tenofovir disoproxil fumarate. AIDS. 2021;35(15):2481-2487. doi:10.1097/QAD.0000000000003062
Wendel KA, Mauk K, Amsterdam L, et al. Enhancing Gonococcal Antimicrobial Resistance Surveillance in Cisgender Women, Strengthening the US Response to Resistant Gonorrhea, 2018 to 2019. Sex Transm Dis. 2021;48(12S Suppl 2):S104-S110. doi:10.1097/OLQ.0000000000001554
Schlanger K, Learner ER, Pham CD, et al. Strengthening the US Response to Resistant Gonorrhea: An Overview of a Multisite Program to Enhance Local Response Capacity for Antibiotic-Resistant Neisseria gonorrhoeae. Sex Transm Dis. 2021;48(12S Suppl 2):S97-S103. doi:10.1097/OLQ.0000000000001545
Rietmeijer CA, Hauschild BC, Burnside HC, Wendel KA. Medicaid Expansion and Rates of Reportable Sexually Transmitted Infections in the United States: A County-Level Analysis. Sex Transm Dis. 2021;48(12):e190-e191. doi:10.1097/OLQ.0000000000001422
Maragh-Bass AC, Parker S, Thompson G, et al. “Ending the HIV epidemic”: where are African American women in the plan? AIDS. 2021;35(15):2541-2544. doi:10.1097/QAD.0000000000003037
Kousari A, Moser C, Olefsky M, et al. Poorer Muscle Quality and Quantity With ART Initiation Is Associated With Greater Inflammation and Immune Activation. J Acquir Immune Defic Syndr. 2021;88(4):399-405. doi:10.1097/QAI.0000000000002776
Wyles DL, Kang M, Matining RM, Murphy RL, Peters MG. Continued Low Rates of Hepatitis C Virus (HCV) Recurrence in HCV/HIV- and HCV-Infected Participants Who Achieved Sustained Virologic Response After Direct-Acting Antiviral Treatment: Final Results From the AIDS Clinical Trials Group A5320 Viral Hepatitis C Infection Long-term Cohort Study (V-HICS). Open Forum Infect Dis. 2021;8(12):ofab511. doi:10.1093/ofid/ofab511
Windham S, Wilson MP, Fling C, et al. Elevated glycohemoglobin is linked to critical illness in CoVID-19: a retrospective analysis. Ther Adv Infect Dis. 2021;8:20499361211027390. doi:10.1177/20499361211027390
Viszlayová D, Sojka M, Dobrodenková S, et al. SARS-CoV-2 RNA in the Cerebrospinal Fluid of a Patient with Long COVID. Ther Adv Infect Dis. 2021;8:20499361211048572. doi:10.1177/20499361211048572
Semitala FC, Kadota JL, Musinguzi A, et al. Completion of isoniazid-rifapentine (3HP) for tuberculosis prevention among people living with HIV: Interim analysis of a hybrid type 3 effectiveness-implementation randomized trial. PLoS Med. 2021;18(12):e1003875. doi:10.1371/journal.pmed.1003875
Rosolanka R, Henao-Martinez AF, Pisney L, Franco-Paredes C, Krsak M. COVID-19: a review of current knowledge regarding exposure, quarantine, isolation and other preventive measures. Ther Adv Infect Dis. 2021;8:20499361211032040. doi:10.1177/20499361211032039
Rodriguez-Morales AJ, Sah R, Millan-Oñate J, et al. COVID-19 associated mucormycosis: the urgent need to reconsider the indiscriminate use of immunosuppressive drugs. Ther Adv Infect Dis. 2021;8:20499361211027064. doi:10.1177/20499361211027065
Rodríguez-Morales AJ, Bonilla-Aldana DK, Suárez JA, et al. Yellow fever reemergence in Venezuela - Implications for international travelers and Latin American countries during the COVID-19 pandemic. Travel Med Infect Dis. 2021;44:102192. doi:10.1016/j.tmaid.2021.102192
Quan NG, Latif H, Krsak M, et al. Benefits of COVID-19 viral screening of formerly incarcerated individuals during community reentry. Ther Adv Infect Dis. 2021;8:2049936120985951. doi:10.1177/2049936120985951
Marcus R, Henao-Martínez AF, Nolan M, et al. Recognition and screening for Chagas disease in the USA. Ther Adv Infect Dis. 2021;8:20499361211046090. doi:10.1177/20499361211046086
Kristofich M, Anderson PL, Castillo-Mancilla JR. Beyond HIV viral load: application of pharmacologic measures to identify ART adherence mismatch. Ther Adv Infect Dis. 2021;8:20499361211010596. doi:10.1177/20499361211010596
Kalil AC, Mehta AK, Patterson TF, et al. Efficacy of interferon beta-1a plus remdesivir compared with remdesivir alone in hospitalised adults with COVID-19: a double-bind, randomised, placebo-controlled, phase 3 trial. Lancet Respir Med. 2021;9(12):1365-1376. doi:10.1016/S2213-2600(21)00384-2
Gharamti AA, Mundo W, Chastain DB, Franco-Paredes C, Henao-Martínez AF, Shapiro L. Pneumocystis jirovecii pneumonia: a proposed novel model of corticosteroid benefit. Ther Adv Infect Dis. 2021;8:20499361211032030. doi:10.1177/20499361211032034
García Oronoz G, Pedraza-Arévalo LC, Henao-Martínez AF, Franco-Paredes C, Suarez JA. Visceral leishmaniasis in the island of Margarita, Venezuela: a neglected parasitic infection in the Caribbean. Ther Adv Infect Dis. 2021;8:20499361211031710. doi:10.1177/20499361211031714
Gabster A, Jhangimal M, Erausquin JT, et al. Rapid health evaluation in migrant peoples in transit through Darien, Panama: protocol for a multimethod qualitative and quantitative study. Ther Adv Infect Dis. 2021;8:20499361211066190. doi:10.1177/20499361211066190
Frost HM, Sebastian T, Durfee J, Jenkins TC. Ophthalmic antibiotic use for acute infectious conjunctivitis in children. J AAPOS. 2021;25(6):350.e1-350.e7. doi:10.1016/j.jaapos.2021.06.006
Erlandson KM, Liu J, Johnson R, et al. An exercise intervention alters stool microbiota and metabolites among older, sedentary adults. Ther Adv Infect Dis. 2021;8:20499361211027068. doi:10.1177/20499361211027067
Chadalawada S, Rassi AJ, Samara O, et al. Mortality risk in chronic Chagas cardiomyopathy: a systematic review and meta-analysis. ESC Heart Fail. 2021;8(6):5466-5481. doi:10.1002/ehf2.13648
Castillo-Mancilla JR, Edwards JA, Brijkumar J, et al. Tenofovir diphosphate levels in dried blood spots are associated with virologic failure and resistance to first-line therapy in South Africa: a case-control cohort study. J Int AIDS Soc. 2021;24(12):e25849. doi:10.1002/jia2.25849
Archuleta S, Gharamti AA, Sillau S, et al. Increased mortality associated with uncontrolled diabetes mellitus in patients with pulmonary cryptococcosis: a single US cohort study. Ther Adv Infect Dis. 2021;8:20499361211004370. doi:10.1177/20499361211004367
Agudelo-Higuita NI, Rodriguez-Morales AJ, Henao-Martinez AF, Franco-Paredes C, Gabster A. The treacherous journey of hundreds of migrants from Cameroon to reach the United States. Travel Med Infect Dis. 2021;44:102172. doi:10.1016/j.tmaid.2021.102172
Agudelo Higuita NI, White BP, Franco-Paredes C, McGhee MA. An update on prevention of malaria in travelers. Ther Adv Infect Dis. 2021;8:20499361211040690. doi:10.1177/20499361211040690
Naranjo L, Carrillo-Villaseñor F, D’Suze G, et al. Ischemic Stroke in a Child after a Probable Scorpion Sting. Am J Trop Med Hyg. 2021;106(3):959-961. doi:10.4269/ajtmh.21-0880
Liu S, Koneru PC, Li W, et al. HIV-1 integrase binding to genomic RNA 5’-UTR induces local structural changes in vitro and in virio. Retrovirology. 2021;18(1):37. doi:10.1186/s12977-021-00582-0
O’Brien KK, Bayoumi AM, Chan Carusone S, et al. Disability and self-care living strategies among adults living with HIV during the COVID-19 pandemic. AIDS Res Ther. 2021;18(1):87. doi:10.1186/s12981-021-00413-4
Radtke KK, Ernest JP, Zhang N, et al. Comparative Efficacy of Rifapentine Alone and in Combination with Isoniazid for Latent Tuberculosis Infection: a Translational Pharmacokinetic-Pharmacodynamic Modeling Study. Antimicrob Agents Chemother. 2021;65(12):e0170521. doi:10.1128/AAC.01705-21
Sulkowski M, Wyles D. Déjà vu All Over Again: Retreatment of HCV Direct Acting Antivirals Failures-Same Satisfactory Results, Same Unanswered Questions. Clin Infect Dis. 2021;73(9):e3296-e3299. doi:10.1093/cid/ciaa1329
Haas MK, Aiona K, Erlandson KM, Belknap RW. Higher Completion Rates With Self-administered Once-weekly Isoniazid-rifapentine Versus Daily Rifampin in Adults With Latent Tuberculosis. Clin Infect Dis. 2021;73(9):e3459-e3467. doi:10.1093/cid/ciaa1364
Kamis KF, Barbera L, Abdo M, et al. Risk Factors for Hospitalization in People With HIV and COVID-19. J Acquir Immune Defic Syndr. 2021;88(3):e22. doi:10.1097/QAI.0000000000002780
Quandelacy TM, Zimmer S, Lessler J, et al. Predicting virologically confirmed influenza using school absences in Allegheny County, Pennsylvania, USA during the 2007-2015 influenza seasons. Influenza Other Respir Viruses. 2021;15(6):757-766. doi:10.1111/irv.12865
Krsak M, Harry BL, Palmer BE, Franco-Paredes C. Response to Mishra et al. re “Postinfectious Immunity After COVID-19 and Vaccination Against SARS-CoV-2”. Viral Immunol. 2021;34(9):659-660. doi:10.1089/vim.2021.0147
Kamkwalala AR, Garg A, Roy U, et al. Current Considerations for Clinical Management and Care of People with HIV: Findings from the 11th Annual International HIV and Aging Workshop. AIDS Res Hum Retroviruses. 2021;37(11):807-820. doi:10.1089/AID.2021.0059
Hirsch SD, Elling CL, Bootpetch TC, et al. The role of CDHR3 in susceptibility to otitis media. J Mol Med (Berl). 2021;99(11):1571-1583. doi:10.1007/s00109-021-02118-7
Hernández-Favela CG, Hernández-Ruiz VA, Bello-Chavolla OY, et al. Higher Veterans Aging Cohort Study 2.0 Index Score Predicts Functional Decline Among Older Adults Living with HIV. AIDS Res Hum Retroviruses. 2021;37(11):878-883. doi:10.1089/AID.2020.0295
de Graaf DM, Teufel LU, van de Veerdonk FL, et al. IL-38 prevents induction of trained immunity by inhibition of mTOR signaling. J Leukoc Biol. 2021;110(5):907-915. doi:10.1002/JLB.3A0220-143RRR
Cooper MM, Preslaski CR, Shihadeh KC, Hawkins KL, Jenkins TC. Multiple-Dose Dalbavancin Regimens as the Predominant Treatment of Deep-Seated or Endovascular Infections: A Scoping Review. Open Forum Infect Dis. 2021;8(11):ofab486. doi:10.1093/ofid/ofab486
Carriger JF, Thompson M, Barron MG. Causal Bayesian networks in assessments of wildfire risks: Opportunities for ecological risk assessment and management. Integr Environ Assess Manag. 2021;17(6):1168-1178. doi:10.1002/ieam.4443
Campbell TW, Wilson MP, Roder H, et al. Predicting prognosis in COVID-19 patients using machine learning and readily available clinical data. Int J Med Inform. 2021;155:104594. doi:10.1016/j.ijmedinf.2021.104594
Bessesen MT, Rattigan S, Frederick J, et al. Outpatient healthcare personnel knowledge and attitudes towards infection prevention measures for protection from respiratory infections. Am J Infect Control. 2021;49(11):1369-1375. doi:10.1016/j.ajic.2021.06.011
Molteni R, Biavasco R, Stefanoni D, et al. Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease. Blood. 2021;138(17):1554-1569. doi:10.1182/blood.2020009594
Erlandson KM, Carter CC, Melbourne K, et al. Weight Change Following Antiretroviral Therapy Switch in People With Viral Suppression: Pooled Data from Randomized Clinical Trials. Clin Infect Dis. 2021;73(8):1440-1451. doi:10.1093/cid/ciab444
Thompson MG, Stenehjem E, Grannis S, et al. Effectiveness of Covid-19 Vaccines in Ambulatory and Inpatient Care Settings. N Engl J Med. 2021;385(15):1355-1371. doi:10.1056/NEJMoa2110362
Pettit AC, Stout JE, Belknap R, et al. Optimal Testing Choice and Diagnostic Strategies for Latent Tuberculosis Infection Among US-Born People Living with Human Immunodeficiency Virus (HIV). Clin Infect Dis. 2021;73(7):e2278-e2284. doi:10.1093/cid/ciaa1135
Firnhaber C, Swarts A, Jezile V, et al. Human Papillomavirus Vaccination Prior to Loop Electroexcision Procedure Does Not Prevent Recurrent Cervical High-grade Squamous Intraepithelial Lesions in Women Living With Human Immunodeficiency Virus: A Randomized, Double-blind, Placebo-controlled Trial. Clin Infect Dis. 2021;73(7):e2211-e2216. doi:10.1093/cid/ciaa1456
Morrow M, MaWhinney S, Coyle RP, et al. Emtricitabine triphosphate in dried blood spots predicts future viremia in persons with HIV and identifies mismatch with self-reported adherence. AIDS. 2021;35(12):1949-1956. doi:10.1097/QAD.0000000000002981
Rumbaut Castillo R, Hurtado Gascón LC, Ruiz-Fuentes JL, et al. Leprosy in children in Cuba: Epidemiological and clinical description of 50 cases from 2012-2019. PLoS Negl Trop Dis. 2021;15(10):e0009910. doi:10.1371/journal.pntd.0009910
Krsak M, Harry BL, Palmer BE, Franco-Paredes C. Postinfectious Immunity After COVID-19 and Vaccination Against SARS-CoV-2. Viral Immunol. 2021;34(8):504-509. doi:10.1089/vim.2021.0054
Heil EL, Bork JT, Abbo LM, et al. Optimizing the Management of Uncomplicated Gram-Negative Bloodstream Infections: Consensus Guidance Using a Modified Delphi Process. Open Forum Infect Dis. 2021;8(10):ofab434. doi:10.1093/ofid/ofab434
Francis J, Mngqibisa R, McIlleron H, et al. A Semimechanistic Pharmacokinetic Model for Depot Medroxyprogesterone Acetate and Drug-Drug Interactions With Antiretroviral and Antituberculosis Treatment. Clin Pharmacol Ther. 2021;110(4):1057-1065. doi:10.1002/cpt.2324
Chu NM, Chen X, Gross AL, et al. Cognitive impairment burden in older and younger adults across the kidney transplant care continuum. Clin Transplant. 2021;35(10):e14425. doi:10.1111/ctr.14425
Chauhan L, Pattee J, Ford J, et al. A Multi-center, Prospective, Observational-cohort controlled study of Clinical Outcomes following COVID-19 Convalescent plasma therapy in hospitalized COVID-19 patients. Clin Infect Dis. Published online September 21, 2021:ciab834. doi:10.1093/cid/ciab834
Stanislawski MA, Frank DN, Borengasser SJ, et al. The Gut Microbiota during a Behavioral Weight Loss Intervention. Nutrients. 2021;13(9). doi:10.3390/nu13093248
Valença-Pereira F, Fang Q, Marié IJ, et al. IL-6 enhances CD4 cell motility by sustaining mitochondrial Ca(2+) through the noncanonical STAT3 pathway. Proc Natl Acad Sci U S A. 2021;118(37). doi:10.1073/pnas.2103444118
Karoor V, Strassheim D, Sullivan T, et al. The Short-Chain Fatty Acid Butyrate Attenuates Pulmonary Vascular Remodeling and Inflammation in Hypoxia-Induced Pulmonary Hypertension. Int J Mol Sci. 2021;22(18). doi:10.3390/ijms22189916
Sungar WG, Angerhofer C, McCormick T, et al. Implementation of holistic review into emergency medicine residency application screening to improve recruitment of underrepresented in medicine applicants. AEM Educ Train. 2021;5(Suppl 1):S10-S18. doi:10.1002/aet2.10662
149.
Ryan PP, Hawkins KL, Altman S, et al. A novel virtual hospital at home model during the coronavirus disease 2019 (COVID-19) pandemic. Infect Control Hosp Epidemiol. 2021;42(9):1140-1142. doi:10.1017/ice.2020.435
Kibbie JJ, Dillon SM, Thompson TA, Purba CM, McCarter MD, Wilson CC. Butyrate directly decreases human gut lamina propria CD4 T cell function through histone deacetylase (HDAC) inhibition and GPR43 signaling. Immunobiology. 2021;226(5):152126. doi:10.1016/j.imbio.2021.152126
Castillo-Mancilla JR, Morrow M, Coyle RP, et al. Low-Level Viremia Is Associated With Cumulative Adherence to Antiretroviral Therapy in Persons With HIV. Open Forum Infect Dis. 2021;8(9):ofab463. doi:10.1093/ofid/ofab463
Hasenkrug KJ, Feldmann F, Myers L, et al. Recovery from Acute SARS-CoV-2 Infection and Development of Anamnestic Immune Responses in T Cell-Depleted Rhesus Macaques. mBio. 2021;12(4):e0150321. doi:10.1128/mBio.01503-21
Javan H, Li L, Schaaf CL, et al. Interleukin-1 Receptor Antagonism Abrogates Acute Pressure Overload-Induced Murine Heart Failure. Ann Thorac Surg. Published online August 19, 2021:S0003-4975(21)01434-X. doi:10.1016/j.athoracsur.2021.07.044
Lange-Maia BS, Buchman AS, Leurgans SE, et al. Racial Differences in the Effect of HIV Status on Motor and Pulmonary Function and Mobility Disability in Older Adults. J Racial Ethn Health Disparities. Published online August 17, 2021. doi:10.1007/s40615-021-01126-0
Masters MC, Perez J, Wu K, et al. Baseline Neurocognitive Impairment (NCI) Is Associated With Incident Frailty but Baseline Frailty Does Not Predict Incident NCI in Older Persons With Human Immunodeficiency Virus (HIV). Clin Infect Dis. 2021;73(4):680-688. doi:10.1093/cid/ciab122
Jankowski CM, Wilson MP, MaWhinney S, et al. Blunted Muscle Mitochondrial Responses to Exercise Training in Older Adults With HIV. J Infect Dis. 2021;224(4):679-683. doi:10.1093/infdis/jiaa799
Shah AS, Helmrath MA, Inge TH, et al. Study protocol: a prospective controlled clinical trial to assess surgical or medical treatment for paediatric type 2 diabetes (ST(2)OMP). BMJ Open. 2021;11(8):e047766. doi:10.1136/bmjopen-2020-047766
Gharamti A, Samara O, Monzon A, et al. Association between cytokine levels, sepsis severity and clinical outcomes in sepsis: a quantitative systematic review protocol. BMJ Open. 2021;11(8):e048476. doi:10.1136/bmjopen-2020-048476
Simberkoff MS, Rattigan SM, Gaydos CA, et al. Impact of mandatory vaccination of healthcare personnel on rates of influenza and other viral respiratory pathogens. Infect Control Hosp Epidemiol. Published online August 5, 2021:1-5. doi:10.1017/ice.2021.324
Johnson TM, Molina KC, Howard AH, et al. Real-World Comparison of Bezlotoxumab to Standard of Care Therapy for Prevention of Recurrent Clostridioides difficile Infection in Patients at High Risk for Recurrence. Clin Infect Dis. Published online August 4, 2021:ciab674. doi:10.1093/cid/ciab674
Hileman CO, Kalayjian RC, Azzam S, et al. Plasma Citrate and Succinate Are Associated With Neurocognitive Impairment in Older People With HIV. Clin Infect Dis. 2021;73(3):e765-e772. doi:10.1093/cid/ciab107
Scarpato S, Pell J, Baduashvili A, et al. Controlling Chaos: How to Construct Electronically Integrated Inpatient Clinical Pathways That Can Disseminate Best Practice Rapidly in Times of Crisis. Am J Med Qual. 2021;36(4):287-289. doi:10.1097/01.JMQ.0000741988.67405.df
Zimmer AJ, Heitkamp P, Malar J, et al. Facility-based directly observed therapy (DOT) for tuberculosis during COVID-19: A community perspective. J Clin Tuberc Other Mycobact Dis. 2021;24:100248. doi:10.1016/j.jctube.2021.100248
Zhao P, Yao Q, Zhang PJ, et al. Single-cell RNA-seq reveals a critical role of novel pro-inflammatory EndMT in mediating adverse remodeling in coronary artery-on-a-chip. Sci Adv. 2021;7(34). doi:10.1126/sciadv.abg1694
Tan S, Kasperbauer S. Nontuberculous Mycobacteria. Semin Respir Crit Care Med. 2021;42(4):567-586. doi:10.1055/s-0041-1730997
Sartain E, Schoeppler K, Crowther B, et al. Perioperative anidulafungin combined with triazole prophylaxis for the prevention of early invasive candidiasis in lung transplant recipients. Transpl Infect Dis. 2021;23(4):e13692. doi:10.1111/tid.13692
Koo S, Bold TD, Cheng MP, et al. A eulogy for Dr Francisco Miguel Marty Forero. Transpl Infect Dis. 2021;23(4):e13645. doi:10.1111/tid.13645
Briukhovetska D, Dörr J, Endres S, Libby P, Dinarello CA, Kobold S. Interleukins in cancer: from biology to therapy. Nat Rev Cancer. 2021;21(8):481-499. doi:10.1038/s41568-021-00363-z
Barbera LK, Kamis KF, Rowan SE, et al. HIV and COVID-19: review of clinical course and outcomes. HIV Res Clin Pract. 2021;22(4):102-118. doi:10.1080/25787489.2021.1975608
Badii M, Gaal OI, Cleophas MC, et al. Urate-induced epigenetic modifications in myeloid cells. Arthritis Res Ther. 2021;23(1):202. doi:10.1186/s13075-021-02580-1
Pandita A, Gil RM, Farmakiotis D. Call for Action: Racial Disparities in Clinical Research. Clin Infect Dis. 2021;73(2):356-357. doi:10.1093/cid/ciaa1349
Marx GE, Biggerstaff BJ, Nawrocki CC, et al. Detection of Severe Acute Respiratory Syndrome Coronavirus 2 on Self-Collected Saliva or Anterior Nasal Specimens Compared With Healthcare Personnel-Collected Nasopharyngeal Specimens. Clin Infect Dis. 2021;73(Suppl 1):S65-S73. doi:10.1093/cid/ciab330
Lake JE, La K, Erlandson KM, et al. Tesamorelin improves fat quality independent of changes in fat quantity. AIDS. 2021;35(9):1395-1402. doi:10.1097/QAD.0000000000002897
Akiyama BM, Graham ME, O Donoghue Z, Beckham JD, Kieft JS. Three-dimensional structure of a flavivirus dumbbell RNA reveals molecular details of an RNA regulator of replication. Nucleic Acids Res. 2021;49(12):7122-7138. doi:10.1093/nar/gkab462
Cohen MS, Nirula A, Mulligan MJ, et al. Effect of Bamlanivimab vs Placebo on Incidence of COVID-19 Among Residents and Staff of Skilled Nursing and Assisted Living Facilities: A Randomized Clinical Trial. JAMA. 2021;326(1):46-55. doi:10.1001/jama.2021.8828
van Ingen J, Aliberti S, Andrejak C, et al. Management of Drug Toxicity in Mycobacterium avium Complex Pulmonary Disease: An Expert Panel Survey. Clin Infect Dis. 2021;73(1):e256-e259. doi:10.1093/cid/ciaa1361
Kelly SG, Wu K, Tassiopoulos K, Erlandson KM, Koletar SL, Palella FJJ. Incorporating Frailty Into the Pooled Cohort Equations to Predict Cardiovascular Disease Among Persons With HIV. J Acquir Immune Defic Syndr. 2021;87(3):971-977. doi:10.1097/QAI.0000000000002662
Haukoos JS, Lyons MS, Rothman RE, et al. Comparison of HIV Screening Strategies in the Emergency Department: A Randomized Clinical Trial. JAMA Netw Open. 2021;4(7):e2117763. doi:10.1001/jamanetworkopen.2021.17763
Gardner EM, Hawkins KL. Same-day Start of Antiretroviral Therapy Demonstrates the Potential To Lessen Disparities in Human Immunodeficiency Virus Treatment Outcomes. Clin Infect Dis. 2021;73(1):e129-e131. doi:10.1093/cid/ciaa618
Vazquez Deida AA, Shihadeh KC, Aragon D, Knepper BC, Jenkins TC. Factors Associated With Longer Than Recommended Durations of Antibiotic Therapy for Uncomplicated Ambulatory Infections in an Integrated Healthcare System. Open Forum Infect Dis. 2021;8(7):ofab324. doi:10.1093/ofid/ofab324
Mueller SW, Kedzior SK, Miller MA, et al. An overview of current and emerging antifungal pharmacotherapy for invasive fungal infections. Expert Opin Pharmacother. 2021;22(10):1355-1371. doi:10.1080/14656566.2021.1892075
Maehigashi T, Ahn S, Kim UI, et al. A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site. PLoS Pathog. 2021;17(7):e1009671. doi:10.1371/journal.ppat.1009671
Luetkemeyer AF, Wyles DL. CROI 2021: Viral Hepatitis and Other Forms of Liver Injury Impacting People with HIV. Top Antivir Med. 2021;29(3):379-385.
Los J, Gaydos CA, Gibert CL, et al. Take-home kits to detect respiratory viruses among healthcare personnel: Lessons learned from a cluster randomized clinical trial. Am J Infect Control. 2021;49(7):893-899. doi:10.1016/j.ajic.2021.02.001
Lofgren SM, Nicol MR, Kandole TK, et al. Short Communication: A Descriptive Analysis of Dried Blood Spot Adherence Testing Among Ugandans with HIV Presenting with Cryptococcal Meningitis. AIDS Res Hum Retroviruses. 2021;37(7):529-533. doi:10.1089/AID.2020.0202
Johnson TM, Howard AH, Miller MA, et al. Effectiveness of Bezlotoxumab for Prevention of Recurrent Clostridioides difficile Infection Among Transplant Recipients. Open Forum Infect Dis. 2021;8(7):ofab294. doi:10.1093/ofid/ofab294
Johnson KA, Niu X, Glidden DV, et al. Lower Urine Tenofovir Concentrations Among Individuals Taking Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate: Implications for Point-of-Care Testing. Open Forum Infect Dis. 2021;8(7):ofab200. doi:10.1093/ofid/ofab200
Frank DN, Giese APJ, Hafren L, et al. Otitis media susceptibility and shifts in the head and neck microbiome due to SPINK5 variants. J Med Genet. 2021;58(7):442-452. doi:10.1136/jmedgenet-2020-106844
Dillon SM, Abdo MH, Wilson MP, et al. A Unique Gut Microbiome-Physical Function Axis Exists in Older People with HIV: An Exploratory Study. AIDS Res Hum Retroviruses. 2021;37(7):542-550. doi:10.1089/AID.2020.0283
Coleman KJ, Chauhan L, Piquet AL, Tyler KL, Pastula DM. An Overview of Jamestown Canyon Virus Disease. Neurohospitalist. 2021;11(3):277-278. doi:10.1177/19418744211005948
Niemeyer BF, Miller CM, Ledesma-Feliciano C, et al. Broad antiviral and anti-inflammatory efficacy of nafamostat against SARS-CoV-2 and seasonal coronaviruses in primary human bronchiolar epithelia. Nano Sel. Published online June 30, 2021. doi:10.1002/nano.202100123
Abbott R, Abbott TD, Abraham S, et al. Constraints on Cosmic Strings Using Data from the Third Advanced LIGO-Virgo Observing Run. Phys Rev Lett. 2021;126(24):241102. doi:10.1103/PhysRevLett.126.241102
Castleman MJ, Dillon SM, Thompson TA, et al. Gut Bacteria Induce Granzyme B Expression in Human Colonic ILC3s In Vitro in an IL-15-Dependent Manner. J Immunol. 2021;206(12):3043-3052. doi:10.4049/jimmunol.2000239
Schultz JS, Sparks H, Beckham JD. Arboviral central nervous system infections. Curr Opin Infect Dis. 2021;34(3):264-271. doi:10.1097/QCO.0000000000000729
Costello A, Pandita A, Devitt J. Case Report: Thrombotic Thrombocytopenia after COVID-19 Janssen Vaccination. Am Fam Physician. 2021;103(11):646-647.
Vickery TW, Armstrong M, Kofonow JM, et al. Specialized pro-resolving mediator lipidome and 16S rRNA bacterial microbiome data associated with human chronic rhinosinusitis. Data Brief. 2021;36:107023. doi:10.1016/j.dib.2021.107023
Shepard Z, Rios M, Solis J, et al. Common Dermatologic Conditions in Returning Travelers. Curr Trop Med Rep. 2021;8(2):104-111. doi:10.1007/s40475-021-00231-8
Mundo W, Berning A, Koullias Y, et al. Disseminated Cryptococcal Disease in A Patient With Chronic Chylothorax and a Pleurovenous Catheter, a Case Report With Autopsy Findings. Open Forum Infect Dis. 2021;8(6):ofab258. doi:10.1093/ofid/ofab258
Mortaji P, Corbisiero MF, Vrolijk MA, Henao-Martínez AF, Franco-Paredes C. Chronicle of Jails and Prisons COVID-19 Deaths Foretold. Am J Med Sci. 2021;361(6):801-802. doi:10.1016/j.amjms.2021.01.002
McCormick DW, Rowan SE, Pappert R, et al. Bartonella Seroreactivity Among Persons Experiencing Homelessness During an Outbreak of Bartonella quintana in Denver, Colorado, 2020. Open Forum Infect Dis. 2021;8(6):ofab230. doi:10.1093/ofid/ofab230
Macias Gil R, Touzard-Romo F, Sanchez MC, et al. Characteristics and outcomes of Hispanic/Latinx patients with coronavirus disease 19 (COVID-19) requiring hospitalization in Rhode Island: a retrospective cohort study. Ann Epidemiol. 2021;58:64-68. doi:10.1016/j.annepidem.2021.03.003
Li S, Jiang L, Beckmann K, et al. A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signaling. J Biol Chem. 2021;296:100630. doi:10.1016/j.jbc.2021.100630
Ibrahim ME, Castillo-Mancilla JR, Yager J, et al. Individualized Adherence Benchmarks for HIV Pre-Exposure Prophylaxis. AIDS Res Hum Retroviruses. 2021;37(6):421-428. doi:10.1089/AID.2020.0108
Haukoos JS, White DAE, Rowan SE, et al. HIV Risk and Pre-Exposure Prophylaxis Eligibility Among Emergency Department Patients. AIDS Patient Care STDS. 2021;35(6):211-219. doi:10.1089/apc.2021.0012
Grivas P, Khaki AR, Wise-Draper TM, et al. Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer: a report from the COVID-19 and Cancer Consortium. Ann Oncol. 2021;32(6):787-800. doi:10.1016/j.annonc.2021.02.024
Gharamti AA, Mei F, Jankousky KC, et al. Diagnostic Utility of a Ferritin-to-Procalcitonin Ratio to Differentiate Patients With COVID-19 From Those With Bacterial Pneumonia: A Multicenter Study. Open Forum Infect Dis. 2021;8(6):ofab124. doi:10.1093/ofid/ofab124
Erlandson KM, Piggott DA. Frailty and HIV: Moving from Characterization to Intervention. Curr HIV/AIDS Rep. 2021;18(3):157-175. doi:10.1007/s11904-021-00554-1
Cordero JH, Shepard Z, Schultz J, et al. Dermatologic Manifestations of Tick-borne Diseases in Travelers. Curr Trop Med Rep. 2021;8(2):99-103. doi:10.1007/s40475-021-00230-9
Chai PR, Goodman G, Bustamante MJ, et al. Long-Term Stability of the Electronic Sensor Component of a Digital Pill System in Real-World Storage Settings. J Pharm Technol. 2021;37(3):135-139. doi:10.1177/8755122520985219
Hyson P, Barahona LV, Pedraza-Arévalo LC, et al. Experiences with Diagnosis and Treatment of Chagas Disease at a United States Teaching Hospital-Clinical Features of Patients with Positive Screening Serologic Testing. Trop Med Infect Dis. 2021;6(2). doi:10.3390/tropicalmed6020093
Alvarado-Socarras JL, Vargas-Soler JA, Franco-Paredes C, Villegas-Lamus KC, Rojas-Torres JP, Rodriguez-Morales AJ. A Cluster of Neonatal Infections Caused by Candida auris at a Large Referral Center in Colombia. J Pediatric Infect Dis Soc. 2021;10(5):549-555. doi:10.1093/jpids/piaa152
van Deuren RC, Arts P, Cavalli G, et al. Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses. Genome Med. 2021;13(1):94. doi:10.1186/s13073-021-00907-w
Jha V, Nicholson LK, Gardner EM, et al. Impact of HIV-1 Infection and Antigen Class on T Follicular Helper Cell Responses to Pneumococcal Polysaccharide-Protein Conjugate Vaccine-13. J Immunol. 2021;206(10):2402-2411. doi:10.4049/jimmunol.2001133
Falutz J, Brañas F, Erlandson KM. Frailty: the current challenge for aging people with HIV. Curr Opin HIV AIDS. 2021;16(3):133-140. doi:10.1097/COH.0000000000000677
Siebert JC, Stanislawski MA, Zaman A, et al. Multiomic Predictors of Short-Term Weight Loss and Clinical Outcomes During a Behavioral-Based Weight Loss Intervention. Obesity (Silver Spring). 2021;29(5):859-869. doi:10.1002/oby.23127
Schultz J, Beeson A, Newton T, et al. Impact of An Internal Medicine-Pediatrics Residency Quality Improvement Project to Increase Latent Tuberculosis Screening. Am J Med Sci. 2021;361(5):670-672. doi:10.1016/j.amjms.2020.10.033
Li Z, Wang-Heaton H, Cartwright BM, et al. ATR prevents Ca(2+) overload-induced necrotic cell death through phosphorylation-mediated inactivation of PARP1 without DNA damage signaling. FASEB J. 2021;35(5):e21373. doi:10.1096/fj.202001636RRR
Jenkins TC, Tamma PD. Thinking Beyond the “Core” Antibiotic Stewardship Interventions: Shifting the Onus for Appropriate Antibiotic Use from Stewardship Teams to Prescribing Clinicians. Clin Infect Dis. 2021;72(8):1457-1462. doi:10.1093/cid/ciaa1003
Chai PR, Bustamante MJ, Goodman G, et al. A Brief Training Program to Support the Use of a Digital Pill System for Medication Adherence: Pilot Descriptive Study. JMIR Form Res. 2021;5(4):e26213. doi:10.2196/26213
Feng PJ, Wu Y, Ho CS, et al. Impact of T-Cell Xtend on T-SPOT.TB Assay in High-Risk Individuals after Delayed Blood Sample Processing. J Clin Microbiol. 2021;59(5). doi:10.1128/JCM.00120-21
Benamu E, Gajurel K, Anderson JN, et al. Plasma Microbial Cell-free DNA Next Generation Sequencing in the Diagnosis and Management of Febrile Neutropenia. Clin Infect Dis. Published online April 19, 2021:ciab324. doi:10.1093/cid/ciab324
Nicholson LT, Pidgeon TS, Lauder A, Rellan I, Richard MJ, Ruch DS. Lunate Revascularization With Temporary Internal Radiocarpal Spanning Fixation for Kienböck Disease. Hand (N Y). Published online April 15, 2021:15589447211006858. doi:10.1177/15589447211006858
Malik SA, Zhu C, Li J, et al. Impact of preoperative antibiotics and other variables on integrated microbiome-host transcriptomic data generated from colorectal cancer resections. World J Gastroenterol. 2021;27(14):1465-1482. doi:10.3748/wjg.v27.i14.1465
van der Heijden WA, Van de Wijer L, Keramati F, et al. Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells. JCI Insight. 2021;6(7):145928. doi:10.1172/jci.insight.145928
Erlandson KM, Wilson MP, MaWhinney S, et al. The Impact of Moderate or High-Intensity Combined Exercise on Systemic Inflammation Among Older Persons With and Without HIV. J Infect Dis. 2021;223(7):1161-1170. doi:10.1093/infdis/jiaa494
Cavalli G, Tengesdal IW, Gresnigt M, et al. The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity. Cell Rep. 2021;35(1):108955. doi:10.1016/j.celrep.2021.108955
Hasenkrug KJ, Feldmann F, Myers L, et al. Recovery from acute SARS-CoV-2 infection and development of anamnestic immune responses in T cell-depleted rhesus macaques. bioRxiv. Published online April 4, 2021:2021.04.02.438262. doi:10.1101/2021.04.02.438262
Oliveira VHF, Borsari AL, Cárdenas JDG, et al. Low Agreement Between Initial and Revised European Consensus on Definition and Diagnosis of Sarcopenia Applied to People Living With HIV. J Acquir Immune Defic Syndr. 2021;86(4):e106-e113. doi:10.1097/QAI.0000000000002576
Abdo M, Langan SJ, MaWhinney S, et al. Effect of Statin Therapy on Age-Associated Changes in Physical Function Among Men With and Without HIV in the Multicenter AIDS Cohort Study. J Acquir Immune Defic Syndr. 2021;86(4):455-462. doi:10.1097/QAI.0000000000002579
Taimur S, Pouch SM, Zubizarreta N, et al. Impact of pre-transplant carbapenem-resistant Enterobacterales colonization and/or infection on solid organ transplant outcomes. Clin Transplant. 2021;35(4):e14239. doi:10.1111/ctr.14239
Rebensburg SV, Wei G, Larue RC, et al. Sec24C is an HIV-1 host dependency factor crucial for virus replication. Nat Microbiol. 2021;6(4):435-444. doi:10.1038/s41564-021-00868-1
Krsak M, Wada NI, Plankey MW, et al. Self-Reported Cannabis Use and Markers of Inflammation in Men Who Have Sex With Men With and Without HIV. Cannabis Cannabinoid Res. 2021;6(2):165-173. doi:10.1089/can.2019.0083
Krsak M, Henao-Martínez AF, Franco-Paredes C. COVID-19: Way Forward With Serosurveillance Without Overemphasizing Neutralizing Antibodies. Viral Immunol. 2021;34(3):130-133. doi:10.1089/vim.2020.0246
Goldschmidt AB, Khoury JC, Mitchell JE, et al. Loss of Control Eating and Health Indicators Over 6 Years in Adolescents Undergoing Metabolic and Bariatric Surgery. Obesity (Silver Spring). 2021;29(4):740-747. doi:10.1002/oby.23126
Franco-Paredes C, Suarez JA, Henao-Martínez AF. Global COVID-19 vaccine equity should precede requiring travelers proof of vaccination. Int J Infect Dis. 2021;105:243-244. doi:10.1016/j.ijid.2021.02.061
Dillon SM, Wilson CC. Gut Innate Immunity and HIV Pathogenesis. Curr HIV/AIDS Rep. 2021;18(2):128-138. doi:10.1007/s11904-021-00544-3
Auma AWN, Shive C, Damjanovska S, et al. T-cell Activation Is Correlated With Monocyte Activation in HCV/HIV Coinfection and Declines During HCV Direct-Acting Antiviral Therapy. Open Forum Infect Dis. 2021;8(4):ofab079. doi:10.1093/ofid/ofab079
Allan R, Wiebe SA, Johnson SM, Piaseckyj O, Campbell TL. Practicing Emotionally Focused Therapy online: Calling all relationships. J Marital Fam Ther. 2021;47(2):424-439. doi:10.1111/jmft.12507
Read JM, Zimmer S, Vukotich CJ, et al. Influenza and other respiratory viral infections associated with absence from school among schoolchildren in Pittsburgh, Pennsylvania, USA: a cohort study. BMC Infect Dis. 2021;21(1):291. doi:10.1186/s12879-021-05922-1
Eller KA, Aunins TR, Courtney CM, et al. Facile accelerated specific therapeutic (FAST) platform develops antisense therapies to counter multidrug-resistant bacteria. Commun Biol. 2021;4(1):331. doi:10.1038/s42003-021-01856-1
Lundgren JD, Grund B, Barkauskas CE, et al. A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19. N Engl J Med. 2021;384(10):905-914. doi:10.1056/NEJMoa2033130
Tengesdal IW, Menon DR, Osborne DG, et al. Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion. Proc Natl Acad Sci U S A. 2021;118(10). doi:10.1073/pnas.2000915118
Sabourin KR, Schultz J, Romero J, et al. Risk Factors of SARS-CoV-2 Antibodies in Arapahoe County First Responders-The COVID-19 Arapahoe SErosurveillance Study (CASES) Project. J Occup Environ Med. 2021;63(3):191-198. doi:10.1097/JOM.0000000000002099
Erlandson KM, Wu K, Lake JE, et al. Mitochondrial DNA haplogroups and weight gain following switch to integrase strand transfer inhibitor-based antiretroviral therapy. AIDS. 2021;35(3):439-445. doi:10.1097/QAD.0000000000002771
Canfield GS, Chatterjee A, Espinosa J, et al. Lytic bacteriophages facilitate antibiotic sensitization of Enterococcus faecium. Antimicrob Agents Chemother. 2021;65(5):AAC.00143-21. doi:10.1128/AAC.00143-21
Zeller MH, Kidwell KM, Reiter-Purtill J, et al. Cigarette Use and Adolescent Metabolic and Bariatric Surgery. Obesity (Silver Spring). 2021;29(3):579-586. doi:10.1002/oby.23084