Dr. Katherine Frasca Has Created a COVID-19 TipSheet/Survival Guide Based on Her and Our Other ID Physicians' First-hand Experience

Dr. Frasca recently attended to numerous COVID-19 inpatients and has compiled this very helpful and practical resource which can be found in our COVID-19 document collection on our division's COVID-19 resources page. Stay tuned for expansions and refinements by her and our other physicians of this living document. 

Associate Professor David Beckham, MD Has Been at the Forefront of Efforts to Deploy Convalescent Plasma for COVID-19 Patients in Colorado

Dr. Beckham was featured in a recent news report about how researchers and clinicians are working together on our campus to make a serum test available. The University of Colorado Hospital was the first in the state to treat COVID-19 patients with convalescent serum. This work is supported in part by a CCTSI pilot award.

Division Faculty Advocate for Immigrant and Disadvantaged Populations

Dr. Carlos Franco-Paredes works with a national network of physicians dedicated to provide medical care for immigrants under ICE custody. Dr. Michelle Haas has been volunteering in the Human Rights Clinic (HRC) at Denver Health. Janine Young and Jaime Moo-Young lead the HRC.  In response to COVID-19, Carlos has actively collaborated with RMAIN, ACLU, Southern Poverty Law Center, and numerous immigration attorneys to promote the release of detained immigrants on humanitarian parole. Implementing interventions such as social distancing and infection prevention is a major challenge in for-profit overcrowded detention centers.

ID Faculty Photo Panel Now Available on ID Division Website

The "Faces of the ID Division" card below provides a photo panel showing our faculty arranged in order of year of appointment to the CU SOM faculty. The 72 faculty distribute as follows: AMC-51, Denver Health-15, Veterans' Affairs-4 (7 counting joint roles), NJH-2. On the AMC (UCH), there are 40 ID clinicians who staff our inpatient and outpatient ID services (32 physicians, 8 APPs). Fourteen of our faculty have laboratory-based programs in Research Complex 2 (RC2).

Weekly Division Case Conferences Have Moved to a Virtual Format

In response to COVID-19, the Division’s weekly Case Conference is now a virtual series that will focus on this new infectious disease and engage the campus and the broader Colorado medical community. Fellows and faculty present and discuss COVID-19 cases and medical students provide a literature review. This is a joint collaboration between CU Anschutz, Denver Health, Colorado IDSA, and ECHO Colorado.

Professor Shanta Zimmer Rolls Out New COVID-19 Course at the CU School of Medicine

Professor Zimmer, Senior Associate Dean for Education, has led a team of educators and students in setting up the COVID-19 Pandemic Response Elective Course in record time. It is also posted at the iCollaborative website of the AAMC.

Professors Eric Poeschla, Steven Johnson, and Thomas Campbell Present COVID-19 Grand Rounds

Their grand rounds [video link]  presentation on April 1 gave an overview of epidemiological modeling, origins and properties of SARS-CoV-2, clinical features, and treatment. They were joined by Professor Jonathan Samet from the CU School of Public Health.

Division Activates Additional Inpatient ID Service in Response to COVID-19

On 24 March, the Division activated a 5th inpatient ID service (Green) to meet the needs of COVID-19 patients. The pre-existing services are Gold ID, Blue ID, Ortho-ID and Transplant ID. In addition, faculty are participating in several COVID-19 clinical trials, organizing outpatient follow-up visits, providing updated treatment and monitoring guidelines, and supervising hospital infection control.

We Welcome Five Incoming Faculty Members

The Division is Growing. In July we will be 72 faculty members strong. A fifth inpatient service will soon start at University of Colorado Hospital. We are delighted to officially announce five new ID Division faculty members who will join us in mid-2020. They collectively bring a wealth of talent, training and diverse experiences to our three-shield missions:

Yiannis Koullias, MD comes to us from the Partners ID fellowship at Harvard Medical School/Brigham & Women’s Hospital/MGH, with subspecialty training in Transplant ID at Dana-Farber/Brigham and Women’s Cancer Center. He is a graduate of Harvard College, Duke Medical School, and the Brigham’s Internal Medicine Residency Program. His has broad interests in Transplant ID, including viral and fungal infections in heme-onc/BMT populations.

Sarah Mann, MD joins us from our ID fellowship here at the University of Colorado School of Medicine. She is a graduate of Cornell University, George Washington University Medical School and the Harbor UCLA internal medicine residency. She has interests in HIV Medicine and works on stewardship of anti-retroviral agents.

Aakriti Pandita, MD joins us from the Infectious Disease Fellowship at Warren Alpert Medical School of Brown University. She is a graduate of the Sher-i-Kashmir Institute of Medical Sciences in Srinagar, India, and the SUNY Upstate Medical University internal medicine residency. She is jointly appointed with the Division of Hospital Medicine. She is currently working on a meta-analysis of decades-long time trends in Staphylococcus aureus bacteremia. She also has a strong interest in tuberculosis and advocacy.

Rebecca Rwubusisi MSN, BSN, is our new APP for the Transplant ID (TID) service on the AMC. She is an Acute Care Nurse Practitioner whose valuable experience includes 15 years of bedside experience as an RN in the Department of Surgery, on the UC Health Inpatient Transplant Unit. She also has medical experience in East Africa and is fluent in Spanish.

Sias Scherger, MD also joins the division from our ID fellowship. He is a graduate of the University of Nebraska, the University of Nebraska College of Medicine and the Wake Forest internal medicine residency. He has interests in transplant ID and is working on understanding associations between anti-cytokine antibodies and endemic fungal infections.

Responding to COVID-19. The CU Infectious Diseases Division Continues to be Deeply Involved in Institutional Preparations for the Coronavirus Pandemic

Drs. Michelle Barron and Larissa Pisney (University of Colorado Hospital Infection Control and Prevention) are at the head of a multi-faceted campaign to ready our UCH providers and trainees and have been coordinating with state and national authorities. Drs. Mary Bessesen and Heather Young have been performing similar roles at the VA Medical Center and Denver Health. Dr. Brian Montague is involved in managing employee health for both the School of Medicine and UCH. Numerous other ID faculty members have participated in patient care, screening and testing, contingency planning, guidelines preparation, communications and community outreach, scientific discussions, idea generation, and teaching.  Division scientists are working on various research aspects of understanding, preventing and treating viral infections. The Infectious Disease Fellows are involved in consulting on COVID-19 issues and they will also be working with the Colorado Dept. of Public Health in the coming month to learn about the role of epidemiologists and about public health policy.  The Division website aggregator contains much practical information, both local and international.

Dr. Michelle Barron Speaks at UCHealth Town Hall on COVID-19 Response

Dr. Barron, Medical Director of Infection Control and Prevention, discussed COVID-19 basics, screening and treatment guidelines, and infection control measures. The entire town hall can be watched here.

Drs. Robert Belknap, David Cohn and Randall Reves Participate in Multi-institutional Team to Update Guidelines for Treatment of Latent Tuberculosis.

Their participation is part of the important role that Denver Health ID faculty continue to play in M. tuberculosis treatment and control, in Colorado and internationally. See Sterling et al. in MMWR in "Recent Publications" below for full details of the team's report.

Dr. Lakshmi Chauhan Receives the Outstanding Quality Award at 2nd Annual UCH Quality & Safety Symposium

Dr. Chauhan was awarded for her outpatient stewardship project “Approaches to Decrease Inappropriate Antibiotic use in Acute Respiratory Conditions in a Geriatric Clinic.” She will present her project on March 11, 2020. Her goals are to work with the antimicrobial stewardship team to help expand outpatient stewardship programs to other UCH clinics. Quality improvement projects such as this are important areas for academic contribution and grant funding opportunities in the division.

Dr. Sarah Rowan Discusses Colorado's Ongoing Fight to End HIV with 5280 Magazine.

Dr. Rowan spoke about her work on a local HIV task force to expand testing and treatment of the virus and about other efforts by the Colorado medical community to combat HIV.

Congratulations to Fellowship Program Director Dr. Carlos Franco-Paredes and Education Coordinator Kelly Rico for Highly Positive ACGME Annual Program Review.  

The Review Committee found no concerns and commended the program for its demonstrated excellent compliance with the ACGME's Program Requirements.

ID Fellows Greg Canfield and Sarah Mann Publish a Striking Example of Cutaneous Blastomycosis.

Drs. Canfield and Mann published their results in Clinical Infectious Diseases.  The case exhibited numerous interesting features including the classic - and in this case, quite developed - verrucous lesion with raised, sharply demarcated borders. 

 

Dr. Hillary Dunlevy Awarded Annual CU Hospital Physician Medical Staff Award

Dr. Hillary Dunlevy, Assistant Professor of Medicine, was awarded the Annual University of Colorado Hospital Full-time Physician Medical Staff Award on January 30, 2020. Recipients of this award exemplify the mission and vision of UCH and are recognized for achievement in one or more of the following areas:  Amazing patient care; Outstanding teaching of student physicians; Improvements in services offered/collaboration with other specialties; Community service.

Rebecca Rwubusisi MSN, BSN, RN, CCTN Joins Our Team as the New APP for Transplant ID Service

Her appointment will provide significant assistance to our physician providers and facilitate the patient care, education and research missions of the TID focus group. Rebecca received her BSN Magna Cum Laude from the University of Colorado Denver in 2005. She is an Acute Care Nurse Practitioner whose extensive experience includes 15 years of bedside experience as an RN in the Department of Surgery, on the UC Health Inpatient Transplant Unit. There she gained an in-depth understanding of the multi-faceted transplantation process and close working relationships with transplant providers. She developed a passion for Infectious Diseases as well, prompting her to transition to our Division. During three months in Rwanda, Rebecca also saw and treated patients with multiple infectious problems, including HIV/AIDS. Moreover, she is fluent in Spanish.

 

Debra Best Joins Our Division as Our New Post-Award Administrator

She will begin her role on Monday, February 3rd, 2020.

Dr. Cara Wilson has been appointed Associate Director of the Medical Scientist Training Program

Dr. Wilson will transition into the director role on July 1, 2020. Our MD-PhD program is a critical linchpin in the education of physician-scientists, allowing top-notch students to obtain their PhD alongside their MD. The program provides tuition as well as an annual stipend.

Dr. Michelle Barron Discusses Infection Prevention with Boulder Daily Camera

Michelle Barron, UCHealth University of Colorado Hospital’s medical director of infection prevention and professor of medicine at CU School of Medicine was recently interviewed by  the Daily Camera. She discussed how Boulder County has managed to avoid the worst of a state and nationwide Hepatitis A outbreak.

Dr. Tom Campbell to lead scientific review group on HIV

Dr. Tom Campbell has been nominated to lead the new Section Review Group of the NIH-CDC-HIVMA-/IDSA Guidelines for Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV.

Dr. Kristine Erlandson Announced as Outstanding Early Career Scholar

The University of Colorado Department of Medicine has selected the 2017 recipients for its Outstanding Early Career Scholar Program, HIV/AIDS researcher Kristine Erlandson, MD, and cardiology researcher Kunhua Song, PhD. The program aims to accelerate the careers of promising researchers in the Department of Medicine.

Santiago and Wilson labs frame the gene expression landscape of HIV-1 infected gut T cells exposed to enteric bacteria February 2017

Broncos fever is spreading through Denver and beyond! Have you been exposed? Dr. Michelle Barron talks about the fandemic

Dr. David Beckham discusses his role in the fight against the Zika Virus with the Aurora Sentinel

Dr. Kejun Guo highlighted as being a successful international scholar

Dr. David Wyles, New ID Division Chief at Denver Health

Professor Dinarello publishes review on inflammation and arthritis in Nature Reviews Rheumatology.
Dr. Kristine Erlandson received 2016 ACTG John Carey Young Investigator Award

Dr. David Beckham discusses details surrounding the Zika virus

Arjun Srinivasan, MD, of the CDC, presented a national update on antibiotic stewardship. Dr. Norihiro Yogo, diretor of antimicrobial stewardship at UCH, and Matt Miller, PharmD, were mentioned due to their involvement in developing guidelines for treating common infections

Dr. Michelle Barron discusses mosquito prevention in an article featured in the Denver Post

Q & A with Dr. Michelle Barron- featured on CU Medicine Today through the School of Medicine

Dr. Jose Castillo-Mancilla selected as a Department of Medicine 2016 Rising Star

Dr. Bill Burman, Director of Denver Public Health, named interim CEO of Denver Health

Poeschla laboratory reports newtransgenic model of stably augmented innate immunity in PLoS Pathogens

Dr. Connnie Price named CMO at Denver Health

DOM’s Richard Johnson and Dr.Eric Poeschla Elected to the Association of American Physicians

Beckham Lab discovers that alpha-synuclein, the protein that causes Parkinson’s disease, functions as a neuron-specific restriction factor to inhibit viral infections in the brain

Connick Lab reports novel findings on the roles of follicular regulatory T cells in HIV and SIV disease in Nature Communications

Dr. Elizabeth Connick invited to serve on the Office of AIDS Research Advisory Council

Wilson lab reports in Mucosal Immunology that gut dendritic cell activation links an altered colonic microbiome to mucosal and systemic T-cell activation in untreated HIV-1 infection

Santiago and Wilson Labs report on the role of Interferon-α Subtypes in mucosal HIV-1 Infection

Dr. Cara Wilson appointed DOM Vice Chair for Faculty Development

Dr. Charles Dinarello Named University Distinguished Professor

Dr. Thomas Campbell Awarded Excellence in Global Health

Dr. Charles Dinarello Receives Lifetime Achievement Award

Charles Dinarello Receives Honorary Doctorate

Welcome to the Division of Infectious Diseases at the University of Colorado School of Medicine. This message is addressed to our colleagues, patients and members of the public with an interest in the problems and challenges of infectious diseases.

Our faculty, more than 70 and growing, take care of patients with infectious diseases in the mountain west and across the world, do scientific research on major infectious disease (ID) health problems, and educate the next generation of physicians and scientists in our field.

We work mainly at three sites located across the Denver metropolitan area:

1. The Anschutz Medical Campus (AMC). The AMC, which contains the School of Medicine (SOM) and is located in Aurora, just east of the Denver city line, was built to accommodate the growth of the SOM and fulfill its need for cutting edge facilities for research, education, and clinical missions. Many of the Infectious Diseases Division faculty are located physically in Research Complex 2 in the research quadrangle, where we have state of the art laboratories and bio-containment facilities for work with infectious agents. AMC ID physicians, physician assistants and nurse... practitioners take care of hospitalized patients in the University of Colorado Hospital (UCH). We take care of outpatients in our Infectious Disease Group Practice (IDGP) in the UCH outpatient pavilion.

2. Denver Health (DH). This municipal, integrated model public health care system serves a broad range of patients in Colorado, with education and research as two of its strategic pillars. DH is comprised of the Denver Health Medical Center (DHMC), a community health program with 8 centers and 16 school-based clinics in Denver, and the City and County health department (Denver Public Health, DPH). Infectious Diseases faculty are located in both DPH and the Department of Medicine of DHMC. Denver Public Health clinics include the ID Clinic and Center for Positive Health (HIV), the Denver Metro Tuberculosis (TB) Clinic serving the 7-county Metro area for diagnosis and treatment of TB and latent TB infection, and the Immunization and Travel Clinic (over 21,000 vaccinations to 10,000 patients per year). DHMC, in partnership with the Colorado Department of Health and Environment, is one of nine designated regional Ebola and other special pathogen treatment centers in the U.S.

Recent Publications

 

Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease.

Abbate A, Toldo S, Marchetti C, Kron J, Van Tassell BW, Dinarello CA.

Circ Res. 2020 Apr 24;126(9):1260-1280. doi: 10.1161/CIRCRESAHA.120.315937. Epub 2020 Apr 23.

PMID: 32324502

 

Novel Coronavirus Disease (COVID-19) Serosurveillance May Facilitate Return-to-Work Decisions.

Krsak M, Johnson SC, Poeschla EM.

Am J Trop Med Hyg. 2020 Apr 23. doi: 10.4269/ajtmh.20-0302. [Epub ahead of print]

PMID: 32329432

 

Development of IFN-Stimulated Gene Expression from Embryogenesis through Adulthood, with and without Constitutive MDA5 Pathway Activation.

Bankers L, Miller C, Liu G, Thongkittidilok C, Morrison J, Poeschla EM.

J Immunol. 2020 Apr 10. pii: ji1901421. doi: 10.4049/jimmunol.1901421. [Epub ahead of print]

PMID: 32277054

 

Partial Normalization of Biomarkers of Inflammation and Immune Activation Among Virally Suppressed Men With HIV Infection and High ART Adherence.

Castillo-Mancilla JR, Brown TT, Palella FJ Jr, Macatangay BJC, Breen EC, Jacobson LP, Wada NI.

Open Forum Infect Dis. 2020 Mar 23;7(4):ofaa099. doi: 10.1093/ofid/ofaa099. eCollection 2020 Apr.

PMID: 32322603

 

Cutaneous Leishmaniasis due to Leishmania (Viannia) panamensis in Two Travelers Successfully Treated with Miltefosine.

Mann S, Phupitakphol T, Davis B, Newman S, Suarez JA, Henao-Martínez A, Franco-Paredes C.

Am J Trop Med Hyg. 2020 Apr 20. doi: 10.4269/ajtmh.20-0086. [Epub ahead of print]

PMID: 32314693

 

Application of Selected Muscle Strength and Body Mass Cut-Points for the Diagnosis of Sarcopenia in Men and Women with or at risk for HIV Infection.

Erlandson KM, Travison TG, Zhu H, Magaziner J, Correa-de-Araujo R, Cawthon PM, Bhasin S, Manini T, Fielding RA, Palella FJ, Kingsley L, Lake JE, Sharma A, Tien PC, Weber KM, Yin MT, Brown TT.

J Gerontol A Biol Sci Med Sci. 2020 Apr 7. pii: glaa083. doi: 10.1093/gerona/glaa083. [Epub ahead of print]

PMID: 32301484

 

Re-treatment of Hepatitis C Infection After Multiple Failures of Direct-Acting Antiviral Therapy.

Fierer DS, Wyles DL.

Open Forum Infect Dis. 2020 Mar 16;7(4):ofaa095. doi: 10.1093/ofid/ofaa095. eCollection 2020 Apr.

PMID: 32296728

Reply to: Trials of Tuberculosis Preventive Therapy in People with HIV Infection.

Stout JE, Turner NA, Belknap RW, Horsburgh CR, Sterling TR, Phillips PPJ.

Am J Respir Crit Care Med. 2020 Apr 13. doi: 10.1164/rccm.202003-0855LE. [Epub ahead of print] No abstract available.

PMID: 32282235

 

Early progression and immune reconstitution inflammatory syndrome during treatment of mild-to-moderate Kaposi sarcoma in sub-Saharan Africa and South America: Incidence, long-term outcomes and effects of early chemotherapy.

Nyirenda M, Ngongondo M, Kang M, Umbleja T, Krown SE, Godfrey C, Samaneka W, Mngqibisa R, Hoagland B, Mwelase N, Caruso S, Martinez-Maza O, Dittmer DP, Borok M, Hosseinipour MC, Campbell TB; A5264/AMC-067 team.

J Acquir Immune Defic Syndr. 2020 Apr 4. doi: 10.1097/QAI.0000000000002361. [Epub ahead of print]

PMID: 32265361

 

Albert Camus' 'The COVID-19 Plague' Revisited.
Franco-Paredes C.Clin Infect Dis. 2020 Apr 17:ciaa454. doi: 10.1093/cid/ciaa454. Online ahead of print.PMID: 32301966 No abstract available

COVID-19 and the coming epidemic in US immigration detention centres.
Meyer JP, Franco-Paredes C, Parmar P, Yasin F, Gartland M.Lancet Infect Dis. 2020 Apr 15:S1473-3099(20)30295-4. doi: 10.1016/S1473-3099(20)30295-4. Online ahead of print.PMID: 32304631 No abstract available.

Unexpected etiology of a pleural empyema in a patient with chronic lymphocytic leukemia (CLL): Capnocytophaga ochracea.
Basco SA, Steele GM, Henao-Martínez AF, Franco-Paredes C, Chastain DB.IDCases. 2020 Mar 20;20:e00747. doi: 10.1016/j.idcr.2020.e00747. eCollection 2020.PMID: 32300526 Free PMC article.

 

CMV myocarditis in solid organ transplant recipients: A case series and review of literature.

Scherger S, Mathur S, Bajrovic V, Johnson SC, Benamu E, Ramanan P, Wolfel E, Levi ME, Abidi MZ.

Transpl Infect Dis. 2020 Mar 30:e13282. doi: 10.1111/tid.13282.  Review. PMID: 32232951

 

Five-year kidney outcomes of bariatric surgery differ in severely obese adolescents and adults with and without type 2 diabetes.

 

Bjornstad P, Nehus E, Jenkins T, Mitsnefes M, Moxey-Mims M, Dixon JB, Inge TH.

Kidney Int. 2020 Feb 3. pii: S0085-2538(20)30114-9. doi: 10.1016/j.kint.2020.01.016. PMID: 32229096

 

Advantages of Outpatient Treatment with Long-Acting Lipoglycopeptides for Serious Gram-Positive Infections: A Review.

Krsak M, Morrisette T, Miller M, Molina K, Huang M, Damioli L, Pisney L, Wong M, Poeschla E.

Pharmacotherapy. 2020 Apr 2. doi: 10.1002/phar.2389. Epub ahead PMID: 32239771

 

Intramedullary spinal cord lesions in an immunocompromised host due to Mycobacterium haemophilum.

Kon S, Franco-Paredes C, Hawkins KL.

IDCases. 2019 Nov 22;19:e00674. doi: 10.1016/j.idcr.2019.e00674. eCollection 2020. PMID: 32226763

 

Factors associated with tenofovir diphosphate concentrations in dried blood spots in persons living with HIV.

Coyle RP, Morrow M, Coleman SS, Gardner EM, Zheng JH, Ellison L, Bushman LR, Kiser JJ, MaWhinney S, Anderson PL, Castillo-Mancilla JR.

J Antimicrob Chemother. 2020 Mar 24. pii: dkaa070. doi: 10.1093/jac/dkaa070. PMID: 32211787

 

Intrahepatic Viral Kinetics during Direct-Acting Antivirals for Hepatitis C in HIV Co-infection:The ACTG A5335S Substudy.

Balagopal A, Smeaton LM, Quinn J, Venuto CS, Morse GD, Vu V, Alston-Smith B, Cohen DE, Santana-Bagur JL, Anthony DD, Sulkowski MS, Wyles DL, Talal AH.

J Infect Dis. 2020 Mar 23. pii: jiaa126. doi: 10.1093/infdis/jiaa126.  PMID: 32201883

 

Advances in Long-Acting Agents for the Treatment of HIV Infection.

Rana AI, Castillo-Mancilla JR, Tashima KT, Landovitz RL.

Drugs. 2020 Mar 16. doi: 10.1007/s40265-020-01284-1.  PMID: 32180205

 

Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis.

Rodriguez-Morales AJ, Cardona-Ospina JA, Gutiérrez-Ocampo E, Villamizar-Peña R, Holguin-Rivera Y, Escalera-Antezana JP, Alvarado-Arnez LE, Bonilla-Aldana DK, Franco-Paredes C, Henao-Martinez AF, Paniz-Mondolfi A, Lagos-Grisales GJ, Ramírez-Vallejo E, Suárez JA, Zambrano LI, Villamil-Gómez WE, Balbin-Ramon GJ, Rabaan AA, Harapan H, Dhama K, Nishiura H, Kataoka H, Ahmad T, Sah R; Latin American Network of Coronavirus Disease 2019-COVID-19 Research (LANCOVID-19). Electronic address: https://www.lancovid.org.

Travel Med Infect Dis. 2020 Mar 13:101623. doi: 10.1016/j.tmaid.2020.101623.  Review. PMID: 32179124

 

The Struggling Infectious Diseases Fellow: Remediation Challenges and Opportunities.

Melia MT, Paez A, Reid G, Chirch LM, Luther VP, Blackburn BG, Perez F, Abdoler E, Kaul DR, Rehm S, Harik N, Barsoumian A, Person AK, Yun H, Beckham JD, Boruchoff S, Cariello PF, Cutrell JB, Graber CJ, Lee DH, Maziarz E, Paras ML, Razonable RR, Ressner R, Chen A, Chow B, Escota G, Herc E, Johnson A, Maves RC, Nnedu O, Clauss H, Kulkarni P, Pottinger PS, Serpa JA, Bhowmick T, Bittner M, Wooten D, Casanas B, Shnekendorf R, Blumberg EA.

Open Forum Infect Dis. 2020 Feb 18;7(3):ofaa058. doi: 10.1093/ofid/ofaa058. eCollection 2020 Mar. Review. PMID: 32166097

 

Serial Sputum Induction in Nontuberculous Mycobacterial Pulmonary Disease.

Holt MR, Kasperbauer SH, Daley CL.

Eur Respir J. 2020 Mar 12. pii: 1902196. doi: 10.1183/13993003.02196-2019. PMID: 32165404

 

Treatment of advanced AIDS-associated Kaposi sarcoma in resource-limited settings: a three-arm, open-label, randomised, non-inferiority trial.

Krown SE, Moser CB, MacPhail P, Matining RM, Godfrey C, Caruso SR, Hosseinipour MC, Samaneka W, Nyirenda M, Busakhala NW, Okuku FM, Kosgei J, Hoagland B, Mwelase N, Oliver VO, Burger H, Mngqibisa R, Nokta M, Campbell TB, Borok MZ; A5263/AMC066 protocol team.

Lancet. 2020 Mar 5. pii: S0140-6736(19)33222-2. doi: 10.1016/S0140-6736(19)33222-2. PMID: 32145827

 

Gastrointestinal symptoms in relation to quality of life after metabolic surgery in adolescents.

Dewberry L, Khoury J, Schmiege S, Jenkins T, Boles R, Inge T.

Surg Obes Relat Dis. 2020 Jan 3. pii: S1550-7289(19)31163-3. doi: 10.1016/j.soard.2019.12.025. PMID: 32122816

 

Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout.

Klück V, van Deuren RC, Cavalli G, Shaukat A, Arts P, Cleophas MC, CriÈ™an TO, Tausche AK, Riches P, Dalbeth N, Stamp LK, Hindmarsh JH, Jansen TLTA, Janssen M, Steehouwer M, Lelieveld S, van de Vorst M, Gilissen C, Dagna L, Van de Veerdonk FL, Eisenmesser EZ, Kim S, Merriman TR, Hoischen A, Netea MG, Dinarello CA, Joosten LA.

Ann Rheum Dis. 2020 Apr;79(4):536-544. doi: 10.1136/annrheumdis-2019-216233. Epub 2020 Feb 29. PMID: 32114511

 

Use of Procalcitonin to Guide Discontinuation of Antimicrobial Therapy in Patients with Persistent Intra-Abdominal Collections: A Case Series. Motoa G, Pate A, Franco-Paredes C, Chastain DB, Henao-Martínez AF, Hojat L. Case Rep Infect Dis. 2020 Jan 9;2020:6342180. doi: 10.1155/2020/6342180. eCollection 2020.PMID: 32158570

COVID-19 in Latin America: The implications of the first confirmed case in Brazil.
Rodriguez-Morales AJ, Gallego V, Escalera-Antezana JP, Méndez CA, Zambrano LI, Franco-Paredes C, Suárez JA, Rodriguez-Enciso HD, Balbin-Ramon GJ, Savio-Larriera E, Risquez A, Cimerman S. Travel Med Infect Dis. 2020 Feb 29:101613. doi: 10.1016/j.tmaid.2020.101613. [Epub ahead of print] No abstract available. PMID: 32126292

Antibiotic Prescribing Patterns for Acute Otitis Media for Children 2 Years and Older.
Frost HM, Becker LF, Knepper BC, Shihadeh KC, Jenkins TC. J Pediatr. 2020 Feb 25. pii: S0022-3476(20)30116-5. doi: 10.1016/j.jpeds.2020.01.045. [Epub ahead of print] PMID: 32111379 [PubMed - as supplied by publisher]

Antiretroviral therapy initiation is associated with decreased visceral and subcutaneous adipose tissue density in people living with HIV.
Debroy P, Lake JE, Moser C, Olefsky M, Erlandson KM, Scherzinger A, Stein JH, Currier JS, Brown TT, McComsey GA. Clin Infect Dis. 2020 Feb 28. pii: ciaa196. doi: 10.1093/cid/ciaa196. [Epub ahead of print]. PMID: 32107532

Risk Factors for Weight Gain Following Switch to Integrase Inhibitor-Based Antiretroviral Therapy.
Lake JE, Wu K, Bares SH, Debroy P, Godfrey C, Koethe JR, McComsey GA, Palella FJ Jr, Tassiopoulos K, Erlandson KM; ACTG A5322 Study Team. Clin Infect Dis. 2020 Feb 26. pii: ciaa177. doi: 10.1093/cid/ciaa177. [Epub ahead of print] PMID: 32099991

The Impact of a Structured, Supervised Exercise Program on Daily Step Count in Sedentary Older Adults With and Without HIV.
Stabell AC, Wilson M, Jankowski CM, MaWhinney S, Erlandson KM. J Acquir Immune Defic Syndr. 2020 Feb 20. doi: 10.1097/QAI.0000000000002326. [Epub ahead of print] PMID: 32084050

Bile Acid Sequestration Reverses Liver Injury and Prevents Progression of NASH in Western Diet-Fed Mice.
Takahashi S, Luo Y, Ranjit S, Xie C, Libby AE, Orlicky DJ, Dvornikov A, Wang XX, Myakala K, Jones BA, Bhasin K, Wang D, McManaman JL, Krausz KW, Gratton E, Ir D, Robertson CE, Frank DN, Gonzalez FJ, Levi M. J Biol Chem. 2020 Feb 19. pii: jbc.RA119.011913. doi: 10.1074/jbc.RA119.011913. [Epub ahead of print] PMID: 32075905

Guidelines for the treatment of latent tuberculosis infection: Recommendations from the National Tuberculosis Controllers Association and CDC, 2020.
Sterling TR, Njie G, Zenner D, Cohn DL, Reves R, Ahmed A, Menzies D, Horsburgh CR,  Crane CM, Burgos M, LoBue P, Winston CA, Belknap R.   MMWR Recomm Rep 2020;69(No. RR-1):1–11.

A 31-year-old Micronesian Man With Shoulder Fungating Mass.
Canfield GS, Bock A, Mann S, Zimmer S, Somerset H, Franco-Paredes C, Wilson CC, Metter RB. Clin Infect Dis. 2020 Feb 14;70(5):973-975. doi: 10.1093/cid/ciz591. No abstract available.

Systemic Expression of a Viral RdRP Protects Against Retrovirus Infection and Disease.
Miller CM, Barrett BS, Chen J, Morrison JH, Radomile C, Santiago ML, Poeschla EM. J Virol. 2020 Feb 12. pii: JVI.00071-20. doi: 10.1128/JVI.00071-20. [Epub ahead of print]

A deadly feast: Elucidating the burden of orally acquired acute Chagas disease in Latin America - Public health and travel medicine importance.
Franco-Paredes C, Villamil-Gómez WE, Schultz J, Henao-Martínez AF, Parra-Henao G, Rassi A Jr, Rodríguez-Morales AJ, Suarez JA. Travel Med Infect Dis. 2020 Jan 29:101565. doi: 10.1016/j.tmaid.2020.101565. [Epub ahead of print] Review.

Preventing paralytic polio caused by vaccine-derived poliovirus type 2.
Franco-Paredes C, Santos-Preciado JI, Henao-Martinez AF, Rodriguez-Morales AJ, Carrasco P.< Lancet Infect Dis. 2020 Jan;20(1):21-22. doi: 10.1016/S1473-3099(19)30692-9. No abstract available. PMID:31 876491

Quantifying HIV-1-Mediated Gut CD4+ T Cell Death in the Lamina Propria Aggregate Culture (LPAC) Model.
Dillon, S. M., Guo, K., Castleman, M. J., Santiago, M. L. and Wilson, C. C. (2020). Bio-protocol. 10(2): e3486. DOI: 10.21769/BioProtoc.3486.

End-of-Life Planning Prior to Death Among People Living With HIV.
Abdo M, Ressler A, MaWhinney S, Jankowski C, Johnson SC, Erlandson KM. J Assoc Nurses AIDS Care. 2020 Feb 13. doi: 10.1097/JNC.0000000000000162. [Epub ahead of print]

Can gut microbiota of men who have sex with men influence HIV transmission?

Coleman SL, Neff CP, Li SX, Armstrong AJS, Schneider JM, Sen S, Fennimore B, Campbell TB, Lozupone CA, Palmer BE. Gut Microbes. 2020 Feb 10:1-10. doi: 10.1080/19490976.2019.1700756. [Epub ahead of print]

Physical activity and exercise to improve cardiovascular health for adults living with HIV.
Ozemek C, Erlandson KM, Jankowski CM. Prog Cardiovasc Dis. 2020 Jan 31. pii: S0033-0620(20)30027-X. doi: 10.1016/j.pcad.2020.01.005. [Epub ahead of print] Review.

Identification of Novel Genes and Biological Pathways That Overlap in Infectious and Nonallergic Diseases of the Upper and Lower Airways Using Network Analyses.
Baschal EE, Larson ED, Bootpetch Roberts TC, Pathak S, Frank G, Handley E, Dinwiddie J, Moloney M, Yoon PJ, Gubbels SP, Scholes MA, Cass SP, Jenkins HA, Frank DN, Yang IV, Schwartz DA, Ramakrishnan VR, Santos-Cortez RLP. Front Genet. 2020 Jan 17;10:1352. doi: 10.3389/fgene.2019.01352. eCollection 2019.

Falling Through the Cracks: Risk Factors for Becoming Lost to HIV Care After Incarceration in a Southern Jail.
Tiruneh YM, Li X, Bovell-Ammon B, Iroh P, Flanigan TP, Montague BT, Rich JD, Nijhawan AE. AIDS Behav. 2020 Jan 31. doi: 10.1007/s10461-020-02803-7. [Epub ahead of print]

Editorial: Forging new frontiers in HIV and aging.
Masters MC, Erlandson KM. Curr Opin HIV AIDS. 2020 Mar;15(2):81-82. doi: 10.1097/COH.0000000000000610. No abstract available.

Fusobacterium necrophorum subsp. necrophorum Liver Abscess with Pylephlebitis: An Abdominal Variant of Lemierre's Syndrome.
Radovanovic N, Dumic I, Veselinovic M, Burger S, Milovanovic T, Nordstrom CW, Niendorf E, Ramanan P. Case Rep Infect Dis. 2020 Jan 13;2020:9237267. doi: 10.1155/2020/9237267. eCollection 2020.

Nutrimetabolomics reveals food-specific compounds in urine of adults consuming a DASH-style diet.
Reisdorph NA, Hendricks AE, Tang M, Doenges KA, Reisdorph RM, Tooker BC, Quinn K, Borengasser SJ, Nkrumah-Elie Y, Frank DN, Campbell WW, Krebs NF. Sci Rep. 2020 Jan 24;10(1):1157. doi: 10.1038/s41598-020-57979-8.

HIV, aging, and adherence: an update and future directions.
Mann SC, Castillo-Mancilla JR. Curr Opin HIV AIDS. 2020 Mar;15(2):134-141. doi: 10.1097/COH.0000000000000615.

Plasma and antibody glycomic biomarkers of time to HIV rebound and viral setpoint.
Giron LB, Papasavvas E, Azzoni L, Yin X, Anzurez A, Damra M, Mounzer K, Kostman JR, Sanne I, Firnhaber CS, Tateno H, Liu Q, Montaner LJ, Abdel-Mohsen M. AIDS. 2020 Jan 17. doi: 10.1097/QAD.0000000000002476. [Epub ahead of print]

Obese adolescents with PCOS have altered biodiversity and relative abundance in gastrointestinal microbiota.
Jobira B, Frank DN, Pyle L, Silveira LJ, Kelsey MM, Garcia-Reyes Y, Robertson CE, Ir D, Nadeau KJ, Cree-Green M. J Clin Endocrinol Metab. 2020 Jan 23. pii: dgz263. doi: 10.1210/clinem/dgz263. [Epub ahead of print]

Roles of Candida albicans Mig1 and Mig2 in glucose repression, pathogenicity traits, and SNF1 essentiality.
Lagree K, Woolford CA, Huang MY, May G, McManus CJ, Solis NV, Filler SG, Mitchell AP. PLoS Genet. 2020 Jan 21;16(1):e1008582. doi: 10.1371/journal.pgen.1008582. eCollection 2020 Jan.

Liver Transplantation for Decompensated Cirrhosis Secondary to Telomerase Reverse Transcriptase (TERT) Mutation.
Kolb JM, Conzen K, Wachs M, Crossno J Jr, McMahon B, Abidi MZ, Pomfret EA, Kriss M. Hepatology. 2020 Jan 14. doi: 10.1002/hep.31111. [Epub ahead of print]

HIV infection does not alter interferon α/β receptor 2 expression on mucosal immune cells.
Ickler J, Francois S, Widera M, Santiago ML, Dittmer U, Sutter K. PLoS One. 2020 Jan 14;15(1):e0218905. doi: 10.1371/journal.pone.0218905. eCollection 2020.

A multicenter randomized placebo controlled trial of rifampin to reduce pedal amputations for osteomyelitis in veterans with diabetes (VA INTREPID).
Bessesen MT, Doros G, Henrie AM, Harrington KM, Hermos JA, Bonomo RA, Ferguson RE, Huang GD, Brown ST. BMC Infect Dis. 2020 Jan 8;20(1):23. doi: 10.1186/s12879-019-4751-3.

Higher acuity resource utilization with older age and poorer HIV control in adolescents and young adults in the HIV Research Network.
Neilan AM, Lu F, Gebo KA, Diaz-Reyes R, Huang M, Parker RA, Karalius B, Patel K, Voss C, Ciaranello AL, Agwu AL. J Acquir Immune Defic Syndr. 2020 Jan 3. doi: 10.1097/QAI.0000000000002280. [Epub ahead of print]

What is the collective effect of aging and HIV on the gut microbiome?
Dillon SM, Wilson CC. Curr Opin HIV AIDS. 2020 Mar;15(2):94-100. doi: 10.1097/COH.0000000000000611.

Hantavirus Infection with Renal Failure and Proteinuria, Colorado, USA, 2019.
Chand S, Thapa S, Kon S, Johnson SC, Poeschla EM, Franco-Paredes C, Rodríguez-Morales AJ, Mattar S, Henao-Martínez AF. Emerg Infect Dis. 2020 Feb;26(2):383-385. doi: 10.3201/eid2602.191349. PMID: 31961310

 

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