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The mission of the RNA Bioscience Initiative (RBI) is to cultivate a vibrant center of discovery and innovation in RNA biology, informatics, diagnostics, and therapy. Our goal is to provide a fluid pipeline from basic to clinical RNA research at the Anschutz Medical Campus.
Autumn 2022Yale University researchers took advantage of single-cell RNA sequencing technology to determine what makes the human brain different from our closest primate relatives. They discovered that microglia, a type of immune cell found only in the central nervous system, is specific to humans. Furthermore, the team found that these microglia express the gene FOXP2; FOXP2 expression has been associated with both language acquisition and neurological diseases.
Autumn 2022Researchers at Ohio State University recently identified 5000 types of RNA viruses in the world's oceans, most of which were previously unknown. Importantly, at least 11 of the newly discovered virus infect plankton that play a role in the "carbon pump" that sequesters CO2 on the sea floor. Researchers predict that in the future manipulation of these viruses may be used to improve CO2 capture.
RNA polymerase travels along each gene from beginning to end and makes an RNA copy of the genetic code. New research from the Bentley lab shows that the RNA polymerase likes to “take a break” or “pause” in a zone at the beginning of genes. Control of this pausing likely impacts how genetic information is accessed and used to control living cells.
The RBI has made CU Anschutz a clear hub of RNA biology expertise, raising the status of the university and its researchers in the eyes of scientists at institutions around the country and the world. The RBI sets CU Anschutz up as a leader in the exciting and groundbreaking field of RNA biology.
Amy Campbell, PhD
RBI Co-Director, David Bentley, PhD, was interviewed by 9News reporter Anusha Roy and featured on Next with Kyle Clark. In this piece Dr. Bentley expertly describes the future of mRNA technology and its possible therapeutic uses beyond the COVID vaccine.