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The mission of the RNA Bioscience Initiative (RBI) is to cultivate a vibrant center of discovery and innovation in RNA biology, informatics, diagnostics, and therapy. Our goal is to provide a fluid pipeline from basic to clinical RNA research at the Anschutz Medical Campus.
January 6, 2022
Moderna, Inc. is rapidly expanding its catalog of mRNA vaccines. The latest candidate that has advanced to clinical trials is mRNA-1189, which targets the Epstein-Barr virus (EBV). EBV is a major cause of infectious mononucleosis in young adults, and has been linked to other illnesses, including Burkitt's Lymphoma.
January 5, 2022Pre-eclampsia is a leading cause of pregnancy-related morbidity and mortality. New research published in the journal Nature demonstrates that analysis of RNA present in maternal blood can predict women at risk for pre-eclampsia early in pregnancy before it becomes a threat.
CONGRATULATIONS Dr. Ramos! This award acknowledges exceptional contributions to RNA science by a trainee who is underrepresented in biomedical research. Jillian was recognized for her "contributions to understanding tRNA structure and function, combined with her outreach, mentoring and education activities."Read More
December 15, 2021
The RBI Summer Internship Program is a PAID, 10-week hands-on, mentored research opportunity for undergraduates who want to gain real-world laboratory experience in RNA biology, chemistry, biochemistry, genomics, and bioinformatics.Apply Now
CONGRATULATIONS Dr. Swain! This grant from NIH-NIDCR, titled N6-methyladenosine in Candida white-opaque switching and oral infection, will provide an additional 2 years of postdoctoral support ($90,000 per year) AND $249,000/year for 3 years upon starting an independent lab as a faculty member.Read More
This study published in the journal Science (DOI: 10.1126/science.abe8526) reveals how viral RNAs can use molecular mimicry and shape-shifting to hijack host cell machinery, and highlights the power of cryo-EM to visualize small, conformationally dynamic structured RNAs. Congratulations to Steve and his co-authors Maddie Sherlock, Andrea MacFadden, and Jeff Kieft!
A comprehensive evaluation of the RBI Pilot Grant Program recently revealed a success story beyond our wildest dreams. Investigators were able to leverage data from their RBI pilot grant awards into $56,540,451 worth of additional grant funding. This represents a return on investment (ROI) of 2172%!!! Special thanks to the RBI Informatics Fellows and the entire RBI team for their hard work!Read More
The RBI has made CU Anschutz a clear hub of RNA biology expertise, raising the status of the university and its researchers in the eyes of scientists at institutions around the country and the world. The RBI sets CU Anschutz up as a leader in the exciting and groundbreaking field of RNA biology.
Amy Campbell, PhD