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The mission of the RNA Bioscience Initiative (RBI) is to cultivate a vibrant center of discovery and innovation in RNA biology, informatics, diagnostics, and therapy. Our goal is to provide a fluid pipeline from basic to clinical RNA research at the Anschutz Medical Campus.
A recent study published in Nature provides evidence that RNA and peptides co-evolved supporting the idea that primordial life originated without DNA. In the laboratory, researchers from Germany demonstrate that synthetic RNAs, generated using rare nucleosides, can bind amino acids and form short peptides (~ 15 amino acids long). This discovery lays the groundwork for an RNA-protein world.
June 2022Researchers at Hokkaido University in Sapporo, Japan have collaborated with astrochemists at NASA's Goddard Space Flight Center to detect and measure the presence of nucleobases in meteorites. Previous studies have demonstrated that meteorites can contain bio-sugars including ribose, as well as nucleobases adenine, guanine, and uracil. Using new, more sensitive extraction techniques the current study, published in Nature Communications, additionally demonstrates the presence of cytosine and thymine, possibly indicating that the molecular ingredients necessary for life may be extraterrestrial in origin.
We encourage you to watch the latest video from the RNA Bioscience Initiative. In this video RBI co-founder and co-director, Dr. David Bentley, deftly explains the nature of RNA in simple, accessible terms. Please share this video with friends and family
and help us expand understanding of RNA and RNA research to a broader audience.
The RBI has made CU Anschutz a clear hub of RNA biology expertise, raising the status of the university and its researchers in the eyes of scientists at institutions around the country and the world. The RBI sets CU Anschutz up as a leader in the exciting and groundbreaking field of RNA biology.
Amy Campbell, PhD
RBI Co-Director, David Bentley, PhD, was interviewed by 9News reporter Anusha Roy and featured on Next with Kyle Clark. In this piece Dr. Bentley expertly describes the future of mRNA technology and its possible therapeutic uses beyond the COVID vaccine.