A Slice of RNA
The objective of A Slice of RNA is to foster a collaborative environment for students, post-docs and faculty to share their research with the ever-expanding RNA community of Colorado. Hosted by the Colorado RNA Club in collaboration with the RNA Bioscience Initiative at CU Anschutz, this event includes PIZZA LUNCH and takes place approximately 4 times between September and May; event location varies.
Schedule
| Date | Presenters | Lab | Institution | Title |
| September 19, 2023 | ||||
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| October 17, 2023 | ||||
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| February XX, 2024 | ||||
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| March 19, 2024 | ||||
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| Date | Presenters | Lab | Institution | Title |
| September 20, 2022 | Allison Porman Swain | Johnson Lab | CU Anschutz | Mechanisms of the m6A RNA modification in lncRNA HOTAIR and Candida albicans |
| Maddie Sherlock | Kieft Lab | CU Anschutz | Structure and mechanism of translation reinitiation by viral RNAs | |
| Scott Horowitz | Horowitz Lab | University of Denver | Chaperoning proteins with RNA | |
| Christopher Phiel | Phiel Lab | CU Denver | Embryonic stem cell pluripotency and mRNA | |
| October 18, 2022 | Tai Montgomery | Montgomery Lab | Colorado State University | The making of a microRNA |
| Grant Lo | Taliaferro Lab | CU Anschutz | Uncovering the localization of ASPM RNA to the centrosome | |
| Ariel Lucas Eraso | Taatjes Lab | CU Boulder | Vitro-seq: a new method to study transcription | |
| Anthony Khong | Parker Lab | CU Boulder | Stress granules promote chemoresistance by triggering cellular quiescence | |
| February 21, 2023 | Andres Ramos | University College London | Molecular basis of non-canonical m6A regulation | |
| Roy Parker | CU-Boulder | RNP granules in human disease | ||
| March 21, 2023 | Savannah Spradlin | Bately Lab | CU-Boulder | Structural basis of promiscuous small-molecule binding by a bacterial riboswitch |
| Laura White | RBI Fellow | CU-Anschutz | Direct detection of RNA repair with nanopore sequencing | |
| Alex Whiteley | CU-Boulder | When worlds collide: mRNA features encode protein fate |
| Date | Presenters | Lab | Institution | Title |
| September 21, 2021 | Ted Ewachiw | Bradley Olwin | CU Boulder | TBD |
| Huy Vo | Brian Munsky | Colorado State University | Maximizing information in single-cell experiments under measurement uncertainties | |
| Ning Zhao | Tim Stasevich | Colorado State University | Imaging the life cycle of proteins in situ in real time | |
| October 19, 2021 | Steve Bonilla | Jeff Kieft | CU Anschutz | A viral RNA uses conformational changes of a dynamic tRNA-like structure to hijack cellular machinery |
| Meghan Lybecker | Meghan Lybecker | UCCS | c-di-GMP regulates the activity of an RNA chaperone in the Lyme disease spirochete | |
| Kathryn Walters | Neelanjan Mukherjee | CU Anschutz | MSI2 potentiates the AngII-stimulation response and human steroidogenesis | |
| November 16, 2021 | Cormac Lucas | Tem Morrison | CU Anschutz | Lymph node interactions with chikungunya virus |
| James Burke | Roy Parker | CU Boulder | Cytoplasmic RNA decay regulates nuclear host/viral mRNA biogenesis during pathogenic viral infections | |
| Samuel Hunter | Robin Dowell | CU Boulder | RNA and aneuploidy: How trisomy 21 affects RNA dosage | |
| December 21, 2021 | Devin Wahl | Healthspan Biology Lab | Colorado State University | TBD |
| Michael Cortazar Osorio | Sujatha Jagannathan | CU Anschutz | Saturation genome editing as a tool to understand the rules of nonsense-mediated mRNA decay | |
| Frank Lee | Scott Alper | National Jewish Health | RNA binding proteins that regulate Alternative Splicing of MyD88, a Critical Adaptor Protein in Innate Immunity | |
| January 18, 2022 | Meg Filbin | Meg Filbin | MSU Denver | Ribosome regulation by small disordered proteins |
| Joe Giovinazzo | Rui Zhao | CU Anschutz | How does a small molecule modulate 5' splice site recognition? | |
| Hossein Shenasa | David Bentley | CU Anschutz | Expanding the window of opportunity model for co-transcrtiptional splicing | |
| February 15, 2022 | Raeann Goering | Matthew Taliaferro | CU Anschutz | Mechanisms of RNA localization transcend cell morphology |
| Nick Lammer | Deborah Wuttke | CU Boulder | Defining the extent and function of glucocorticoid receptor-RNA binding | |
| Linda van Dyk | Linda van Dyk | CU Anschutz | Shared functions of sequence divergent viral ncRNAs | |
| March 15, 2022 | Jiarui Song | Tom Cech | CU Boulder | Cryo-EM structure reveals G-quadruplex RNA-mediated PRC2 dimerization |
| Robert Williams | Erin Nishimura | Colorado State University | The C. elegans intestine transcription factor ELT-2 positively and negatively regulates target genes | |
| Ashleigh Keller | Horizon Discovery | Horizon Discovery | Development of a novel dCas9 fusion protein for robust CRISPRi-mediated transcriptional repression | |
| April 19, 2022 | Chrysa Latrick | Editas Medicine | Editas Medicine | An RNA detective story: elucidating the impact of RNA secondary structure on RNP behavior |
| Michael Smallegan | John Rinn | CU Boulder | The lncRNA Firre functions as a transcriptional activator | |
| Wayne Hemphill | Tom Cech | CU Boulder | Inter-polynucleotide transfer is intrinsic to PCR2 and supports an RNA-chromatin hand-off model | |
| May 17, 2022 | Neelanjan Mukherjee | Neelanjan Mukherjee | CU Anschutz | Translational research: Treating Multiple Myeloma with Omacetaxine |
| Giulia Corbet | Roy Parker | CU Boulder | dsRNA-induced condensation modulates PKR activation | |
| Luis Aguilera | Brian Munsky | Colorado State University | Using single-molecule fluorescence microscopy and computational modeling to understand gene expression |
| Date | Presenters | Lab | Institution | Title |
| September 15, 2020 | Tim-Michael Decker | Dylan Taatjes | CU Boulder | Targeted degradation of transcription elongation factor SPT5 using the dTAG system |
| Kelsey Nassar | Aik-Choon Tan | CU Anschutz | Transcriptomic analysis of mutant SF3B1 and its effects on mucosal melanoma oncogenesis | |
| O'Neil Wiggan | Neil Wiggan | Colorado State University | Real-time imaging of transcription and translation from an endogenous gene | |
| October 20, 2020 | Frank Lee | Scott Alper | National Jewish Health | Regulating MyD88 alternative splicing in mouse macrophages |
| Megan Cerny | Amanda Charlesworth | CU Denver | Differential expression of Oct paralogs during early development of Xenopus laevis | |
| Conner Langeberg | Jeffrey Kieft | CU Anschutz | A conserved class of hystidylatable viral tRNA mimics | |
| November 17, 2020 | Gongyi Zhang | Gongyi Zhang | National Jewish Health | RNA Polymerase II pausing regulation in higher eukaryotes |
| Traci Lyons | Traci Lyons | CU Anschutz | Insights into pregnancy-related breast cancer through RNA analysis | |
| Charlotte Cialek | Tim Stasevich | CSU | Visualizing dynamic tethering of Argonaute to single mRNA in live human cells | |
| December 15, 2020 | Matthew Taylor | Matthew Taylor | CU Anschutz | Reading the tea leaves of the human cardiovascular transcriptome |
| Parker Nichols | Beat Vogeli | CU Anschutz | A-Z junction formation in Alu RNAs: A role for the Z-RNA binding domain of ADAR1 | |
| Robert Batey | Robert Batey | CU Boulder | Riboswitches: Finding the hidden messages in the message | |
| January 19, 2021 | Evan Lester | Roy Parker | CU Boulder | Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components |
| Eugenia Olesnicky | Eugenia Olesnicky Killian | UCCS | Tissue specific roles for the splicing factor Caper in aging and development | |
| Rytis Prekeris | Rytis Prekeris | CU Anschutz | The role of mid-body assocoated RNA in regulating cell proliferation and differentiation | |
| February 16, 2021 | Ankita Arora | Matthew Taliaferro | CU Anschutz | Identifying RNA localization targets of TDP-43 using functional genomics |
| Sujatha Jagannathan | Sujatha Jagannathan | CU Anschutz | When cells' garbage disposal fails: Compromised RNA quality control in the human muscle disease FSHD | |
| Jennyfer M Mitchell | Jennyfer M Mitchell | CU Anschutz | alx3 is a key player during early patterning of neurocranial elements in zebrafish | |
| March 16, 2021 | Christian Much | John Rinn | CU Boulder | Spatiotemporal dynamics of gene regulation by the lncRNA Firre |
| Olve Peersen | Olve Peersen | CSU | Co-folding and membrane binding of poliovirus P3 polyprotein precursors | |
| David Bentley | David Bentley | CU Anschutz | Transcription speed: why it matters and how to control it | |
| April 20, 2021 | Alicia Cutler | Brad Olwin | CU Boulder | There and back again a stem cell self-renewal tale |
| Raeann Goering | Matthew Taliaferro | CU Anschutz | Mechanisms of RNA localization that transcend cell morphology | |
| Richard Davis | Richard Davis | CU Anschutz | Argonautes, small RNAs and programmed DNA elimination: A journey and saga | |
| May 18, 2021 | Jeff Mayfield | Amanda Charlesworth | CU Denver | TBD |
| Rachel Jones | Jeffrey Kieft | CU Anschutz | Repeating history: New sequences and tertiary interactions create the same important 3-D features in divergent flavivrus xrRNAs | |
| Hossein Shenasa | David Bentley | CU Anschutz | Molecular insights into splice site selection |
| Date | Presenters | Lab | Institution | Title |
| September 17, 2019 | Roman Iwasaki | Robert Batey | CU Boulder | A Cas13-based assay rapidly quantifies transcription and enables biosensing of small molecules |
| Craig Forester | Craig Forester | CU Anschutz | Dissecting specific translational activation in early hematopoiesis | |
| Christopher Phiel | Christopher Phiel | CU Denver | Stem cell pluripotency, metabolism, and m6A | |
| Michael Cortázar | Sujatha Jagannathan | CU Anschutz | Transcription elongation and termination: the sitting-duck torpedo model | |
| October 15, 2019 | Tom Santangelo | Colorado State University | Abundant and diverse RNA modifications supporting thermophily in the Archaea | |
| Rui Zhao | Rui Zhao | CU Anschutz | Cryo-EM structure of spliceosomal E complex and biochemical analyses reveal a unified mechanism for intron definition, exon definition, and back-splicing | |
| Yicheng Long | Tom Cech | CU Boulder | RNA-protein interactions regulate epigenetic silencing | |
| Stephanie Moon | Roy Parker | CU Boulder | Coupling of translational quality control and mRNA targeting to stress granules | |
| November 19, 2019 | Esther Braselmann | Esther Braselmann | CU Boulder | Illuminating RNA dynamics in mammalian cells with the Riboglow platform |
| Devin Tauber | Roy Parker | CU Boulder | Modulation of RNA condensation by the DEAD-box protein eIF4A | |
| Olivia Rissland | Olivia Rissland | CU Anschutz | Connections between translation and mRNA decay | |
| Allison Swain | Aaron Johnson | CU Anschutz | m6A RNA modifications regulate lncRNA HOTAIR in breast cancer | |
| December 10, 2019 | John Rohloff | Industry | Somalogic | Chemically-modified DNA aptamers |
| Brenna Dennison | Katherine Fantauzzo | CU Anschutz | Srsf3-mediated alternative RNA splicing downstream of PDGFRα signaling in the palatal mesenchyme | |
| Yuanyuan Xie | Edward Chuong | CU Boulder | Harnessing transposon-derived dsRNA to kill cancer cells | |
| Cecilia Levandowski | Dylan Taatjes | CU Boulder | How does ∆40p53 alter p53 function? | |
| January 21, 2020 | Joseph Cardiello | R Dowell & MA Allen | CU Boulder | Investigating the effects of Down syndrome on the induction of heat shock responsive gene mRNAs across a cellular population |
| Siddharth Shukla | Roy Parker | CU Boulder | ||
| Claire Gillette | Tania Reis | CU Anschutz | RNA-binding proteins and fat storage homeostasis: a tale of fat flies | |
| James Till | Andres Vazquez-Torres | CU Anschutz | Linking nitrosative stress-induced metabolic adaptations to aminoglycoside tolerance | |
| April 28, 2020 | Danielle Bilodeau | Olivia Rissland | CU Anschutz | Using long-read sequencing to validate RNA cleavage events in Giardia lamblia |
| Tom Evans | Tom Evans | CU Anschutz | Genetic surprises: novel Sm family ncRNAs control developmental recovery from starvation in C. elegans | |
| July 21, 2020 | Otto Kletzien | Robert Batey | CU Boulder | hnRNPU RGG is part of a larger RNA-binding domain |
| Kevin Hemphill | Industry | Horizon Discovery | Chemical synthesis of long RNA for CRISPR mediated gene activation (CRISPRa) |
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