Evenings with RNA



The objective of Evenings with RNA is to foster a collaborative environment for students, post-docs and faculty to share their research with the ever-expanding RNA community of Colorado. Hosted by the Colorado RNA Club in collaboration with the RNA Bioscience Initiative at CU Anschutz, this event takes place at 3pm on the 3rd Tuesday of each month, September through May; event location varies.

Organizers

Shelby Lennon (CU Boulder)
shelby.lennon@colorado.edu

Roberto Castro-Gutierrez  (CU Anschutz)
roberto.castrogutierrez@cuanschutz.edu


Evenings with RNA events are currently being hosted in hybrid format with both in-person and Zoom options.

Evenings with RNA- March 15, 2022

Schedule

DatePresentersLabInstitutionTitle
September 21, 2021Ted EwachiwBradley OlwinCU BoulderTBD
Huy VoBrian MunskyColorado State UniversityMaximizing information in single-cell experiments under measurement uncertainties
Ning ZhaoTim StasevichColorado State UniversityImaging the life cycle of proteins in situ in real time
October 19, 2021Steve BonillaJeff KieftCU AnschutzA viral RNA uses conformational changes of a dynamic tRNA-like structure to hijack cellular machinery
Meghan LybeckerMeghan LybeckerUCCSc-di-GMP regulates the activity of an RNA chaperone in the Lyme disease spirochete
Kathryn WaltersNeelanjan MukherjeeCU AnschutzMSI2 potentiates the AngII-stimulation response and human steroidogenesis
November 16, 2021Cormac LucasTem MorrisonCU AnschutzLymph node interactions with chikungunya virus
James BurkeRoy ParkerCU BoulderCytoplasmic RNA decay regulates nuclear host/viral mRNA biogenesis during pathogenic viral infections
Samuel HunterRobin DowellCU BoulderRNA and aneuploidy: How trisomy 21 affects RNA dosage
December 21, 2021Devin WahlHealthspan Biology LabColorado State UniversityTBD
Michael Cortazar OsorioSujatha JagannathanCU AnschutzSaturation genome editing as a tool to understand the rules of nonsense-mediated mRNA decay
Frank LeeScott AlperNational Jewish HealthRNA binding proteins that regulate Alternative Splicing of MyD88, a Critical Adaptor Protein in Innate Immunity
January 18, 2022Meg FilbinMeg FilbinMSU DenverRibosome regulation by small disordered proteins
Joe GiovinazzoRui ZhaoCU AnschutzHow does a small molecule modulate 5' splice site recognition?
Hossein ShenasaDavid BentleyCU AnschutzExpanding the window of opportunity model for co-transcrtiptional splicing
February 15, 2022Raeann GoeringMatthew TaliaferroCU Anschutz

Mechanisms of RNA localization transcend cell morphology

Nick LammerDeborah WuttkeCU Boulder

Defining the extent and function of glucocorticoid receptor-RNA binding

Linda van DykLinda van DykCU Anschutz

Shared functions of sequence divergent viral ncRNAs

March 15, 2022Jiarui SongTom CechCU Boulder

Cryo-EM structure reveals G-quadruplex RNA-mediated PRC2 dimerization

Robert WilliamsErin NishimuraColorado State University

The C. elegans intestine transcription factor ELT-2 positively and negatively regulates target genes

Ashleigh KellerHorizon DiscoveryHorizon DiscoveryDevelopment of a novel dCas9 fusion protein for robust CRISPRi-mediated transcriptional repression
April 19, 2022Chrysa LatrickEditas MedicineEditas Medicine

An RNA detective story: elucidating the impact of RNA secondary structure on RNP behavior

Michael SmalleganJohn RinnCU Boulder

The lncRNA Firre functions as a transcriptional activator

Wayne HemphillTom CechCU Boulder

Inter-polynucleotide transfer is intrinsic to PCR2 and supports an RNA-chromatin hand-off model

May 17, 2022Neelanjan MukherjeeNeelanjan MukherjeeCU Anschutz

Translational research: Treating Multiple Myeloma with Omacetaxine

Giulia CorbetRoy ParkerCU Boulder

dsRNA-induced condensation modulates PKR activation

Luis AguileraBrian MunskyColorado State University

Using single-molecule fluorescence microscopy and computational modeling to understand gene expression

DatePresentersLabInstitutionTitle
September 15, 2020Tim-Michael DeckerDylan TaatjesCU BoulderTargeted degradation of transcription elongation factor SPT5 using the dTAG system
Kelsey NassarAik-Choon TanCU AnschutzTranscriptomic analysis of mutant SF3B1 and its effects on mucosal melanoma oncogenesis
O'Neil WigganNeil WigganColorado State UniversityReal-time imaging of transcription and translation from an endogenous gene
October 20, 2020Frank LeeScott AlperNational Jewish HealthRegulating MyD88 alternative splicing in mouse macrophages
Megan CernyAmanda CharlesworthCU DenverDifferential expression of Oct paralogs during early development of Xenopus laevis
Conner LangebergJeffrey KieftCU AnschutzA conserved class of hystidylatable viral tRNA mimics
November 17, 2020Gongyi ZhangGongyi ZhangNational Jewish HealthRNA Polymerase II pausing regulation in higher eukaryotes
Traci LyonsTraci LyonsCU AnschutzInsights into pregnancy-related breast cancer through RNA analysis
Charlotte CialekTim StasevichCSUVisualizing dynamic tethering of Argonaute to single mRNA in live human cells
December 15, 2020Matthew TaylorMatthew TaylorCU AnschutzReading the tea leaves of the human cardiovascular transcriptome
Parker NicholsBeat VogeliCU AnschutzA-Z junction formation in Alu RNAs: A role for the Z-RNA binding domain of ADAR1
Robert BateyRobert BateyCU BoulderRiboswitches: Finding the hidden messages in the message
January 19, 2021Evan LesterRoy ParkerCU BoulderTau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components
Eugenia OlesnickyEugenia Olesnicky KillianUCCSTissue specific roles for the splicing factor Caper in aging and development
Rytis PrekerisRytis PrekerisCU AnschutzThe role of mid-body assocoated RNA in regulating cell proliferation and differentiation
February 16, 2021Ankita AroraMatthew TaliaferroCU AnschutzIdentifying RNA localization targets of TDP-43 using functional genomics
Sujatha JagannathanSujatha JagannathanCU AnschutzWhen cells' garbage disposal fails: Compromised RNA quality control in the human muscle disease FSHD
Jennyfer M MitchellJennyfer M MitchellCU Anschutzalx3 is a key player during early patterning of neurocranial elements in zebrafish
March 16, 2021Christian MuchJohn RinnCU BoulderSpatiotemporal dynamics of gene regulation by the lncRNA Firre
Olve PeersenOlve PeersenCSUCo-folding and membrane binding of poliovirus P3 polyprotein precursors
David BentleyDavid BentleyCU AnschutzTranscription speed: why it matters and how to control it
April 20, 2021Alicia CutlerBrad OlwinCU BoulderThere and back again a stem cell self-renewal tale
Raeann GoeringMatthew TaliaferroCU AnschutzMechanisms of RNA localization that transcend cell morphology
Richard DavisRichard DavisCU AnschutzArgonautes, small RNAs and programmed DNA elimination: A journey and saga
May 18, 2021Jeff MayfieldAmanda CharlesworthCU DenverTBD
Rachel JonesJeffrey KieftCU AnschutzRepeating history: New sequences and tertiary interactions create the same important 3-D features in divergent flavivrus xrRNAs
Hossein ShenasaDavid BentleyCU AnschutzMolecular insights into splice site selection
Date Presenters Lab Institution Title
September 17, 2019 Roman Iwasaki Robert Batey CU Boulder A Cas13-based assay rapidly quantifies transcription and enables biosensing of small molecules
Craig Forester Craig Forester CU Anschutz Dissecting specific translational activation in early hematopoiesis
Christopher Phiel Christopher Phiel CU Denver Stem cell pluripotency, metabolism, and m6A
Michael Cortázar Sujatha Jagannathan CU Anschutz Transcription elongation and termination: the sitting-duck torpedo model
October 15, 2019 Tom Santangelo   Colorado State University Abundant and diverse RNA modifications supporting thermophily in the Archaea
Rui Zhao Rui Zhao CU Anschutz Cryo-EM structure of spliceosomal E complex and biochemical analyses reveal a unified mechanism for intron definition, exon definition, and back-splicing
Yicheng Long Tom Cech CU Boulder RNA-protein interactions regulate epigenetic silencing
Stephanie Moon Roy Parker CU Boulder Coupling of translational quality control and mRNA targeting to stress granules
November 19, 2019 Esther Braselmann Esther Braselmann CU Boulder Illuminating RNA dynamics in mammalian cells with the Riboglow platform
Devin Tauber Roy Parker CU Boulder Modulation of RNA condensation by the DEAD-box protein eIF4A
Olivia Rissland Olivia Rissland CU Anschutz Connections between translation and mRNA decay
Allison Swain Aaron Johnson CU Anschutz m6A RNA modifications regulate lncRNA HOTAIR in breast cancer
December 10, 2019 John Rohloff Industry Somalogic Chemically-modified DNA aptamers
Brenna Dennison Katherine Fantauzzo CU Anschutz Srsf3-mediated alternative RNA splicing downstream of PDGFRα signaling in the palatal mesenchyme
Yuanyuan Xie Edward Chuong CU Boulder Harnessing transposon-derived dsRNA to kill cancer cells
Cecilia Levandowski Dylan Taatjes CU Boulder How does ∆40p53 alter p53 function?
January 21, 2020 Joseph Cardiello R Dowell & MA Allen CU Boulder Investigating the effects of Down syndrome on the induction of heat shock responsive gene mRNAs across a cellular population
Siddharth Shukla Roy Parker CU Boulder
Claire Gillette Tania Reis CU Anschutz RNA-binding proteins and fat storage homeostasis: a tale of fat flies
James Till Andres Vazquez-Torres CU Anschutz Linking nitrosative stress-induced metabolic adaptations to aminoglycoside tolerance
April 28, 2020 Danielle Bilodeau Olivia Rissland CU Anschutz Using long-read sequencing to validate RNA cleavage events in Giardia lamblia
Tom Evans Tom Evans CU Anschutz Genetic surprises: novel Sm family ncRNAs control developmental recovery from starvation in C. elegans
July 21, 2020 Otto Kletzien Robert Batey CU Boulder hnRNPU RGG is part of a larger RNA-binding domain
Kevin Hemphill Industry Horizon Discovery Chemical synthesis of long RNA for CRISPR mediated gene activation (CRISPRa)

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