Research

Overview

The Department of Pediatrics faculty conducts cutting-edge research across the entire breadth of pediatrics.

Our facilities, talented leadership, increased funding and new programs are working together to ensure the Department continues to make discoveries that will improve children’s health and will train the future pediatric investigators who will discover tomorrow’s treatments and cures.

    History: Research Discoveries and Milestones

    The Department of Pediatrics at the University of Colorado and Children's Hospital Colorado has a long and proud history of major research accomplishments which include the following pediatric research discoveries and milestones:

    • Performing the first pediatric liver transplant in the world (1963)
    • First description of the medical consequences of child abuse (The Battered Child Syndrome) (early 1960s)
    • Participation in clinical trials leading to the licensure of new pediatric vaccines, including Haemophilus influenza and meningococcus (1970s)
    • The description of toxic shock syndrome (TSS) (1978)
    • The first statewide newborn screening program for cystic fibrosis in the U.S. (1983)
    • Discovering the effects of Zinc and Vitamin E nutritional deficiencies in infants and children (1983)
    • Description of Kawasaki Syndrome (1976) in the U.S. and clinical trials, leading to its successful treatment with IVIG (1990s)
    • Groundbreaking research in the treatment of hemophilia and blood-clotting disorders (1980s and 1990s)
    • Methods to save newborns with severe lung disorders, including the treatment of pediatric pulmonary hypertension by using a non-invasive method of inhaled nitric oxide (1992)
    • Pioneering pediatric AIDS research, as one of a handful of AIDS clinical trial groups in U.S. (1993)
    • The Cystic Fibrosis Center participated in early research and drug trials for Kalydeco, the first drug that treats the underlying causes of CF (2006)
    • The development and licensure of a new shingles vaccine (2006)

    Strategic Plan

    As a part of our strategic plan for research the Department of Pediatrics in collaboration with Children’s Hospital Colorado hired a Chief Research Officer and Director of the Children’s Hospital Colorado Research Institute, Dr. Frederick J. Suchy, who has bridged research efforts between the various departments within the University of Colorado Anschutz Medical Campus and Children’s Colorado.

    Together we have developed new strengths in a number of focus areas through funding and aggressive recruiting.

    The involvement and financial commitment of both the Department of Pediatrics and Children’s Hospital Colorado towards the success of the Department’s strategic research plan has been, and will continue to be, key to our successes.

    Anschutz Medical Campus

    The Anschutz Medical Campus – which is the home to the University of Colorado Hospital, Children’s Hospital Colorado, and the University of Colorado School of Medicine – features state-of-the-art research laboratories and educational tools that encourage new collaborations and interdisciplinary research teams. These facilities create opportunities for the Department of Pediatrics to expand on its reputation as one of the top academic pediatric departments in the nation. 

    Research Institute

    The Children’s Hospital Colorado Research Institute is a leader in developing basic and clinical knowledge that drives our supply of new medicines, devices, diagnostic approaches and other health care innovations.

    As the umbrella organization for all research at Children’s Colorado, Children's Hospital Colorado Research Institute provides resources, oversight, funding, and expertise to new research programs at Children’s Colorado.

    Our research areas include:

    • Biology and Treatment of Childhood Cancer
    • Cardiopulmonary and Vascular Biology
    • Community Health and Disease Prevention
    • Developmental Origins of Health and Disease
    • Immunology Autoimmunity Inflammation and Infection
    • Genomics
    • Neuroscience

    Support for the Research Institute is aimed at funding promising physician scientists and pioneering their new ideas. To this end, the Research Institute is working collaboratively in:

    • conducting innovative basic laboratory investigation
    • performing patient-oriented research to translate discoveries at the laboratory bench into the improved clinical care for children
    • investigating the outcomes of treatments and methods of diagnosis to provide the best patient care
    • developing the next generation of clinical and basic pediatric investigators
    • engaging our community in studies to assure the health and well-being of all children.

    The Research Institute sponsors new research initiatives in all disciplines found at Children’s Colorado (including nursing and pathology). To learn more, visit the Children's Hospital Colorado Research Institute website.

    Colorado Clinical and Translational Sciences Institute

    The Colorado Clinical Translational Sciences Institute (CCTSI) brings together health organizations across Colorado with a goal to accelerate the translation of research discoveries into improved patient care and public health.

    The mission of the CCTSI is to transform the current clinical and translational research and training efforts of all schools at the University of Colorado and affiliated institutions into an innovative, interdisciplinary, integrated, collaborative campus and hospital-wide academic home for clinical and translational sciences, scientists and trainees.

    The CCTSI was established in 2008 with a $76 million Clinical and Translational Science Award (CTSA) from the NIH. 

    The CCTSI encourages and facilitates research and provides support through six major programs:

    • Discovery Translation
    • Community Translation
    • Education, Training and Career Development
    • Translational Informatics
    • Novel Methods and Technologies
    • Child and Maternal Health Research

    As part of the CTSA grant, the former Adult General Clinical Research Center (GCRC) at University of Colorado Hospital and the Children's Hospital Colorado CTRC – which were already being supported by the NIH – are now part of the Institute and have been transformed into a new network of Clinical Translational Research Centers (CTRCs).  

    To learn more, visit the Colorado Clinical Translational Sciences Institute website.

    Grants and Grants Management

    With our Grants Program Director and Associate Grants Program Director, and five grant specialists positions, we have created an infrastructure that supports our growing research portfolio, as well as addresses the complex issues that are involved with effective grants management. 

    Grants Program Director Jeanette Leeser is responsible for the overall program management and focus on strategic research needs for the future, as well as, the advancement of collaborative efforts. 

    Associate Grants Program Director Peggy Roddy​ is responsible for the day-today oversight and management of the team of grant specialists. 

    The five grant specialists are assigned to work with specific sections/principle investigators within the Department of Pediatrics.

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