Study to Explore Early Development (SEED) Follow Up Studies

PI (Component A): Carolyn DiGuiseppi, MD, PhD
PI (Component B): Cordelia Robinson Rosenberg, PhD, RN

Other participating personnel: Brian Be, Tessa Crume, Sandra Friedman, Kristina Hightshoe. Nuri Reyes, Ann Reynolds, Steve Rosenberg, Jessica Sanders, Sarah Schmiege, and Christine Cook

Component A – Enhanced Epidemiologic Research and Participant Follow-Up Surveys: The study will continue the work of previous SEED studies. Families enrolled in SEED Phases 1-3 will be contacted to answer questions about genetic, prenatal, early-life and family factors that contribute to autism spectrum disorder (ASD). The study will also look at differences and similarities in the behaviors, abilities, and health of young children with ASD. It will also provide insights into the experiences of adolescents with ASD as they mature through adolescence and into adulthood. The grant for Component A will run from July 2021 – June 2026.

Component B – In-Person Assessment of Intellectual Abilities of SEED Participants: The purpose of this study is to gain knowledge about the functioning of individuals with ASD through follow-up assessments of SEED 1-3 participants. This study will evaluate the reliability of childhood measures of intellectual status by comparing SEED participants’ current functioning (aged 8 to 22) with their abilities when they were preschoolers. These data will be used to examine factors that affect the stability of intellectual status, and its ability to predict transition outcomes. The grant for Component B will run from July 2021 – June 2025. 

Grant Funder: Centers for Disease Control and Prevention.

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