CYP2C9
When you take a medicine (or drug), your body needs to find a way to use it. Some proteins in your body break down (or metabolize) medicines. Breaking down a medicine can make it more active or less active, based on what kind of medicine you are taking. If your body breaks down a medicine too quickly or too slowly, this may make the medicine not work as well. It may also cause a side effect.
The CYP2C9 (say "SIP-2-SEE-9") gene helps your body make a protein that breaks down certain medicines, including:
| Medicine | Used For |
NSAIDs: Celecoxib, Ibuprofen, Meloxicam, Piroxicam | Pain Relief |
| Phenytoin & Fosphenytoin | Seizures |
| Siponimod | Multiple Sclerosis |
| Warfarin | Blood Clots |
These are the medicines that we know of right now that are impacted by CYP2C9 gene test results. Medical experts keep finding new data about which medicines are affected by gene test results.
By testing your DNA, we can find DNA differences. This can help us to see how well the proteins in your body work to break down certain medicines.
The results of your CYP2C9 gene test put you into 1 of 3 groups:
- Normal metabolizer: Your CYP2C9 proteins likely work normally.
- Intermediate metabolizer: Your CYP2C9 proteins may not work as well as they should.
- Poor metabolizer: Your CYP2C9 proteins may or may not work well at all.
The results of this test can help your doctor choose the right medicine and dose for you.