Patient Education Resources
Clinicians using the UCHealth EHR can use dotphrase: .pgxirinotecantopatientIrinotecan Tip Sheet
The following information is intended for use by providers who are attempting to prescribe irinotecan to patients with certain UGT1A1 genetic variants.
For immediate questions, send a secure chat message to Groups: "Pharmacogenomics Service" in UCHealth's EHR.
References:
- Hulshof EC et al. Dutch pharmacogenetics working group (DPWG) guideline for the gene-drug interaction between UGT1A1 and irinotecan, Eur J Hum Genet. 2022 Nov 28 online ahead of print. PMID: 36443464.
- Irinotecan Onivyde prescribing information. https://www.ipsen.com/websites/Ipsen_Online/wp-content/uploads/sites/9/2019/01/21083350/ONIVYDE_USPI.pdf
Irinotecan and UGT1A1 Tip Sheet by Christina L. Aquilante is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Webpage updated as of: 8/6/24