Clinical Intervention Translation Core

About the CIT Core

The CIT Core assists our research base with a wide range of clinical and translational research capacities including:

  • The modification of body weight
  • Diet and exercise interventions
  • The evaluation of a range of physiological and behavioral outcomes

This core provides a clinical infrastructure and expertise for studies of weight loss, weight loss maintenance and behavioral interventions, which makes substantial contributions to the scientific underpinnings to the national agenda to address the problem of obesity.

The CIT Core partners with the Anschutz Health and Wellness Center (AHWC) to utilize their state of the art facilities including a human performance lab, metabolic research kitchen, fitness center, wellness clinic, and numerous educational and community outreach programs.

The Colorado Clinical Translational Sciences Institute (CCTSI) Nutrition Core is also an important collaborator to the CIT Core, providing Registered Dietitian (RD) and nutritionist expertise among many other services. Additionally, the CIT Core provides the isotope ratio mass spectrometer (IRMS) assays of doubly labeled water (DLW) for the measurement of energy expenditure in the free-living environment. 

All services are provided on a fee for service basis.


Expertise in Health Behavior Change

  • Can assist in the design of clinical studies involving behavioral interventions and strategies to increase adherence to behavioral interventions. Initial consultation/meeting is free, ongoing support with collaboration and funding

Contact Kevin Masters to make an appointment for further information.






Weight Loss and Weight Loss Maintenance Services

  • Planning, resources, staff, and facilities for weight loss and weight loss maintenance interventions, including comprehensive behavioral support programs delivered by trained interventionalists
  • Behavioral weight loss interventions can be delivered one-on-one or in group/cohort-based settings, with options for in person or virtual delivery
  • Behavioral weight loss programs can be customized in regard to frequency of behavioral support and use of calorie-controlled diets and/or meal replacements to achieve weight loss targets of 5-15% over 8-26 weeks
  • Specialized weight loss curriculum can be developed by registered dietitians to meet study needs
  • Ongoing behavioral support for weight loss maintenance can also be provided


Services Provided in Conjunction with the CCTSI Nutrition Core

  • Metabolic meal planning and design, individualized for participant energy needs, food preferences, and study macro- and/or micro-nutrient targets
  • Metabolic meal preparation measurement, and dispensation
  • Ad libitum feeding
  • Design of specialty foods for targeted dietary interventions
  • Dietary intake assessment – habitual and during protocol interventions
  • Dietary intake can be assessed using traditional self-report tools, photographic food records, or novel passive capture devices
  • Hunger and satiety assessment
  • Assistance with measuring eating-related behaviors and appetite using validated tools and questionnaires

Visit the CCTSI website for more information on the CCTSI Nutrition Services.


Services Provided in Conjunction with AHWC

  • Clinic and meeting rooms for delivery of study interventions and performance of outcome measures
  • Phlebotomy
  • Indirect Calorimetry
  • EKG






statistical support

Statistical Support

  • Can provide statistical support for obesity, nutrition, and metabolism related studies, including initial consultation and power calculations for grant application (with developed specific aims) at no cost for NORC junior investigators
  • Fee for service for other investigators

Contact Zhaoxing Pan to make an appointment for further information.

CIT Core Contacts

DirectorJanine Higgins, PhD

Associate DirectorVicki Catenacci, PhD

View the CIT Team

Colorado Nutrition Obesity Research Center (NORC)

CU Anschutz Health and Wellness Center

12348 East Montview Boulevard

Aurora, CO 80045

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