I have more than 20 years of experience in the analysis of lipids by mass spectrometry as well as an in-depth knowledge of lipid biochemistry. My interest in lipid mass spectrometry began as a postdoctoral fellow in Robert Murphy’s laboratory at National Jewish Health where I was interested in the in vivo metabolism of a potent lipid mediator, leukotriene B4, in humans. My involvement in lipid mass spectrometry continued after my postdoc as a Senior Research Associate in Robert Murphy’s lab and as an instructor in the lipidomics core facility at the University of Colorado Anschutz Medical Campus where I gained valuable experience in the identification and quantitation of lipid molecular species and in the development LC-MS/MS and LC-MS/MS/MS methods to quantify a variety of lipid products. During this time, my research interests shifted into the development of novel mass spectrometric based methodologies (ion mobility and MALDI imaging) to elucidate lipid-based mechanisms of asthma, COPD, cardiovascular disease, age-related macular degeneration, and diabetic retinopathy. Currently, my major research interest is utilizing mass spectrometry as a tool to elucidate the role of lysophospholipids and oxidized phospholipids in insulin resistance. For this proposal, I will serve as the Associate Director of Molecular and Cellular Analytical (MCA) core for the Colorado Nutrition and Obesity Research Center (NORC), overseeing the NORC’s lipidomics facilities at the University of Colorado Anschutz Medical Campus. I am well qualified and well-positioned to help NORC advance the science of nutrition and obesity with quantitative lipidomics.