The Colorado NORC is managed by an Executive Committee comprised of the NORC Director, Associate Director, Core Directors, and Regular Members. An External Advisory Board advises our committee on major policy decisions and annually reviews the Colorado NORC's progress.
Email Address:darleen.sandoval@cuanschutz.edu
My research focuses on the role of the gut-brain axis in regulation of glucose and lipid metabolism and follows along two general themes. The first focuses on the role of a gastrointestinal peptide, GLP-1, in regulation of energy and glucose homeostasis. GLP-1 is made in the gut, the pancreas, and the brain and my work seeks to understand the role of the various sources of this peptide in normal glucose regulation, how dysregulation of GLP-1 is involved with the onset of type 2 diabetes mellitus, and how increases in GLP-1 seen with bariatric surgery contribute to diabetes resolution. The second focuses on the adaptations of the gut-brain axis with bariatric surgery and how this contributes to the profound weight-loss and improvements in glucose and lipid homeostasis seen with these surgeries. I have served on numerous committees including the ADA scientific sessions organizing committee, NIH Study Section (IPOD and currently NIDDK-C), and the Endocrine Society Annual Meeting Steering Committee. I am also proud to have co-founded the Women’s Interprofessional Network of the American Diabetes Association with Dr. Jane Reusch, for which I am also currently co-chair.