Christina Coughlan, PhD - Research Instructor

Headshot of Christina Coughlan

Contact Information

Email: Christina.Coughlan@cuanschutz.edu

Education

Postdoctoral Fellowship, University of Pennsylvania

PhD, University College Dublin

Biography

Christina Coughlan is a Senior Faculty Research Instructor in the lab of Dr. Potter in the Department of Neurology at the University of Colorado Anschutz Medical Center. Dr. Coughlan’s research interests are focused on finding biomarkers for Alzheimer’s disease (AD) and screening drugs for their ability to inhibit the development and progression of AD. Dr. Coughlan received her BSc (Hons) in Pharmacology and Toxicology and her PhD in Pharmacology from University College Dublin, Ireland. As a postdoctoral fellow at Ninewells Hospital and Medical school in Scotland, Dr. Coughlan received an Alzheimer’s Disease Society of Great Britain fellowship, an award only granted to ten in the UK at that time. Previous to joining CU Anschutz and the CU Alzheimer's and Cognition Center, Dr. Coughlan did a postdoctoral fellowship at the University of Pennsylvania and was an Assistant Professor of Biology at the University of Denver.

Recent Publications

Potter H, Woodcock JH, Boyd TD, Coughlan CM, O'Shaughnessy JR, Borges MT, Thaker AA, Raj AB, Adamszuk K, Scott D, Adame V, Anton P, Chial HJ, Gray H, Daniels J, Stocker ME, Sillau SH. Safety and efficacy of sargramostim (GM-CSF) in the treatment of Alzheimer's disease. Alzheimer's Dement. 2021;7:312158. https://doi.org/10.1002/trc2.12158

Coughlan CM, Bruce KD, Burgy O, Boyd TD, Michel CR, Garcia-Perez JE, Adame V, Anton P, Bettcher BM, Chial HJ, Koenigshoff M, Hsieh EWY, Graner M, Potter H. Exosome Isolation by Ultracentrifugation and Precipitation and Techniques for Downstream Analyses. Curr Protoc Cell Biol. 2020 Sep; 88(1):e110. PMID: 32633898.

Bubak AN, Como CN, Coughlan CM, Johnson NR, Hassell JE, Mescher T, Niemeyer CS, Mahalingam R, Cohrs RJ, Boyd TD, Potter H, Russ HA, Nagel MA. Varicella-Zoster Virus Infection of Primary Human Spinal Astrocytes Produces Intracellular Amylin, Amyloid-ß, and an Amyloidogenic Extracellular Environment. J Infect Dis. 2020 Mar 16; 221(7):1088-1097. PMID: 31665341.

A list of Dr. Coughlan's publications can be found on Colorado PROFILES