Unraveling the genetic and physiological pathways of human adaptation to hypoxia to improve maternal and infant health at high altitude and beyond.
Meet Our Team
Colleen G. Julian, PhD
Associate Professor, Department of Biomedical Informatics
Colleen G. Julian, PhD, received her doctoral degree from the University of Colorado Health Sciences Center.
She is now an associate professor at the University of Colorado School of Medicine. Her lab uses an integrative research approach that leverages natural high-altitude environments and population variability to identify therapeutic targets and predictive markers for pregnancy complications like preeclampsia and fetal growth restriction.
Kori Baker
MD Candidate
Baker is a MD candidate, researching impaired maternal cardiovascular performance as a predictor of altitude-associated fetal growth restriction.
Julie A. Houck
Research Services Principal Professional, Lab Manager
Houck is focused on empowering individuals with type 2 diabetes and peripheral vascular disease.
Hussna Yasini
MD Candidate
Yasini is studying the role of erythrocyte metabolome in altitude-associated fetal growth restriction.
Our Publications
Vascular Disorders of Pregnancy Increase Susceptibility to Neonatal Pulmonary Hypertension in High-Altitude Populations
High altitude regulates the expression of AMPK pathways in human placenta
Time Domains of Hypoxia Responses and -Omics Insights
Why is human uterine atery blood flow during pregnancy so high?
An Aptitude for Altitude: Are Epigenomic Processes Involved?
Pharmacological activation of Peroxisome proliferator-activated receptor y (PPAR-y) protects against hypoxia-associated fetal growth restriction
Peroxisome proliferator-activated receptor gamma blunts endothelin-1-mediated contraction of the uterine artery in a murine model of high-altitude pregnancy
Gain-of-function EGLN1 prolyl hydroxylase in combination with EPAS1 polymorphism lowers hemoglobin concentration in Tibetan highlanders
Natural Selection on Genes Related to Cardiovasular Health in High-Altitude Adapted Andeans
Beneficial Role of Erythocyte Adenosine A2B Receptor-Mediated AMP-Activated Protein Kinase Activation in High-Altitude Hypoxia
