Samantha Holden, MD - Director, Memory Disorders Clinic

Headshot of Dr. Samantha Holden

Contact Information



Fellowship, University of Colorado Anschutz Medical Campus

Residency, Neurology, Rush University Medical Center

MD, Stony Brook University School of Medicine

Professional Titles

Medical Director, University of Colorado Neurobehavior and Memory Disorders Clinic

Associate Director, Behavioral Neurology & Neuropsychiatry Fellowship

Co-Director, University of Colorado Lewy Body Dementia Association Research Center of Excellence


Samantha Holden, MD, is an Assistant Professor in the Department of Neurology at the University of Colorado Anschutz Medical Center. She currently practices in the Memory Disorders Clinic at University of Colorado Hospital. Dr. Holden received her BS in Neural Science from New York University and her MD from Stony Brook University School of Medicine. She completed her medical internship and neurology residency at Rush University Medical Center in Chicago, IL. With training in both behavioral neurology and movement disorders, Dr. Holden’s research focuses on cognition, behavior and quality of life in parkinsonian conditions. Her current research projects include determining the best methods for predicting and diagnosing dementia in Parkinson’s disease, as well as investigating non-pharmacological treatments for bothersome behavioral symptoms in dementia, such as music therapy. She is interested in developing practical and personally meaningful interventions to improve quality of life for people living with neurodegenerative dementias.

Recent Publications

Holden SK, Bettcher BM, Pelak VS. Update on posterior cortical atrophy. Curr Opin Neurol. 2020 Feb; 33(1):68-73.

Holden SK, Sheffler J, Stewart R, Thompson S, Persson J, Finseth T, Sillau S, Kluger BM. Feasibility of Home-Based Neurologic Music Therapy for Behavioral and Psychological Symptoms of Dementia: A Pilot Study. J Music Ther. 2019 Aug 13; 56(3):265-286

A list of publications for Dr. Holden can be found on Colorado PROFILES.