Canvas access has been restored for our users, but the service reliability remains uncertain. Due to recent events, Canvas has had intermittent outages which are at the discretion of the vendor and may occur during a final exam. Faculty and staff may continue to use Canvas, but we strongly advise faculty and students to prepare a contingency plan for turning in assignments and final exams in the event Canvas access becomes unavailable again.
Instructure, the company that owns Canvas, has provided an FAQ about the incident, which may not answer all your questions. We will share more information if it becomes available.
Our lab explores two dynamic areas at the intersection of virology, cancer biology, and metabolism.
First, we investigate how DNA tumor viruses—such as human papillomaviruses (HPVs) and human polyomaviruses (HPyVs)—drive infectious disease and cancer, including skin and head and neck malignancies. One of our key discoveries revealed that high-risk HPVs produce circular RNAs (circRNAs), including a circular E7 RNA (circE7) with coding potential and oncogenic properties (PMID: 31127091). This breakthrough has opened new areas of investigation on the regulation and function of both viral and cellular.
Second, we study how glucose transport and metabolism shape tissue homeostasis and contribute to disease. Our work shows that facilitative glucose transporters, such as GLUT1 and GLUT3, do far more than move hexoses—they play unexpected roles in regulating tissue homeostasis and signal transduction. These insights have important implications for inflammatory and neoplastic skin disorders (PMID: 29662201, 37721853).