Lab Research
Our faculty strive to discover the molecular and cellular basis of diseases affecting the skin. This new knowledge is applied to the prevention, diagnosis, and treatment of these diseases. Research activities include investigating the molecular biology and immunology of the skin, dermato-epidemiology, genetic determinants of skin diseases including skin cancer, and development of gene therapy approaches. Read more about our faculty labs and their latest publications in the categories below.
The scope of skin disease related research at the University of Colorado is embodied in the University of Colorado Anschutz Medical Center Skin Diseases Research Center (UCAMC-SDRC). This NIAMS-funded center focuses on organizing and supporting research to better understand the molecular basis of human autoimmune, inflammatory, developmental, metabolic, and genetic skin diseases. The broad goal of this SDRC is to help member investigators develop models of human skin diseases as research platforms to study molecular mechanisms of disease. This provides us with the opportunity to develop innovative molecular approaches to correct disease processes and explore new treatment approaches.
This center includes a multitude of investigators, many from within the Department of Dermatology along with partnerships from other UCAMC Departments or outside collaborators. The research interests of these investigators are broad: inflammation and immunity; epithelial biology; melanocyte biology; regenerative medicine and stem cell biology; molecular, cellular, and developmental biology; biochemistry; pharmacology; microbiology and virology; genetics and genomics; tissue repair; cutaneous carcinogenesis; and clinical research. This is a rich platform for interdisciplinary discovery in basic and translational research.
This center is built on the strong foundation of three collaborative research teams within the Anschutz Medical Campus, all headed by scientists with an established record of NIAMS-funded research: The Department of Dermatology, the Center for Regenerative Medicine and Stem Cell Biology, and the Human Medical Genetics Program. There are also strong collaborations with other centers on the AMC, especially the NCI-funded University of Colorado Comprehensive Cancer Center.
Director of Research Core
Associate Director of Gates Institute
Director of Clinical Research
Vice Chair of Research
Director of Research Mentoring
https://shellmanlab.github.io/
The Gates Institute team is a collaborative group representing a variety of disciplines, dedicated to advancing research in stem cell biology and regenerative medicine to accelerate discoveries from concepts to cures. Dermatology professor Dennis Roop, Ph.D., is the associate director of Gates Institute at the University of Colorado Anschutz Medical Campus. Dermatology faculty members Dr. Anya Bilousova, Dr. Igor Kogut, Dr. Xiying Fan, and Dr. Yiqun Shellman are also Gates Institute Research Members.
On July 21, 2024, MOHS Fellowship director Dr. Fiona Zwald and new MOHS fellow, Dr. Lydia Luu joined other Coloradans for the 25th Annual Donor Dash. The 5k walk at Washington Park in Denver aimed to Honor, Celebrate and Recognize those touched by organ, eye and tissue donation. The day began at 8 am, followed by inspirational speakers and a ribbon ceremony. Ali Walker, the administrator for Fiona Zwald’s transplant dermatology clinic at CU Anschutz, also joined the race with her friendly dog. The Donor Dash is a wonderful opportunity to connect with the real-world impact of transplants, and the unique gratitude shared between recipients and donors’ families.
Learn more about the Donor Dash event. https://www.donoralliance.org/donor-dash/
From Donate Dash’s Facts and Statistics
Just one donor can save up to eight lives through organ donation and save or heal more than 75 lives through eye and tissue donation. Approximately 500,000 Americans are saved by organ and tissue donation each year.
In Colorado and Wyoming alone nearly 1,300 people are on the waiting list for a lifesaving organ transplant. Nearly 115,000 people are waiting nationwide. Every 10 minutes another name is added to the national transplant waiting list. Thousands more patients could benefit from lifesaving and healing eye and tissue donations.
Residents can register their decision to be organ, eye and tissue donors at the time of their deaths by saying Yes each time they obtain or renew a driver’s license or state ID, or at www.DonateLifeColorado.org or www.DonateLifeWyoming.org anytime.