$15,000,000
Awarded In Private & Federal Grants
We use partner engagement and pragmatic D&I models, methods and measures to build D&I capacity among scientists, healthcare settings and communities; develop, test and disseminate sustainable, generalizable and equitable solutions to real world health problems; and consult with and train those interested in applying D&I methods
$15,000,000
Awarded In Private & Federal Grants
10
D&I Scholars Trained Through Our Certificate Program
89
Publications In 2 Years By Our Team
Authorship: Jodi Holtrop, et. al.
Given the multitude of methods available, choosing appropriate and feasible methods can be challenging, leading many to rely on a limited set of methods. Navigational assistance with methods decision-making, including choosing to use less common methods, is lacking. This paper outlines how to select study method, beginning with the research goal and the type of research question(s), and presents methods options based on key characteristics of the research.
Trinkley K., et. al.
Objective: The purpose of this paper is to describe a systematic and pragmatic approach grounded in implementation science to identify and prioritize how best to incorporate different types of nudges into CDS tools. We provide a case example of how this systematic approach was applied to design a CDS tool to improve guideline-concordant prescribing of mineralocorticoid receptor antagonists for patients with heart failure and reduced ejection fraction.
Authorship: Borsika A. Rabin, et. al.
Conclusion: This review has provided an overview of the literature and a synthesis of best practices to systematically document and analyze adaptations across the phases of a program and common scenarios for the documentation adaptations.
Authorship: Mónica Pérez Jolles, et. al.
In this paper, we describe how Implementation Mapping was used to engage diverse stakeholders and guide them through a systematic process that resulted in the development of the implementation strategy. We also detail how the EPIS framework informed each Implementation Mapping Task and provide recommendations for developing implementation strategies using EPIS and Implementation Mapping in health-care settings.
Adsul P, Kanabar N, Kruse-Diehr A, Dignan M, Oliveri JM, Paskett ED, Reuland DS, Ferrari RM, Moore AA, Polite B, Kim K, Gupta S, Castañeda SF, Martinez ME, Hatcher J, Coury J, Kenzie ES, Petrik AF, Coronado GD, Liebovitz D, Blanchard J, Hoover S, English K, Mishra SI, Davis MM, Rabin BA. Generating the evidence base for implementation strategies targeting colorectal cancer screening in the accelerating colorectal cancer screening through implementation science (ACCSIS) research projects. BMC Public Health. 2026 Jan 24;26(1):576. doi: 10.1186/s12889-025-26179-2. PMID: 41580763; PMCID: PMC12896049.
Cervantes L, Rizzolo K, Tummalapalli SL, Wainstein M, Glasgow RE, Jolles MP. Use of a Context- and Equity-Focused Implementation Science Framework to Aid the Design of Clinical Trials. J Am Soc Nephrol. 2025 Jun 1;36(6):1197-1200. doi: 10.1681/ASN.0000000633. Epub 2025 Jan 17. PMID: 39823190; PMCID: PMC12147963.
Cervantes L, Tummalapalli SL, Tuot D, Glasgow RE. The role of implementation science in advancing equity in kidney health. Nat Rev Nephrol. 2025 Jun;21(6):357-359. doi: 10.1038/s41581-025-00949-y. PMID: 40069320
Aschbrenner KA, Rabin BA, Bartels SJ, Glasgow RE. Methodological recommendations for assessing the impact of adaptations on outcomes in implementation research. Implement Sci. 2025 Jun 23;20(1):30. doi: 10.1186/s13012-025-01441-8. PMID: 40551189; PMCID: PMC12183851.
Cervantes L, Rizzolo K, Ram A, Glasgow RE, Earnest M. Engaging in Advocacy to Promote Policy Change: Incorporating Advocacy-Informed Research and Applying the PRISM Implementation Science Model. J Gen Intern Med. 2026 Jan 23. doi: 10.1007/s11606-026-10169-0. Epub ahead of print. PMID: 41578106.
Demedis J, Reedy J, Miller K, Hu J, Klosky JL, Dorsey Holliman B, Peterson PN, Chow EJ, Studts C. Testing effectiveness and implementation of a standardized approach to sexual dysfunction screening among adolescent and young adult-aged survivors of childhood cancer: A type I hybrid, mixed methods trial protocol. PLoS One. 2024 Jul 22;19(7):e0305677. doi: 10.1371/journal.pone.0305677. PMID: 39038011; PMCID: PMC11262696.
Fox K, Passey D, Kang E, Zeigen L, Kenzie E, Austin JD, Meadows RJ, Fernandez ME, Perez Jolles M. Application of core functions and forms in complex health intervention research: a scoping review protocol. BMJ Open. 2025 Jan 8;15(1):e091088. doi: 10.1136/bmjopen-2024-091088. PMID: 39779266; PMCID: PMC11749525.
Glasgow RE, Trinkley KE, Ford B, Rabin BA. The Application and Evolution of the Practical, Robust Implementation and Sustainability Model (PRISM): History and Innovations. Glob Implement Res Appl. 2024;4(4):404-420. doi: 10.1007/s43477-024-00134-6. Epub 2024 Aug 31. PMID: 39568619; PMCID: PMC11573842.
Hirsch EA, Studts JL, Zane S, McCreight M, Huebschmann AG. Evaluating Pragmatism of Lung Cancer Screening Randomized Trials with the PRECIS-2 Tool. J Am Board Fam Med. 2025 May 12;38(1):56-83. doi: 10.3122/jabfm.2024.240142R1. PMID: 40300826; PMCID: PMC12096383.
Holtrop JS, Gurfinkel D, Nederveld A, Reedy J, Rubinson C, Kwan BM. What works in implementing shared medical appointments for patients with diabetes in primary care to enhance reach: a qualitative comparative analysis from the Invested in Diabetes study. Implement Sci Commun. 2024 Jul 24;5(1):82. doi: 10.1186/s43058-024-00608-6. PMID: 39049078; PMCID: PMC11267890.
Kwan BM, Sobczak C, Fish LE, Ginde AA, Grant G, Hamer MK, Leggott K, Owen V, Reno J, Shrader J, Whittington L, Jones JL, Koren R, Begay JA, Vinaithirthan V, Lum HD. Rapid methods for multi-level dissemination of neutralizing monoclonal antibody treatment for COVID-19 outpatients: designing for dissemination using the fit to context framework. Front Public Health. 2024 Nov 21;12:1412947. doi: 10.3389/fpubh.2024.1412947. PMID: 39639913; PMCID: PMC11617208.
Paniagua-Avila A, Shelton RC, Figueroa JC, Guzman AL, Gutierrez L, Hernandez-Galdamez DR, Ramirez JM, Rodriguez J, Irazola V, Ramirez-Zea M, Fort MP. Assessing the implementation of a multi-component hypertension program in a Guatemalan under-resourced dynamic context: an application of the RE-AIM/PRISM extension for sustainability and health equity. Implement Sci Commun. 2024 Mar 15;5(1):23. doi: 10.1186/s43058-024-00560-5. PMID: 38491376; PMCID: PMC10941412.
Pittman JOE, Lindamer L, Almklov E, Glasgow RE, Huebschmann AG, Trinkley KE, Huynh B, Rabin BA. Development of a pragmatic measure for the Practical, Robust Implementation and Sustainability Model. Psychol Serv. 2025 Apr 10. doi: 10.1037/ser0000947. Epub ahead of print. PMID: 40208716.
Perez Jolles M, Willging C, Tufte J, Ostendorf D, Kwan BM, Sevick C, Dorsey Holliman B, Weiner BJ. Development and validation of a pragmatic measure of cocreation in research engagement: a study protocol. BMJ Open. 2024 Dec 20;14(12):e091966. doi: 10.1136/bmjopen-2024-091966. PMID: 39806684; PMCID: PMC11667353.
Perez LG, Merle JL, Smith JD, Dopp AR, Huebschmann AG. IM4Equity: an implementation science meta-framework for community-engaged partnerships to advance health equity. BMC Health Serv Res. 2025 Mar 26;25(1):437. doi: 10.1186/s12913-025-12537-8. PMID: 40140849; PMCID: PMC11948705.
Salgin L, Reyes BJ, Bojorquez MB, Lomeli A, Velasquez S, Cain KL, Seifert M, Laurent LC, Stadnick NA, Rabin BA. Using multi-method approaches to document and assess adaptations in a community-driven COVID-19 testing program. Implement Sci Commun. 2026 Feb 5;7(1):47. doi: 10.1186/s43058-026-00871-9. PMID: 41639712; PMCID: PMC12977873.
Swanson K, Stadnick NA, Aarons GA, Brookman-Frazee L, Bouchard I, Du Z, Brubaker A, Geremia C, Cain K, Conradi L, Sklar M, Viglione C, Rabin B. Beyond the Surface of Capacity Building: A Mixed-Methods Study of the Core Functions and Forms of Dissemination and Implementation Science Consultations. Res Sq [Preprint]. 2025 May 13:rs.3.rs-6559185. doi: 10.21203/rs.3.rs-6559185/v1. PMID: 40470185; PMCID: PMC12136196.
Trinkley KE, Glasgow RE. From Automation to Action in Heart Failure: Digital Solutions, Pragmatic Evidence, and the Integrative Role of Implementation Science. Circ Heart Fail. 2026 Feb;19(2):e013900. doi: 10.1161/CIRCHEARTFAILURE.125.013900. Epub 2026 Jan 29. PMID: 41608797.
Trinkley KE, Gohil S, Salsbury SA, Burgess DJ, Doorenbos AZ, Mittman BS, Norton WE, Bosworth HB, Staman KL, Check D. Collection of implementation-related data in pragmatic clinical trials: a cross-sectional study from the NIH Pragmatic Trials Collaboratory. Implement Sci Commun. 2026 Feb 13;7(1):48. doi: 10.1186/s43058-026-00868-4. PMID: 41680937; PMCID: PMC13005506.