Research


Urology Research Program

The Urology Research Program, directed by Anna Malykhina, MD, PhD, conducts basic and translational research focused on the mechanisms underlying pathological changes in benign urological disorders in adults and children.


Publications

The list of publications below represents a sample of recent clinical research by faculty members across the Division of Urology. For a printer-friendly version, click the PDF below.

2019

The Expression of Transcription Factors Mecp2 and CREB Is Modulated in Inflammatory Pelvic Pain. Xie AX, Pan XQ, Meacham RB, Malykhina AP. Front Syst Neurosci. 2019 Jan 11;12:69. doi: 10.3389/fnsys.2018.00069. eCollection 2018. PMID: 30687029

Altered detrusor contractility and voiding patterns in mice lacking the mechanosensitive TREK-1 channel. Pineda RH, Hypolite J, Lee S, Carrasco A Jr, Iguchi N, Meacham RB, Malykhina AP. BMC Urol. 2019 May 21;19(1):40. doi: 10.1186/s12894-019-0475-3. PMID: 31113422

Focal laser ablation as clinical treatment of prostate cancer: report from a Delphi consensus project. van Luijtelaar A, Greenwood BM, Ahmed HU, Barqawi AB, Barret E, Bomers JGR, Brausi MA, Choyke PL, Cooperberg MR, Eggener S, Feller JF, Frauscher F, George AK, Hindley RG, Jenniskens SFM, Klotz L, Kovacs G, Lindner U, Loeb S, Margolis DJ, Marks LS, May S, Mcclure TD, Montironi R, Nour SG, Oto A, Polascik TJ, Rastinehad AR, De Reyke TM, Reijnen JS, de la Rosette JJMCH, Sedelaar JPM, Sperling DS, Walser EM, Ward JF, Villers A, Ghai S, Fütterer JJ. World J Urol. 2019 Oct;37(10):2147-2153. doi: 10.1007/s00345-019-02636-7. Epub 2019 Jan 22. PMID: 30671638

Robotic-assisted Laparoscopic Subtrigonal Inlay of Buccal Mucosal Graft for Treatment of Refractory Bladder Neck Contracture. Avallone MA, Quach A, Warncke J, Nikolavsky D, Flynn BJ. Urology. 2019 Aug;130:209. doi: 10.1016/j.urology.2019.02.048. Epub 2019 May 4. PMID: 31063762

A national survey of radiation oncologists and urologists on prediction tools and nomograms for localized prostate cancer. Gershman B, Maroni P, Tilburt JC, Volk RJ, Konety B, Bennett CL, Kutikov A, Smaldone MC, Chen V, Kim SP. World J Urol. 2019 Oct;37(10):2099-2108. doi: 10.1007/s00345-019-02637-6. Epub 2019 Jan 22. PMID: 30671637

Partial Versus Radical Nephrectomy for the Clinical T1a Renal Mass. Gershman B, Leibovich BC, Kim SP. Eur Urol Focus. 2019 Nov;5(6):970-972. doi: 10.1016/j.euf.2019.02.005. Epub 2019 Feb 15. PMID: 30777722

Contemporary Trends in Magnetic Resonance Imaging at the Time of Prostate Biopsy: Results from a Large Private Insurance Database. Kim SP, Karnes RJ, Mwangi R, Van Houten H, Gross CP, Gershman B, Leapman MS, Shah ND. Eur Urol Focus. 2019 Apr 29. pii: S2405-4569(19)30102-6. doi: 10.1016/j.euf.2019.03.016. [Epub ahead of print] PMID: 31047904

Outcomes of upper tract urothelial carcinoma with isolated lymph node involvement following surgical resection: implications for multi-modal management. Pelcovits A, Mueller-Leonhard C, Mega A, Amin A, Kim SP, Golijanin D, Gershman B. World J Urol. 2019 Aug 6. doi: 10.1007/s00345-019-02897-2. [Epub ahead of print] PMID: 31388818

Clinically node-positive (cN+) urothelial carcinoma of the bladder treated with chemotherapy and radical cystectomy: Clinical outcomes and development of a postoperative risk stratification model. Al-Alao O, Mueller-Leonhard C, Kim SP, Amin A, Tucci C, Kott O, Mega A, Golijanin D, Gershman B. Urol Oncol. 2019 Oct 5. pii: S1078-1439(19)30354-0. doi: 10.1016/j.urolonc.2019.09.003. [Epub ahead of print] PMID: 31590968

Editorial Comment. Pessoa RR, Kukreja J. J Urol. 2019 Dec;202(6):1253. doi: 10.1097/01.JU.0000581808.25475.cf. Epub 2019 Jul 30. No abstract available. PMID: 31469612

Association of Hospital Altitude and Postoperative Infectious Complications After Major Operations. Aasen DM, Wiedel C, Maroni P, Cohen ME, Meng X, Meguid RA. High Alt Med Biol. 2019 Oct 16. doi: 10.1089/ham.2019.0062. [Epub ahead of print] PMID: 31618098

Differential effect of grape seed extract and its active constituent procyanidin B2 3,3″-di-O-gallate against prostate cancer stem cells. Tyagi A, Kumar S, Raina K, Wempe MF, Maroni PD, Agarwal R, Agarwal C. Mol Carcinog. 2019 Jul;58(7):1105-1117. doi: 10.1002/mc.22995. Epub 2019 Mar 3. PMID: 30828884

A Clinician's Guide to Next Generation Imaging in Patients With Advanced Prostate Cancer (RADAR III). Crawford ED, Koo PJ, Shore N, Slovin SF, Concepcion RS, Freedland SJ, Gomella LG, Karsh L, Keane TE, Maroni P, Penson D, Petrylak DP, Ross A, Mouraviev V, Reiter RE, Divgi C, Yu EY; RADAR III Group. J Urol. 2019 Apr;201(4):682-692. doi: 10.1016/j.juro.2018.05.164. Review. PMID: 30077557

A decision tree to guide long term venous access placement in children and adolescents undergoing surgery for renal tumors. Saltzman AF, Carrasco A Jr, Hecht S, Walker J, Caldwell BT, Bruny JL, Cost NG. J Pediatr Surg. 2019 May 11. pii: S0022-3468(19)30343-4. doi: 10.1016/j.jpedsurg.2019.04.034. [Epub ahead of print] PMID: 31128844

Appropriateness for testis-sparing surgery based on the testicular tumor size in a pediatric and adolescent population.

Caldwell BT, Saltzman AF, Maccini MA, Cost NG. J Pediatr Urol. 2019 Feb;15(1):70.e1-70.e6. doi: 10.1016/j.jpurol.2018.10.011. Epub 2018 Oct 23. PMID: 30448079

A Contemporary Analysis of Pediatric Urology Surgical Volume at a Tertiary Care Center. Goodstein TA, Cost NG, Campbell JB, Vemulakonda V, Wilcox D, Saltzman AF. Urology. 2019 Mar;125:179-183. doi: 10.1016/j.urology.2018.12.030. Epub 2019 Jan 2. PMID: 30610906

Embracing change-the time for pediatric enhanced recovery after surgery is now. Rove KO, Brockel MA, Brindle ME, Scott MJ, Herndon CDA, Ljungqvist O, Koyle MA; Pediatric ERAS® (Enhanced Recovery Ater Surgery) Society. J Pediatr Urol. 2019 Apr 23. pii: S1477-5131(19)30080-4. doi: 10.1016/j.jpurol.2019.04.005. [Epub ahead of print] No abstract available. PMID: 31109886

Genetic Testing Proves Crucial in Case of Ambiguous Genitalia and Renal Masses. Weaver J, Rove KO, Meenakshi-Sundaram B, Vricella GJ. Urology. 2019 Jul;129:194-196. doi: 10.1016/j.urology.2019.03.011. Epub 2019 Mar 23. PMID: 30914336

Clinically node-positive (cN+) urothelial carcinoma of the bladder treated with chemotherapy and radical cystectomy: Clinical outcomes and development of a postoperative risk stratification model. Al-Alao O, Mueller-Leonhard C, Kim SP, Amin A, Tucci C, Kott O, Mega A, Golijanin D, Gershman B. Urol Oncol. 2019 Oct 5. pii: S1078-1439(19)30354-0. doi: 10.1016/j.urolonc.2019.09.003. [Epub ahead of print] PMID: 31590968

A Clinician's Guide to Next Generation Imaging in Patients With Advanced Prostate Cancer (RADAR III). Crawford ED, Koo PJ, Shore N, Slovin SF, Concepcion RS, Freedland SJ, Gomella LG, Karsh L, Keane TE, Maroni P, Penson D, Petrylak DP, Ross A, Mouraviev V, Reiter RE, Divgi C, Yu EY; RADAR III Group. J Urol. 2019 Apr;201(4):682-692. doi: 10.1016/j.juro.2018.05.164. Review. PMID: 30077557

Dermatofibrosarcoma Protuberans in a Male Infant. Peard L, Cost NG, Saltzman AF. Urology. 2019 Jul;129:206-209. doi: 10.1016/j.urology.2018.08.050. Epub 2018 Nov 10. PMID: 30423303

Technical Considerations for Nephron-Sparing Surgery in Children: What Is Needed to Preserve Renal Units? Aldrink JH, Cost NG, McLeod DJ, Bates DG, Stanek JR, Smith EA, Ehrlich PF. J Surg Res. 2018 Dec;232:614-620. doi: 10.1016/j.jss.2018.07.022. Epub 2018 Aug 9. PMID: 30463781

Adult Wilms Tumor During Pregnancy: Case Report and Literature Review. Walker JP, Saltzman AF, Kessler ER, Cost NG. Urology. 2019 Jul;129:200-205. doi: 10.1016/j.urology.2018.11.045. Epub 2018 Dec 28. PMID: 30597169

The Natural History of Wilms Tumor-A Case Comparison of Two Different Tumors. Walker JP, Meyers ML, Saltzman AF, Hecht SL, Cost NG. Urology. 2019 Aug;130:151-154. doi: 10.1016/j.urology.2019.02.015. Epub 2019 Feb 23. PMID: 30807774

Factors related to lymph node sampling at the time of surgery in children, adolescents, and young adults with unilateral non-metastatic renal cell carcinoma. Saltzman AF, Stokes W, Walker J, Cost NG. J Pediatr Urol. 2019 May;15(3):259.e1-259.e7. doi: 10.1016/j.jpurol.2019.01.009. Epub 2019 Feb 1. PMID: 30819622

Doxorubicin induces detrusor smooth muscle impairments through myosin dysregulation, leading to a risk of lower urinary tract dysfunction. Iguchi N, Dönmez Mİ, Carrasco A Jr, Wilcox DT, Pineda RH, Malykhina AP, Cost NG. Am J Physiol Renal Physiol. 2019 Jul 1;317(1):F197-F206. doi: 10.1152/ajprenal.00090.2019. Epub 2019 May 8. PMID: 31066574

Expert opinion: open primary, nerve-sparing retroperitoneal lymph node dissection. Cost NG. J Pediatr Urol. 2019 May;15(3):273. doi: 10.1016/j.jpurol.2019.06.003. No abstract available. PMID: 31221397

Pediatric pheochromocytoma: current status of diagnostic imaging and treatment procedures. Peard L, Cost NG, Saltzman AF. Curr Opin Urol. 2019 Sep;29(5):493-499. doi: 10.1097/MOU.0000000000000650. PMID: 31246590

How Many Lymph Nodes Are Enough? Assessing the Adequacy of Lymph Node Yield for Staging in Favorable Histology Wilms Tumor. Saltzman AF, Smith DE, Gao D, Ghosh D, Amini A, Aldrink JH, Dasgupta R, Gow KW, Glick RD, Ehrlich PF, Cost NG. J Pediatr Surg. 2019 Jun 20. pii: S0022-3468(19)30407-5. doi: 10.1016/j.jpedsurg.2019.06.010. [Epub ahead of print] PMID: 31255328

Partial Nephrectomy for Multifocal, Unilateral Wilms Tumor in a Patient with Hemihypertrophy. Romero NG, Walker J, Cost NG, Saltzman AF. Urology. 2019 Nov;133:243-244. doi: 10.1016/j.urology.2019.07.031. Epub 2019 Aug 9. PMID: 31404584

Open Radical Nephrectomy for Suspected Renal Malignancy-Tips and Tricks. Loomis J, Peard L, Walker J, Cost NG, Saltzman AF. Urology. 2019 Nov;133:241-242. doi: 10.1016/j.urology.2019.08.002. Epub 2019 Aug 13. PMID: 31419431

Patterns of Care and Survival Comparison of Adult and Pediatric Wilms Tumor in the United States: A Study of the National Cancer Database. Saltzman AF, Carrasco A Jr, Amini A, Cost NG. Urology. 2019 Oct 25. pii: S0090-4295(19)30923-9. doi: 10.1016/j.urology.2019.10.007. [Epub ahead of print] PMID: 31669270

Isolated pure malignant rhabdoid tumor (MRT) of the bladder: case report and lessons learned. Hecht SL, Walker JP, Treece AL, Cost NG. Urology. 2019 Nov 13. pii: S0090-4295(19)30974-4. doi: 10.1016/j.urology.2019.10.023. [Epub ahead of print] PMID: 31733273

Surgical decision-making in infants with suspected UPJ obstruction: stakeholder perspectives. Vemulakonda VM, Hamer MK, Kempe A, Morris MA. J Pediatr Urol. 2019 May 30. pii: S1477-5131(19)30147-0. doi: 10.1016/j.jpurol.2019.05.027. [Epub ahead of print] PMID: 31239100

Providing Access: Differences in Pediatric Portal Activation Begin at Patient Check-in. Bush RA, Vemulakonda VM, Richardson AC, Deakyne Davies SJ, Chiang GJ. Appl Clin Inform. 2019 Aug;10(4):670-678. doi: 10.1055/s-0039-1695792. Epub 2019 Sep 11. PMID: 31509879

Ectopic ureters in anorectal malformations. Hecht S, Hall J, Ketzer J, Walker J, Trecartin A, Wilcox D, Peña A, Bischoff A. Pediatr Surg Int. 2019 Sep;35(9):1005-1008. doi: 10.1007/s00383-019-04517-x. Epub 2019 Jul 5. PMID: 31278478

A Study of Adolescent Female Genitalia: What is Normal? Brodie K, Alaniz V, Buyers E, Caldwell B, Grantham E, Sheeder J, Wilcox D, Huguelet P. J Pediatr Adolesc Gynecol. 2019 Feb;32(1):27-31. doi: 10.1016/j.jpag.2018.09.007. Epub 2018 Sep 20. PMID: 30244193

Transition of care: a growing concern in adult patients born with colorectal anomalies. Acker S, Peña A, Wilcox D, Alaniz V, Bischoff A. Pediatr Surg Int. 2019 Feb;35(2):233-237. doi: 10.1007/s00383-018-4401-7. Epub 2018 Nov 3. PMID: 30392127

Inpatient interventions that may preclude outpatient open pyeloplasty in infants. Dönmez Mİ, Carrasco A Jr, Saltzman AF, Wilcox DT. Int Braz J Urol. 2019 Jan-Feb;45(1):145-149. doi: 10.1590/S1677-5538.IBJU.2018.0252. PMID: 30620155

Distribution of a photographic atlas did not reduce postoperative care utilization after pediatric circumcision or the indispensability of the pediatric urology clinic nurse. Danzig MR, Wild TT, Holbrook S, Wilcox DT. J Pediatr Urol. 2019 May;15(3):227.e1-227.e6. doi: 10.1016/j.jpurol.2019.02.016. Epub 2019 Mar 7. PMID: 30940432

Error traps and culture of safety in anorectal malformations. Bischoff A, Bealer J, Wilcox DT, Peña A. Semin Pediatr Surg. 2019 Jun;28(3):131-134. doi: 10.1053/j.sempedsurg.2019.04.016. Epub 2019 Apr 25. PMID: 31171146

A cloacal anomaly is not a disorder of sex development. Bischoff A, Trecartin A, Alaniz V, Hecht S, Wilcox DT, Peña A. Pediatr Surg Int. 2019 Sep;35(9):985-987. doi: 10.1007/s00383-019-04511-3. Epub 2019 Jun 29. PMID: 31256297

Editorial Comment. Kim FJ, da Silva RD. Urology. 2015 Nov;86(5):945. doi: 10.1016/j.urology.2015.05.048. Epub 2015 Sep 3. No abstract available. PMID: 26343238

Social Media in the Urology Practice | Opinion: NO. Da Silva RD, Leow JJ, Abidin ZA, Linden-Castro E, Castro EIB, Blanco LT, Teoh JY, Contreras PN, Wroclawski ML. Int Braz J Urol. 2019 Sep-Oct;45(5):882-888. doi: 10.1590/S1677-5538.IBJU.2019.05.04. No abstract available. PMID: 31626517

BCG Renal Granuloma. Marks J, Argyres M, Lloyd G. Urology. 2019 May;127:e10. doi: 10.1016/j.urology.2019.01.026. Epub 2019 Feb 8. PMID: 30738884

Benign Prostatic Hyperplasia and Lower Urinary Tract Symptoms: What Is the Role and Significance of Inflammation? Lloyd GL, Marks JM, Ricke WA. Curr Urol Rep. 2019 Aug 3;20(9):54. doi: 10.1007/s11934-019-0917-1. Review. PMID: 31377881

Is Your Career Hurting You? The Ergonomic Consequences of Surgery in 701 Urologists Worldwide. Lloyd GL, Chung ASJ, Steinberg S, Sawyer M, Williams DH, Overbey D. J Endourol. 2019 Jul 17. doi: 10.1089/end.2019.0150. [Epub ahead of print] PMID: 31187638

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing. Liu TT, Rodgers AC, Nicholson TM, Macoska JA, Marker PC, Vezina CM, Bjorling DE, Roldan-Alzate A, Hernando D, Lloyd GL, Hacker TA, Ricke WA. J Vis Exp. 2019 Aug 14;(150). doi: 10.3791/59802. PMID: 31475976

Illness uncertainty, partner support, and quality of life: A dyadic longitudinal investigation of couples facing prostate cancer. Varner S, Lloyd G, Ranby KW, Callan S, Robertson C, Lipkus IM. Psychooncology. 2019 Nov;28(11):2188-2194. doi: 10.1002/pon.5205. Epub 2019 Sep 2. PMID: 31418505

2018

A Clinician's Guide to Next Generation Imaging in Patients With Advanced Prostate Cancer (Prostate Cancer Radiographic Assessments for Detection of Advanced Recurrence [RADAR] III). Crawford ED, Koo PJ, Shore N, Slovin SF, Concepcion RS, Freedland SJ, Gomella LG, Karsh L, Keane TE, Maroni P, Penson D, Petrylak DP, Ross A, Mouraviev V, Reiter RE, Divgi C, Yu EY; Prostate Cancer Radiographic Assessments for Detection of Advanced Recurrence (RADAR III) Group. J Urol. 2018 Aug 2. pii: S0022-5347(18)43643-9. doi: 10.1016/j.juro.2018.05.164. [Epub ahead of print] Review. PMID: 30077557

The effect of digital rectal exam on the 4Kscore for aggressive prostate cancer. Maccini MA, Westfall NJ, Van Bokhoven A, Lucia MS, Poage W, Maroni PD, Wilson SS, Glodé LM, Arangua P, Newmark J, Steiner M, Werahera PN, Crawford ED. Prostate. 2018 May; 78(7):506-511. doi: 10.1002/pros.23495. Epub 2018 Feb 19. PMID: 29460452

Adolescent and Young Adult Testicular Germ Cell Tumors: Special Considerations. Saltzman AF, Cost NG. Adv Urol. 2018 Jan 31; 2018:2375176. doi: 10.1155/2018/2375176. eCollection 2018. Review. PMID: 29662516

Can a Modified Bosniak Classification System Risk Stratify Pediatric Cystic Renal Masses? Saltzman AF, Carrasco A Jr, Colvin AN, Meyers ML, Cost NG. J Urol. 2018 Aug; 200(2):434-439. doi: 10.1016/j.juro.2018.03.076. Epub 2018 Mar 20. PMID: 29572157

A Multicenter Retrospective Review of Pediatric Leydig Cell Tumor of the Testis. Luckie TM, Danzig M, Zhou S, Wu H, Cost NG, Karaviti L, Venkatramani R. J Pediatr Hematol Oncol. 2018 Mar 16. doi: 10.1097/MPH.0000000000001124. [Epub ahead of print]. PMID: 29554024

The classification of pediatric and young adult renal cell carcinomas registered on the Children's Oncology Group (COG) protocol AREN03B2 after focused genetic testing. Cajaiba MM, Dyer LM, Geller JI, Jennings LJ, George D, Kirschmann D, Rohan SM, Cost NG, Khanna G, Mullen EA, Dome JS, Fernandez CV, Perlman EJ. Cancer. 2018 Jun 15. doi: 10.1002/cncr.31578. [Epub ahead of print] PMID: 29905933

Metastatic Pheochromocytoma in an Asymptomatic 12-Year-Old With von Hippel-Lindau Disease. Colvin A, Saltzman AF, Walker J, Bruny J, Cost NG. Urology. 2018 Mar 12. pii: S0090-4295(17)31324-9. doi: 10.1016/j.urology.2017.12.007. [Epub ahead of print]. PMID: 29545044

Current Treatment of Pediatric Bladder and Prostate Rhabdomyosarcoma. Saltzman AF, Cost NG. Curr Urol Rep. 2018 Feb 22; 19(1):11. doi: 10.1007/s11934-018-0761-8. Review. PMID: 29468476

Adolescent testicular microlithiasis: A case-based, multinational survey of clinical management practices. Brodie KE, Saltzman AF, Cost NG. J Pediatr Urol. 2018 Apr; 14(2):151.e1-151.e8. doi: 10.1016/j.jpurol.2017.12.007. Epub 2018 Jan 31. PMID: 29428360

Initial Imaging for Pediatric Renal Tumors: An Opportunity for Improvement. Saltzman AF, Carrasco A Jr, Weinman J, Meyers ML, Cost NG. J Urol. 2018 May; 199(5):1330-1336. doi: 10.1016/j.juro.2017.11.076. Epub 2017 Nov 24. PMID: 29180299

Patterns of lymph node sampling and the impact of lymph node density in favorable histology Wilms tumor: An analysis of the national cancer database. Saltzman AF, Carrasco A Jr, Amini A, Aldrink JH, Dasgupta R, Gow KW, Glick RD, Ehrlich PF, Cost NG. J Pediatr Urol. 2018 Apr; 14(2):161.e1-161.e8. doi: 10.1016/j.jpurol.2017.09.025. Epub 2017 Oct 31. PMID: 29133167

Timing of Radiation Therapy in Pediatric Wilms Tumor: A Report from the National Cancer Database. Stokes CL, Stokes WA, Kalapurakal JA, Paulino AC, Cost NG, Cost CR, Garrington TP, Greffe BS, Roach JP, Bruny JL, Liu AK. Int J Radiat Oncol Biol Phys. 2018 Jun 1; 101(2):453-461. doi: 10.1016/j.ijrobp.2018.01.110. Epub 2018 Feb 6. PMID: 29559286

Incidental Discovery of Adenocarcinoma of an Augmented Bladder in a Patient with Myelomenigocele Undergoing Cystolithotomy. Islam MM, Saltzman AF, Carrasco A Jr, Higuchi T. Urology. 2018 Mar; 113:203-205. doi: 10.1016/j.urology.2017.11.027. Epub 2017 Nov 28. PMID: 29196068

Effect of Intravesical Instillation of Gemcitabine vs Saline Immediately Following Resection of Suspected Low-Grade Non-Muscle-Invasive Bladder Cancer on Tumor Recurrence: SWOG S0337 Randomized Clinical Trial. Messing EM, Tangen CM, Lerner SP, Sahasrabudhe DM, Koppie TM, Wood DP Jr, Mack PC, Svatek RS, Evans CP, Hafez KS, Culkin DJ, Brand TC, Karsh LI, Holzbeierlein JM, Wilson SS, Wu G, Plets M, Vogelzang NJ, Thompson IM Jr. JAMA. 2018 May 8; 319(18):1880-1888. doi: 10.1001/jama.2018.4657. PMID: 29801011

The effect of digital rectal exam on the 4Kscore for aggressive prostate cancer. Maccini MA, Westfall NJ, Van Bokhoven A, Lucia MS, Poage W, Maroni PD, Wilson SS, Glodé LM, Arangua P, Newmark J, Steiner M, Werahera PN, Crawford ED. Prostate. 2018 May; 78(7):506-511. doi: 10.1002/pros.23495. Epub 2018 Feb 19. PMID: 29460452

Prospective Outcome Analysis of the Safety and Efficacy of Partial and Complete Cryoablation in Organ-confined Prostate Cancer. Barqawi AB, Huebner E, Krughoff K, O'Donnell CI. Urology. 2018 Feb; 112:126-131. doi: 10.1016/j.urology.2017.10.029. Epub 2017 Nov 7. PMID: 29126844

Patients with disorders of sex development and proximal hypospadias are at high risk for reoperation. Saltzman AF, Carrasco A Jr, Colvin A, Campbell JB, Vemulakonda VM, Wilcox D. World J Urol. 2018 May 31. doi: 10.1007/s00345-018-2350-3. [Epub ahead of print]. PMID: 29855697

Incidence and risk factors for positive urine culture at the time of pediatric urologic surgery. Maccini MA, Chalmers DJ, Vemulakonda VM, Campbell JB. Int Urol Nephrol. 2018 Jun; 50(6):1017-1020. doi: 10.1007/s11255-018-1884-z. Epub 2018 May 21. PMID: 29785658

Commentary to 'Laparoscopic inguinal hernia repair by modified peritoneal leaflet closure: Description and initial results in children'. Campbell JB. J Pediatr Urol. 2018 Jun; 14 (3):273. doi: 10.1016/j.jpurol.2018.03.007. Epub 2018 Apr 12. No abstract available. PMID: 29716814

“Minimally invasive research?" Use of the electronic health record to facilitate research in pediatric urology. Vemulakonda VM, Bush RA, Kahn MG. J Pediatr Urol. 2018 Jun 9. pii: S1477-5131(18)30270-5. doi: 10.1016/j.jpurol.2018.04.033. [Epub ahead of print] Review. PMID: 29929853

Prospective study of enhanced recovery after surgery protocol in children undergoing reconstructive operations. Rove KO, Brockel MA, Saltzman AF, Dönmez MI, Brodie KE, Chalmers DJ, Caldwell BT, Vemulakonda VM, Wilcox DT. J Pediatr Urol. 2018 Jun; 14 (3):252.e1-252.e9. doi: 10.1016/j.jpurol.2018.01.001. Epub 2018 Feb 2. PMID: 29398586

Trends in pediatric urologic consultations in a tertiary care hospital setting. Rove KO, Warncke JC, Vemulakonda VM. J Pediatr Urol. 2018 Feb; 14 (1):12.e1-12.e8. doi: 10.1016/j.jpurol.2017.07.005. Epub 2017 Aug 9. PMID: 28826658

Fewer Recurrences with Immediate versus Delayed Intravesical Mitomycin C: A Prospective Randomized European Trial. Wilson SS, Crawford ED. Eur Urol. 2018 Feb; 73(2):233-235. doi: 10.1016/j.eururo.2017.09.014. Epub 2017 Sep 28. No abstract available. PMID: 28967551


2017

Decipher test impacts decision making among patients considering adjuvant and salvage treatment after radical prostatectomy: Interim results from the Multicenter Prospective PRO-IMPACT study. Gore JL, du Plessis M, Santiago-Jiménez M, Yousefi K, Thompson DJS, Karsh L, Lane BR, Franks M, Chen DYT, Bandyk M, Bianco FJ Jr, Brown G, Clark W, Kibel AS, Kim HL, Lowrance W, Manoharan M, Maroni P, Perrapato S, Sieber P, Trabulsi EJ, Waterhouse R, Davicioni E, Lotan Y, Lin DW. Cancer. 2017 Aug 1; 123(15):2850-2859. doi: 10.1002/cncr.30665. Epub 2017 Apr 19. PMID: 28422278

Transurethral Instillation Procedure in Adult Male Mouse. Lee S, Carrasco A Jr, Meacham RB, Malykhina AP. J Vis Exp. 2017 Nov 2;(129). doi: 10.3791/56663. PMID: 29155777

Patient characterization and usage trends of proton beam therapy for localized prostate cancer in the United States: A study of the National Cancer Database. Amini A, Raben D, Crawford ED, Flaig TW, Kessler ER, Lam ET, Maroni P, Pugh TJ. Urol Oncol. 2017 Jun; 35(6):438-446. doi: 10.1016/j.urolonc.2017.01.013. Epub 2017 Feb 15. PMID: 28214281

Impact of Regular Cannabis Use on Biomarkers of Lower Urinary Tract Function. Nedumaran B, Rudra P, Gaydos J, Kumar S, Meacham RB, Burnham EL, Malykhina AP. Urology. 2017 Nov; 109:223.e9-223.e16. doi: 10.1016/j.urology. 2017.08.011. Epub 2017 Aug 18. PMID: 28827195

Current state of renal tumor surgery among pediatric surgeons and pediatric urologists: A survey of American Pediatric Surgical Association (APSA) and Society for Pediatric Urology (SPU) members. Cost NG, Aldrink JH, Saltzman AF, Dasgupta R, Gow KW, Glick R, Ehrlich PF. J Pediatr Urol. 2018 Apr;14(2):168.e1-168.e8. doi: 0.1016/j.jpurol.2017.11.005. Epub 2017 Dec 2. PMID: 29246796

DICER1-related Sertoli-Leydig cell tumor and gynandroblastoma: Clinical and genetic findings from the International Ovarian and Testicular Stromal Tumor Registry. Schultz KAP, Harris AK, Finch M, Dehner LP, Brown JB, Gershenson DM, Young RH, Field A, Yu W, Turner J, Cost NG, Schneider DT, Stewart DR, Frazier AL, Messinger Y, Hill DA. Gynecol Oncol. 2017 Dec; 147(3):521-527. doi: 10.1016/j.ygyno.2017.09.034. Epub 2017 Oct 14. PMID: 29037807

Imaging of renal medullary carcinoma in children and young adults: a report from the Children's Oncology Group. Sandberg JK, Mullen EA, Cajaiba MM, Smith EA, Servaes S, Perlman EJ, Geller JI, Ehrlich PF, Cost NG, Dome JS, Fernandez CV, Khanna G. Pediatr Radiol. 2017 Nov; 47(12):1615-1621. doi: 10.1007/s00247-017-3926-6. Epub 2017 Jul 8. PMID: 28689245

Current Management for Pediatric Urologic Oncology. Caldwell BT, Wilcox DT, Cost NG. Adv Pediatr. 2017 Aug;64(1):191-223. doi: 10.1016/j.yapd.2017.04.001. Review. No abstract available. PMID: 28688589

Patterns of care and survival outcomes for adolescent and young adult patients with testicular seminoma in the United States: A National Cancer Database analysis. Stokes W, Amini A, Maroni PD, Kessler ER, Stokes C, Cost CR, Greffe BS, Garrington TP, Liu AK, Cost NG. J Pediatr Urol. 2017 Aug; 13(4):386.e1-386.e7. doi: 10.1016/j.jpurol.2016.12.009. Epub 2017 Jan 17. PMID: 28153774

Reliability of intraoperative frozen section for the diagnosis of renal tumors suspicious for malignancy in children and adolescents. Carrasco A Jr, Caldwell BT, Cost CR, Greffe BS, Garrington TP, Bruny JL, Black JO, Cost NG. Pediatr Blood Cancer. 2017 Aug; 64(8). doi: 10.1002/pbc.26458. Epub 2017 Jan 18. PMID: 28097784

Large Cystic Metanephric Adenoma in a 15-Year-Old Girl. Saltzman AF, Carrasco A Jr, Maccini MA, Caldwell BT, Treece AL, b. Urology. 2017 Mar; 101:147-150. doi: 10.1016/j.urology.2016.12.019. Epub 2016 Dec 21. PMID: 28011277

Patterns of Performance of Oncologic Surgery by North American Pediatric Urologists: A Report from the Pediatric Urologic Oncology Working Group of the Society for Pediatric Urology. Cost NG, Ross JH, Ferrer FA, Lorenzo AJ, Shnorhavorian M, Routh JC, Kieran K, Ritchey ML. J Urol. 2017 May; 197(5):1349-1354. doi: 10.1016/j.juro.2016.12.011. Epub 2016 Dec 13. PMID: 27986529

Systematic review of bladder cancer outcomes in patients with spina bifida. Rove KO, Husmann DA, Wilcox DT, Vricella GJ, Higuchi TT. J Pediatr Urol. 2017 Oct; 13(5):456.e1-456.e9. doi: 10.1016/j.jpurol.2017.05.006. Epub 2017 Jun 1. Review. PMID: 28687411

Primary non-transecting bulbar urethroplasty long-term success rates are similar to transecting urethroplasty. Anderson KM, Blakely SA, O'Donnell CI, Nikolavsky D, Flynn BJ. Int Urol Nephrol. 2017 Jan; 49(1):83-88. doi: 10.1007/s11255-016-1454-1. Epub 2016 Nov 14. PMID: 27844407

Seventy-Year-Old Man with Large Bladder Mass: Diagnostic and Clinical Challenges of an Uncommon Neoplasm. Lhungay TP, Colvin A, Warncke J, Somerset H, Wilson SS, La Rosa FG. Oncology (Williston Park). 2017 Mar 15; 31(3):210-2, 218-20. Review. No abstract available. PMID: 28299758

How the brain controls urination. Malykhina AP. Elife. 2017 Dec 4; 6. pii: e33219. doi: 10.7554/eLife.33219. PMID: 29199949

Altered expression and modulation of the two-pore-domain (K2P) mechanogated potassium channel TREK-1 in overactive human detrusor. Pineda RH, Nedumaran B, Hypolite J, Pan XQ, Wilson S, Meacham RB, Malykhina AP. Am J Physiol Renal Physiol. 2017 Aug 1;313(2):F535-F546. doi: 10.1152/ajprenal.00638.2016. Epub 2017 May 24. PMID: 28539337 Neuro-tracing approach to study kidney innervation: a technical note. Lee S, Malykhina AP. Kidney Res Clin Pract. 2017 Mar; 36(1):86-94. doi: 10.23876/j.krcp.2017.36.1.86. Epub 2017 Mar 31. PMID: 28393001

Genitourinary and gastrointestinal co-morbidities in children: The role of neural circuits in regulation of visceral function. Malykhina AP, Brodie KE, Wilcox DT. J Pediatr Urol. 2017 Apr; 13(2):177-182. doi: 10.1016/j.jpurol.2016.04.036. Epub 2016 Jun 15. Review. PMID: 28392009

Urinary Biomarkers in Women with Refractory Urgency Urinary Incontinence Randomized to Sacral Neuromodulation versus OnabotulinumtoxinA Compared to Controls. Richter HE, Moalli P, Amundsen CL, Malykhina AP, Wallace D, Rogers R, Myers D, Paraiso M, Albo M, Shi H, Nolen T, Meikle S, Word RA; Pelvic Floor Disorders Network. J Urol. 2017 Jun; 197(6):1487-1495. doi: 10.1016/j.juro.2017.01.037. Epub 2017 Jan 13. PMID: 28089729

Urinary neurotrophic peptides in postmenopausal women with and without overactive bladder. Pennycuff JF, Schutte SC, Hudson CO, Karp DR, Malykhina AP, Northington GM. Neurourol Urodyn. 2017 Mar; 36(3):740-744. doi: 10.1002/nau.23011. Epub 2016 Apr 6. PMID: 27062604

The impact of pontine disease on lower urinary tract symptoms in patients with multiple sclerosis. Weissbart SJ, Pechersky D, Malykhina A, Bavaria T, Parrillo L, Arya LA, Bilello M, Wein AJ, Smith AL. Neurourol Urodyn. 2017 Feb;36(2):453-456. doi: 10.1002/nau.22953. Epub 2016 Jan 6. PMID: 26741487

Long-term outcomes of cutaneous vesicostomy in patients with neuropathic bladder caused by spina bifida. Dönmez Mİ, Carrasco A Jr, Saltzman AF, Vemulakonda V, Wilcox DT. J Pediatr Urol. 2017 Dec; 13(6):622.e1-622.e4. doi: 10.1016/j.jpurol.2017.05.015. Epub 2017 Jun 16. PMID: 28669586

Caudal analgesia, hypospadias, and urethrocutaneous fistula: Does association mean causality? Polaner DM, Almenrader N, Vemulakonda V. Paediatr Anaesth. 2017 Jul; 27(7):676-677. doi: 10.1111/pan.13167. No abstract available. PMID: 28585401

Preventative effects of a HIF inhibitor, 17-DMAG, on partial bladder outlet obstruction-induced bladder dysfunction. Iguchi N, Dönmez Mİ, Malykhina AP, Carrasco A Jr, Wilcox DT. Am J Physiol Renal Physiol. 2017 Nov 1; 313(5):F1149-F1160. doi: 10.1152/ajprenal.00240.2017. Epub 2017 Aug 2. PMID: 28768664

Current Management for Pediatric Urologic Oncology. Caldwell BT, Wilcox DT, Cost NG. Adv Pediatr. 2017 Aug; 64(1):191-223. doi: 10.1016/j.yapd.2017.04.001. Review. No abstract available. PMID: 28688589


2016

The transcription factor SPDEF suppresses prostate tumor metastasis. Steffan JJ, Koul S, Meacham RB, Koul HK. J Biol Chem. 2016 Sep 23; 291(39):20826. doi: 10.1074/jbc.A112.379396. No abstract available. PMID: 27664067

Survival outcomes of adolescent and adult patients with non-seminomatous testicular germ-cell tumors: A population-based study. Amini A, Waxweiler TV, Maroni PD, Kessler ER, Cost CR, Greffe BS, Garrington TP, Liu AK, Cost NG. J Pediatr Urol. 2016 Dec; 12(6):405.e1-405.e9. doi: 10.1016/j.jpurol.2016.06.014. Epub 2016 Aug 6. PMID: 27544905

Pathologic Risk Factors for Metastatic Disease in Postpubertal Patients With Clinical Stage I Testicular Stromal Tumors. Rove KO, Maroni PD, Cost CR, Fairclough DL, Giannarini G, Harris AK, Schultz KA, Cost NG. Urology. 2016 Nov; 97:138-144. doi: 10.1016/j.urology.2016.06.066. Epub 2016 Aug 15. Review. PMID: 27538802

NCCN Guidelines Insights: Prostate Cancer Early Detection, Version 2.2016. Carroll PR, Parsons JK, Andriole G, Bahnson RR, Castle EP, Catalona WJ, Dahl DM, Davis JW, Epstein JI, Etzioni RB, Farrington T, Hemstreet GP 3rd, Kawachi MH, Kim S, Lange PH, Loughlin KR, Lowrance W, Maroni P, Mohler J, Morgan TM, Moses KA, Nadler RB, Poch M, Scales C, Shaneyfelt TM, Smaldone MC, Sonn G, Sprenkle P, Vickers AJ, Wake R, Shead DA, Freedman-Cass DA. J Natl Compr Canc Netw. 2016 May; 14(5):509-19. PMID: 27160230

Diffuse reflectance spectroscopy can differentiate high grade and low grade prostatic carcinoma. Werahera PN, Jasion EA, Crawford ED, Lucia MS, van Bokhoven A, Sullivan HT, Kim FJ, Maroni PD, Port JD, Daily JW, La Rosa FG. Conf Proc IEEE Eng Med Biol Soc. 2016 Aug; 2016:5148-5151. doi: 10.1109/EMBC.2016.7591886. PMID: 28325017

Factors Influencing Overall Survival of Children, Adolescents and Young Adults with High Risk Renal Tumors. Islam M, Saltzman AF, Amini A, Carrasco A Jr, Cost NG. Urology. 2018 Aug 1. pii: S0090-4295(18)30795-7. doi: 10.1016/j.urology.2018.07.032. [Epub ahead of print]. PMID: 30076944

Development of a postoperative care pathway for children with renal tumors. Saltzman AF, Warncke JC, Colvin AN, Carrasco A Jr, Roach JP, Bruny JL, Cost NG. J Pediatr Urol. 2018 May 31. pii: S1477-5131(18)30221-3. doi: 10.1016/ j.jpurol.2018.05.002. [Epub ahead of print]. PMID: 29891188

Monitoring and malignancy concerns in patients with congenital bladder anomalies. Rove KO, Higuchi TT. Curr Opin Urol. 2016 Jul; 26(4):344-50. doi: 10.1097/MOU.0000000000000297. Review. PMID: 27139193

Inter-rater reliability of the APD, SFU and UTD grading systems in fetal sonography and MRI. Chalmers DJ, Meyers ML, Brodie KE, Palmer C, Campbell JB. J Pediatr Urol. 2016 Oct; 12(5):305.e1-305.e5. doi: 10.1016/j.jpurol.2016.06.012. Epub 2016 Jul 27. PMID: 27567594

Basal and stress-activated hypothalamic pituitary adrenal axis function in postmenopausal women with overactive bladder. Smith AL, Hantsoo L, Malykhina AP, File DW, Valentino R, Wein AJ, Sammel MD, Epperson CN. Int Urogynecol J. 2016 Sep; 27(9):1383-91. doi: 10.1007/s00192-016-2988-6. Epub 2016 Mar 4. PMID: 26942596

Pediatric Urology for the General Surgeon. Chalmers DJ, Vemulakonda VM. Surg Clin North Am. 2016 Jun; 96(3):545-65. doi: 10.1016/j.suc.2016.02.010. Review. PMID: 27261794

Association between clean intermittent catheterization and urinary tract infection in infants and toddlers with spina bifida. Kaye IY, Payan M, Vemulakonda VM. J Pediatr Urol. 2016 Oct; 12(5):284.e1-284.e6. doi: 10.1016/ j.jpurol 2016.02.010. Epub 2016 Mar 4. PMID: 27118581

Managing adult urinary incontinence from the congenitally incompetent bladder outlet. Carrasco A Jr, Vemulakonda VM. Curr Opin Urol. 2016 Jul; 26(4):351-6. doi: 10.1097/MOU.0000000000000296. Review. PMID: 27096718

Barriers to participation in surgical randomized controlled trials in pediatric urology: A qualitative study of key stakeholder perspectives. Vemulakonda VM, Jones J.J Pediatr Urol. 2016 Jun; 12(3):180.e1-7. doi: 10.1016/j.jpurol.2015.08.013. Epub 2015 Sep 30. PMID: 26455638

Comparative Outcomes and Perioperative Complications of Robotic Vs Open Cystoplasty and Complex Reconstructions. Cohen AJ, Brodie K, Murthy P, Wilcox DT, Gundeti MS. Urology. 2016 Nov; 97:172-178. doi: 10.1016/ j.urology 2016.06.053. Epub 2016 Jul 18. PMID: 27443464

Long-term urological outcomes in cloacal anomalies. Caldwell BT, Wilcox DT. Semin Pediatr Surg. 2016 Apr; 25(2):108-11. doi: 10.1053/j.sempedsurg.2015.11.010. Epub 2015 Nov 10. Review. PMID: 26969235

Inhibition of HIF Reduces Bladder Hypertrophy and Improves Bladder Function in Murine Model of Partial Bladder Outlet Obstruction. Iguchi N, Malykhina AP, Wilcox DT. J Urol. 2016 Apr; 195(4 Pt 2):1250-6. doi: 10.1016/j.juro.2015.08.001. Epub 2016 Feb 28. PMID: 26926557

Study of clitoral hood anatomy in the pediatric population. Brodie KE, Grantham EC, Huguelet PS, Caldwell BT, Westfall NJ, Wilcox DT. J Pediatr Urol. 2016 Jun; 12(3):177.e1-5. doi: 10.1016/j.jpurol.2015.12.006. Epub 2016 Jan 7. PMID: 26851151


2015

Fertility Preservation Options for Men and Women With Cancer. Skaznik-Wikiel ME, Gilbert SB, Meacham RB, Kondapalli LA. Rev Urol. 2015; 17(4):211-9. PMID: 26839518

NCCN Clinical Practice Guidelines Prostate Cancer Early Detection, Version 2.2015. Carroll PR, Parsons JK, Andriole G, Bahnson RR, Barocas DA, Castle EP, Catalona WJ, Dahl DM, Davis JW, Epstein JI, Etzioni RB, Farrington T, Hemstreet GP 3rd, Kawachi MH, Lange PH, Loughlin KR, Lowrance W, Maroni P, Mohler J, Morgan TM, Nadler RB, Poch M, Scales C, Shaneyfelt TM, Smaldone MC, Sonn G, Sprenke P, Vickers AJ, Wake R, Shead DA, Freedman-Cass D. J Natl Compr Canc Netw. 2015 Dec; 13(12):1534-61. PMID: 26656522

Survival Outcomes of Dose-Escalated External Beam Radiotherapy versus Combined Brachytherapy for Intermediate and High Risk Prostate Cancer Using the National Cancer Data Base. Amini A, Jones B, Jackson MW, Yeh N, Waxweiler TV, Maroni P, Kavanagh BD, Raben D. J Urol. 2016 May; 195(5):1453-8. doi: 10.1016/j.juro.2015.11.005. Epub 2015 Nov 11. PMID: 26576709

Pathologic Risk Factors in Pediatric and Adolescent Patients With Clinical Stage I Testicular Stromal Tumors. Rove KO, Maroni PD, Cost CR, Fairclough DL, Giannarini G, Harris AK, Schultz KA, Cost NG. J Pediatr Hematol Oncol. 2015 Nov; 37(8):e441-6. doi: 10.1097/MPH.0000000000000445. Review. PMID: 26479987

Management of the devastated posterior urethra and bladder neck: refractory incontinence and stenosis. Anderson KM, Higuchi TT, Flynn BJ. Transl Androl Urol. 2015 Feb; 4(1):60-5. doi: 10.3978/j.issn.2223-4683.2015.02.02. Review. PMID: 26816811

Urinary incontinence and pelvic organ prolapse. Anderson KM, Davis K, Flynn BJ. Med Clin North Am. 2015 Mar; 99(2):405-16. doi: 10.1016/j.mcna.2014.11.011. Epub 2014 Dec 23. Review. PMID: 25700591

Prospective study of the Transurethral Suprapubic endo-Cystostomy (T-SPEC(®)): an 'inside-out' approach to suprapubic catheter insertion. Flynn BJ, Larke RJ, Knoll PB, Anderson KM, Siomos VJ, Windsperger AP. Int Urol Nephrol. 2015 Feb; 47(2):257-62. doi: 10.1007/s11255-014-0884-x. Epub 2014 Nov 26.

Lymphoepithelioma-Like Carcinoma of the Urinary Bladder. Kessler ER, Amini A, Wilson SS, Breaker K, Raben D, La Rosa FG. Oncology (Williston Park). 2015 Jun; 29(6):462, C3. No abstract available. PMID: 26089221

Inter-rater reliability of postnatal ultrasound interpretation in infants with congenital hydronephrosis. Vemulakonda VM, Wilcox DT, Torok MR, Hou A, Campbell JB, Kempe A. Int Urol Nephrol. 2015 Sep; 47(9):1457-61. doi: 10.1007/ s11255-015-1068-z. Epub 2015 Aug 8. PMID: 26253827

Regulation of urinary bladder function by protein kinase C in physiology and pathophysiology. Hypolite JA, Malykhina AP. BMC Urol. 2015 Nov 4; 15:110. doi: 10.1186/s12894-015-0106-6. Review. PMID: 26538012

Protein kinase C modulates frequency of micturition and non-voiding contractions in the urinary bladder via neuronal and myogenic mechanisms. Hypolite JA, Chang S, Wein AJ, Chacko S, Malykhina AP. BMC Urol. 2015 Apr 21;15:34. doi: 10.1186/s12894-015-0030-9. PMID: 25896919

Factors associated with age at pyeloplasty in children with ureteropelvic junction obstruction. Vemulakonda VM, Wilcox DT, Crombleholme TM, Bronsert M, Kempe A. Pediatr Surg Int. 2015 Sep;31(9):871-7. doi: 10.1007/s00383-015-3748-2. Epub 2015 Jul 5. PMID: 26143412

Clean intermittent catheterization as an initial management strategy provides for adequate preservation of renal function in newborns with persistent cloaca. Chalmers DJ, Rove KO, Wiedel CA, Tong S, Siparsky GL, Wilcox DT. J Pediatr Urol. 2015 Aug; 11(4):211.e1-4. doi: 10.1016/j.jpurol.2015.05.014. Epub 2015 Jun 12. PMID: 26187141

Continuous local anesthetic infusion for children with spina bifida undergoing major reconstruction of the lower urinary tract. Chalmers DJ, Bielsky A, Wild TT, Siparsky GL, Wilcox DT. J Pediatr Urol. 2015 Apr; 11(2):72.e1-5. doi: 10.1016/j.jpurol.2014.10.011. Epub 2015 Mar 7. PMID: 25819374

Distal hypospadias repair in infants without a postoperative stent. Chalmers DJ, Siparsky GL, Wiedel CA, Wilcox DT. Pediatr Surg Int. 2015 Mar; 31(3):287-90. doi: 10.1007/s00383-014-3647-y. Epub 2014 Dec 5. PMID: 25475503