Lab Research

Lab Members

Lab Twitter

Lorraine Davis, PhD

Sherbenou Lab PhD Student Alumni

Lorraine graduated with her PhD from the CU Cancer Biology Program in the Spring of 2024. Her researched focused on studying mechanisms of drug resistance in myeloma, particularly acquired resistance to immunomodulatory drugs (IMiDs). Lorraine is currently pursuing a career biotech, focusing on assay development.

Poster Presentation

Alana Keller

American Society of Hematology Annual Meeting, San Diego 2023

Emma Grace Pittard

Summer Undergraduate 2023

Emma Grace is currently pursuing her bachelor's degree at University of South Carolina. Her summer research project focused on bi-specific antibody drug combinations in multiple myeloma.

Julia Johnson

Gates Institute Summer Intern 2023

Celebrating Summer Undergraduate Internships

August 2023

Poster Presentation

Alana Keller

American Society of Hematology Annual Meeting, New Orleans 2022

Lauren Reiman

Research Professional Emeritus

Lauren left the lab in Spring 2023 after working with us for 3 years. During her time in the lab, Lauren optimized and expanded our drug sensitivity assay My-DST. She also investigated when relapse myeloma patients can be re-treated with the CD38 monoclonal antibody therapy Daratumumab. Lauren is currently attending medical school at the University of Southern California - Los Angeles.

Lab Outing Day 2021

White Water Rafting - Clear Creek, CO

Olivia Pérez de Acha López, MD

Visiting Research Scholar

Olivia Perez de Acha Lopez comes to us from Madrid, Spain. She recently received her MD from Universidad Autonoma de Madrid. Her past research was done at the Hospital Puerta de Hierro studying TKI drug resistance in liquid biopsies from patients with EGFR+ lung adenocarcinoma. Before joining us at CU, Olivia also spent last summer at the NIH studying exosomes as potential biomarkers in Alzheimer's Disease. In our group, she evaluated immunotherapy targets, with a particular focus on the daratumumab-refractory setting. In 2021 Olivia matched for medical residency in Washington D.C.

Eliza Rhee

Summer Intern 2021

Beau Idler

Professional Research Assistant Emeritus

Beau left the lab in June 2020 after working with us for 1 ½ years. During his time in our lab, Beau pioneered our pipeline for testing drug combinations for synergy in cell lines and patient samples. He also made significant contributions to multiple projects through ex vivo drug sensitivity experiments and testing new potential myeloma regimens using in vivo xenograft models. Beau is currently pursuing his MD at the Mayo Clinic in Scottsdale Arizona.

Denis Ohlstrom

Bioinformatics Certificate Program

Denis left the lab in June 2020 after working with us for 1 year. During his time with our group, Denis created a bioinformatics pipeline for processing mass cytometry (CyTOF) data in Rstudio, and analyzing the output via machine learning algorithms. He also conducted our first single cell RNA sequencing experiment to interrogate myeloma subpopulations. After leaving the lab, Denis entered the MD, PhD program at Emory University.

Lab Outing Day 2020

Grey's Peak, 14,278 feet

Axe Throwing

2020

Poster Presentation

American Society of Hematology Annual Meeting, Orlando, 2019

Janet Lee, Visiting Undergraduate

Cancer Research Fellowship Program, Summer 2019

Lab BBQ 2019: Epic Grilled Cheese Party

Lab Outing Day 2018

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New Belgium Brewery Tour, Fort Collins

Mike VanWyngarden

Professional Research Assistant Emeritus

Mike left the lab in December 2018 after working with us for 2 ½ years. During this time, he focused on the development of ex vivo drug sensitivity profiling assay on primary samples which we continue to optimize to measure clinical drug resistance and guide development of new agents for myeloma. This work was recently published in the journal Blood Advances. Mike also conducted multiple in vivo mouse model experiments, including implementation of a technically challenging myeloma patient-derived xenograft model. In addition, Mike generated the firefly luciferase myeloma cell lines that we continue to use in xenograft experiments testing out new drug approaches to this disease. Mike joined the Hematology Clinical Trials Unit at our cancer center as a Clinical Research Coordinator prior to attending the Physician Assistant (PA) program at Colorado Mesa University.

Poster Presentation

American Society of Hematology Annual meeting, San Diego, 2018

Christophe Langouë-Astrie, MS

Biomedical Sciences and Biotechnology Program

Christophe left the lab in May 2017 after completing his master degree program. During his time in our group, he created out initial bioinformatics pipeline for incorporation of publicly available data sets to validate and extend our bench work. In doing so, we helped with a collaborative project with Genentech to analyze the potential of targeting the unfolded protein response (UPR) in myeloma treatment. After completing his master’s degree, Christophe went on to join the Pharmacology PhD program at CU Anschutz.

Lab Outing Day 2017

Mount Bierstadt Summit, 14,065 feet

Andres Arriaga

Visiting High School Student through Denver STaRS Internship Program, Fall 2017

Lab Outing Day 2016

Matthews/Winters Trail at Red Rocks