Makenna Joy May
Research Services Professional (E)
Makenna earned summa cum laude in her BA in Molecular, Cellular, and Developmental Biology and high distinction for her BA in Integrated Physiology with a minor in Ethnic Studies at the University of Colorado, Boulder. She began her scientific career working concurrently with Dr. Joel Kralj and Dr. Javon Carter at the University of Colorado, Boulder where she isolated E. Coli DNA variations in antibiotic resistance using bioinformatics. She then moved onto working under Dr. Isak Tengesdal in Dr. Charles Dinarello’s lab at the University of Colorado, Anschutz School of Medicine. Here, she studied her undergraduate Honors Thesis project inhibiting the NLRP3 inflammasome in metastatic breast cancers using OLT1177 alongside Anti-PD-1 therapy. Makenna also worked alongside Alberto Dinarello to identify a communication between novel IL-38, the WNT pathway, and IL-1β secretion. In this paper submitted to Proceedings of the National Academy of Sciences of the United States of America, Makenna found that IL-38 plays a central role in driving intestinal stem cell differentiation. She also worked as a Medical Assistant at Spine West, a non-surgical physiatry medical practice specializing in physical medicine & rehab of the spine.
As a technician in the Pietras lab, Makenna hopes to gain knowledge and skills in the world of hematology that will help her in her pursuit to become a pediatric hematologist/oncologist by continuing her education in an MD/PhD program in the near future.
Outside of the lab, Makenna enjoys taking care of her cats and plants, painting, volunteering at the Children’s Hospital and other youth programs, and exploring Colorado’s food scene with her friends.