IMAGE Group Current Studies
The ACES Study
(Antihypertensives Combined with Exercise for Seniors)
| Purpose: To learn how different blood pressure medications, combined with exercise, impact functional status and cardiovascular risks in older adults. |
| Now recruiting: Men and women, aged 60+, who do not exercise regularly |
| Investigator: Wendy Kohrt, Ph.D. COMIRB #17-1758 |
| Contact: Gabriel Buxo at gabriel.buxo@cuanschutz.edu or 720-848-6419 |
(Adaptive Responses to Overfeeding and Weight Regain in Reduced Obese Individuals)
| Purpose: A 1-year research study looking at the metabolic adaptations to weight loss and predictors of weight loss maintenance |
| Now recruiting: Weight stable 30-50 year old men and women with a BMI between 30-43 |
| Investigators: Dan Bessesen, M.D. and Corey Rynders, Ph.D. COMIRB# 18-0091 |
| Contact: Sheila Steinke at arrow@cuanscutz.edu |
(The Impact of Estrogen Status on the Biological Function of Brown Adipose Tissue in Women Measured using Quantitative PET/CT)
| Purpose: To learn more about how estrogen affects brown fat and resting metabolic rate |
| Now recruiting: Women, aged 18-80, premenopausal (not pregnant or using contraceptive) OR postmenopausal (no cycle within the last year) |
| Investigator: Edward Melanson, Ph.D. COMIRB# 16-1479 |
| Contact: Toria Crispin at toria.crispin@cuanschutz.edu or 720-316-5218 |
(Bioenergetic Effects of Aging and Menopause)
| Purpose: To learn how menopause changes weight gain and bone health |
| Now recruiting: Premenopausal women between the ages of 18-45, and postmenopausal women <6months and >7 years past their last menstrual cycle. |
| Investigator: Wendy Kohrt, Ph.D. COMIRB # 18-2483 |
| Contact: Victoria Bland, Ph.D. at BEAMstudy@ucdenver.edu or 720-848-6399 |
(Cardiovascular Consequences of Hypogonadism in Men)
| Purpose: To study how the loss of testosterone affects the health of the heart and arteries in men |
| Now recruiting: Men 50-75 years old, in general good health. No history of cancer, diabetes or heart disease. Non- smokers. Cannot be taking testosterone replacement therapy. |
| Investigator: Kerrie Moreau, Ph.D. COMIRB# 15-1162 |
| Contact: Matt Babcock, Ph.D. at moreaulab@cuanschutz.edu or 720-848-6470 |
(DHEA Augmentation of Musculoskeletal Adaptation to Exercise in Older Women)
| Purpose: To learn more about the effects of exercise and the adrenal hormone DHEA on bone density and strength in postmenopausal women with low bone mass (osteopenia) or moderate osteoporosis. |
| Now recruiting: Women, aged 55-85, who are postmenopausal and do weight-bearing exercise less than twice a week. |
| Investigator: Catherine Jankowski, Ph.D. COMIRB# 16-2427 |
| Contact: Jillian Schuberth at jillian.schuberth@cuanschutz.edu |
The HEALTH Study
(High-Intensity Exercise to Attenuate Limitations and Train Habits in Older Adults with HIV)
| Purpose: To learn more what types of exercise improve muscle function and decrease fatigue, and what helps people aging with HIV continue to exercise on their own. |
| Now recruiting: Men and women, aged 50+, who are HIV-positive and sedentary. |
| Investigator: Christine Erlandson, M.D., M.S. COMIRB# 19-1985 |
| Contact: Vincent Khuu at vincent.khuu@cuanschutz.edu or 720-848-7561 |
(Vascular Health After In Vitro Fertilization)
| Purpose: To study vascular function and blood pressure in women following pregnancy |
| Now recruiting: Non-smoking women aged 18-45 years old, in general good health, with a prior pregnancy conceived through either in vitro fertilization (IVF) or unassisted (natural) reproduction. No history of heart disease or stroke. Cannot be taking hormone therapy or blood pressure medication. |
| Investigator: Lyndsey DuBose, Ph.D. COMIRB# 21-2903 |
| Contact: Lyndsey DuBose, Ph.D. at lyndsey.dubose@cuanschutz.edu or 720-848-5596 |
(Molecular Transducers of Physical Activity)
| Purpose: To understand how physical activity improves health and prevents disease |
| Now recruiting: Men and women 18 years of age or older, with a BMI between 19-35, who are either sedentary or exercise regularly (cycling, weight lifting), who have no history of diabetes or heart disease. Please visit motrpac.org/join to learn more. |
| Investigator: Wendy Kohrt, Ph.D. COMIRB #18-0220 |
| Contact: MoTrPAC@UCDENVER.EDU or call 720-848-6408 |
(Ovarian Hormone Regulation of Central and Cerebrovascular Hemodynamics)
| Purpose: To study the role of ovarian hormones (e.g., estrogen) on brain blood vessel function |
| Now recruiting: Non-smoking women aged 45-55 years old, in general good health. No history of heart disease or stroke. Cannot be taking hormone therapy or blood pressure medication.. |
| Investigator: Lyndsey DuBose, Ph.D. COMIRB# 21-3590 |
| Contact: Lyndsey DuBose, Ph.D. at lyndsey.dubose@cuanschutz.edu or 720-848-5596 |
(Risk of Long-Term Vascular Dysfunction in Women with a History of Pregnancy-Induced Hypertension)
| Purpose: To study vascular function in women with a history of pregnancy-induced hypertension |
| Now recruiting: Non-smoking women aged 18-70 years old with a prior pregnancy complicated by gestational hypertension, preeclampsia, eclampsia or toxemia. No history of heart disease. Non-smokers. Cannot be taking hormone therapy or blood pressure medication. |
| Investigator: Kerrie Moreau, Ph.D. COMIRB# 16-2581 |
| Contact: Lyndsey DuBose, Ph.D., at lyndsey.dubose@cuanschutz.edu or 720-848-5596 |
(Skeletal Response to Simulated Night Shift)
| Purpose: To determine how simulated night-shift work affects bone metabolism |
Now recruiting:
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| Investigator: Christine Swanson, M.D, MCR. COMIRB # 20-3013 |
| Contact: spotlight@ucdenver.edu |
(Calibrating free-living physical activity characteristics across functionally limited populations using machine-learned accelerometer approaches)
| Purpose: To develop better equations to estimate calories burned from physical activity monitors among individuals with a wide variety of movement |
| Now recruiting: Individuals 18-100 years old with movement disorders, and can function majority of the day without assistive devices or wheelchair |
| Investigator: Edward Melanson, Ph.D., COMIRB # 16-2706 |
| Contact: movementstudy@cuanschutz.edu |
The VA MIXED Study
| Purpose: To learn more about how exercise and Type 2 Diabetes affect the heart, muscles, and blood vessels. |
Now recruiting:
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| Investigators: Jane Reusch, M.D. and Judy Regensteiner, Ph.D. COMIRB #17-0356 |
| Contact: Deirdre Rafferty at deirdre.rafferty@cuanschutz.edu or 720-848-6688 |
