Background
Viral N. Shah, MD, completed his residency in internal medicine and fellowship in endocrinology, diabetes and metabolism from India. He currently sees patients at Barbara Davis Center for Diabetes at University of Colorado Anschutz Medical Campus.
Research + Funding
In 2015, Dr. Shah received funding from the Ludeman Center for his project aimed at evaluating skeletal health in postmenopausal women with type 1 diabetes. He investigated the association between bone density and cardiovascular risk measures in 46 postmenopausal women with type 1 diabetes and 52 matched controls without diabetes. He discovered that the women with type 1 diabetes had significantly lower bone density at femoral neck and their cardiovascular risk measures, such as pulse wave velocity and carotid intima thickness, were higher than women without diabetes. This data suggested that cardiovascular risk was higher among postmenopausal women with type 1 diabetes than women without.
“My first seed grant by the Ludeman Center led to a career development award (K23) from the National Institutes of Health and I am currently the principal investigator on two NIH funded R01 projects. This success story would not have been possible without the center. I am very appreciative of their leadership, specifically from Wendy Kohrt, PhD, and Judy Regensteiner, PhD, as well as their statistical support, career development and mentorship over the last 10 years.”
Transforming Women’s Health
Dr. Shah’s work is motivated by the fact that risk for fracture and cardiovascular diseases are higher in women with type 1 diabetes. For more to be understood, it takes research of sex differences in pathophysiology, treatment and clinical care. Presently, his research is focused on investigating the effects of type 1 diabetes on bone structural and mechanical properties to improve outcomes in women.