Background
Fabrice Dabertrand, PhD, received his PhD in Neuroscience from the University of Bordeaux in France. where he did his first postdoctoral training. In 2009, he joined the University of Vermont for a second postdoctoral training mentored by Mark Nelson where he developed approaches to study the control of cerebral blood flow in murine microcirculation. This tour de force lets him use genetic mouse models and investigate potential treatments for cerebrovascular diseases. Dr. Dabertrand’s research is dedicated to reducing the gaps in understanding female pathophysiology and drug responsiveness created by historical biases that have favored male experimental models.
Research + Funding
In 2019, Dr. Dabertrand began his Ludeman Center-funded research project titled, “Sex Differences in Hippocampal Vascular Dysfunction after Cardiopulmonary Resuscitation from Cardiac Arrest.” This research stemmed from the understanding that the brain needs an uninterrupted supply of blood-borne nutrients dynamically regulated by intracerebral arterioles. His project proposed to examine sex differences in the control of vascular reactivity and the consequences of the injury caused by cardiac arrest following cardiopulmonary resuscitation. His current research is federally funded and aimed at understanding the disruption of neurovascular coupling in disorders involving extracellular matrix protein alterations to shed light on vascular dementia.
Transforming Women’s Health
His research is designed to reduce gaps in the understanding of female cerebrovascular function and drug responsiveness created by historical biases that have favored male experimental models. As a member of the Ludeman Family Center for Women's Health Research and the Neuroscience Outreach Group, Dr. Dabertrand is dedicated to combat gender bias in research by including sex differences as a variable and by supporting gender equality and enhancing diversity and inclusion in his laboratory.