Background
Anne M. Lynch, MD, MSPH, received her MD from University College Dublin, Ireland, and her MSPH from the University of Colorado. Her work has been greatly inspired by her interest in the role of systemic biomarkers in adverse outcomes of pregnancy and in ocular diseases, specifically to see if there is a difference by sex among patients with age-related macular degeneration (AMD).
Research + Funding
In 2007, Dr. Lynch began her Ludeman Center-funded research project titled, “Antiangiogenic Factors, Complement Activation Fragment Bb and Preeclampsia.” She examined the relationship between antiangiogenic factors and the complement activation fragment Bb with preeclampsia. She demonstrated that obesity was related to the development of preeclampsia and that increased concentrations of Bb and lower concentrations of PiGF were associated with the development of preeclampsia later in pregnancy.
Dr. Lynch has shared that the mentorship and support for early-career faculty from the Ludeman Center helped launch her academic career and supports the advancement of women’s health research.
Transforming Women’s Health
The results of Dr. Lynch’s research revealed the importance of identifying risk factors early in a woman’s life to educate her about the risk of developing preeclampsia which is a risk factor for the development of cardiovascular disease later in life and to raise awareness that lifestyle modifications, such as weight loss or increased physical activity could attenuate this risk. Currently, her research priority is AMD and retinopathy of prematurity with a specific focus on sex differences in systemic biomarkers in patients with AMD.