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High-dose testosterone treatment in transgender individuals represents an important intervention to affirm gender and allow for transition. However, little is known regarding how this treatment affects brain health and cognition related to optimal productivity and function in everyday life. Dr. Novick's study, "My Transgender Brain Study (MyT "Mighty" Brain)", will measure cognitive performance and brain activity in both female-to-male transgender individuals who are undergoing testosterone treatment and those who are not. In understanding how hormone treatments for transgender individuals affect the brain, Dr. Novick aims to promote treatment in the safest, most informed manner possible.