We are a team of researchers led by Dr. Trevor Nydam and Dr. Hunter Moore, where we study coagulation and how it can impair or heal organs after an injury.

Our Mission:

Our mission is to train the next generation of physician-scientists and conduct high-impact research that improves the lives of organ transplant recipients!

Our research focuses on 3 main areas:

1. Global Coagulation Assessment
2. Ex Vivo Perfusion
3. Microfluidics

We have been working on novel solutions to improve organ preservation and graft function while also investigating ways to manage deceased donors to increase availability, and improve organ function and long-term survival. 

We are evaluating the mechanisms that drive fibrinolysis dysfunction in both the recipient and donor organ.  At the same time, we are developing clinical expertise in advance organ recovery strategies.  These include normothermic regional perfusion of the donor (extracorporeal perfusion of abdominal organs) and machine perfusion of the liver after it has been removed from the donor before implant in the donor. These research efforts will not only lead to increasing our graft survival but will also increase the number of organs utilized for transplantation.

Overall, these efforts have the potential to make a large impact on reducing the demand on organs in patients awaiting lifesaving transplants in the setting of end stage liver disease.