Our research aims to identify non-opioid alternatives for the treatment of chronic musculoskeletal pain. Chronic orthopedic pain conditions, such as back pain and knee pain, are highly prevalent and disabling conditions that are often treated with prescription opioids. The number of individuals using opioids for non-cancer chronic pain reached approximately 275 million in 2016. Unfortunately, this increase in opioid use is also associated with opioid abuse and overdose; each day, 90 Americans die from opioid overdose. Thus, there is an urgent need to find alternative treatments to reduce or eliminate opioid use for chronic pain conditions. One such alternative that has gained increased recognition in recent years is medical cannabis. Our lab is currently focused on studying the health effects of cannabis and cannabinoids for chronic musculoskeletal pain.