The biobank uses genetic data and medical record data for both research and clinical testing. Our laboratory currently stores over 100,000 blood and DNA samples from participants. These samples and the genetic data we generate from them are used to research health and disease and may someday lead to discoveries that will change current standards of care. As a CLIA-certified, CAP-accredited clinical laboratory, the biobank is qualified to return medically-actionable genetic test results to participants and their healthcare providers, providing insight and the potential for intervention in genetic disease risk.


We host a highly-skilled team capable of working with campus investigators on numerous analyses of their interest, whether it is to identify cohorts, study specific the genetic basis of various traits or diseases, or explore patterns of risk for individuals in the data. We recognize that not all groups include statistical geneticists, and the team is available for collaboration to ensure genetic and electronic health record analyses are performed using state-of-the-art statistical tools. Over the past few years we have collaborated with numerous groups across the United States as well as internationally on a number of projects, while maintaining appropriate levels of study security.

Clinical Operations

Our ultimate goal is to improve the health and wellness of patients through personalization of care. Our Clinical Operations team works closely with UCHealth, our affiliated health system, to deliver cutting edge medical knowledge directly to patients and their providers using a number of technical and human resource strategies.  Currently, we return two types of clinical genetic test results to biobank participants who have signed an appropriate consent: (1) pharmacogenetic (PGx) results, which are used to inform medication selection and dosing and (2) high-impact pathogenic variant results, which are rare genetic variants that increase the risk of certain diseases, like cancer and heart conditions, for which early intervention and treatment can improve health outcomes. 

PGx results are returned preemptively (I.e., before they may be needed) to a participant’s electronic health record (EHR). Our team has built drug-gene specific clinical decision support tools in the EHR which provide clinicians with pertinent PGx results and clinical guidance at the point-of-prescribing.

High impact pathogenic variant results are returned by a certified genetic counselor.  Discussion with Biobank participants about their genetic variant includes information about the health risks related to this result, review of health care recommendations and discussion of risks and testing options for family members.  Participants have options for notifying their primary care provider and being referred to specialty clinics for follow-up care.  The genetic test result is entered in the EHR and shared with the Biobank participant and their relevant care providers.

Our aim is to establish a multidisciplinary clinic that utilizes personalized medicine as its mode of treatment in collaboration with other schools and colleges of the University. ​​​​

Translational Informatics Service (TIS)

Translational Informatics Service (TIS) within CCPM collaborates with Health Data Compass (HDC) and the CCPM biobank to facilitate integration of biobank genetic/genomic data and UCHealth clinical data from HDC. TIS is a service unit of CCPM. It fulfills requests from the University of Colorado researchers and contracted industry partners and creates tools and datasets for the use by the research community as well as develop tools to help facilitate return of clinical results. TIS promotes clinical and translational genetics and genomics research performed by CU faculty and facilitates collaboration with current and future CCPM and UCHealth partners including those contracted from biotechnology and pharmaceutical industries.