Projects

By combining in vivoanimal models of ischemic/traumatic brain injury, neurophysiology, neurobehavioral, histological and molecular approaches, the Neuronal Injury team hopes to identify targets to improve functional outcome after an insult to the brain.

Current projects in our lab focus on on channel involvement in injury, with a particular emphasis on synaptic plasticity deficits in the hippocampus and cerebellum. We combine this with in vivo pharmacological and genetic manipulations to improve memory or motor function. We also study the contribution of age-dependent neuronal and glial responses to differences in recovery between juveniles and adults.

Molecular and Biochemistry

Molecular and Biochemistry

Histology

Histology

Viral Tracing

Viral Tracing

Electrophysiology-whole cell patch clamp

Electrophysiology

Whole cell patch clamp

Electrophysiology- Field recordings (1)

Electrophysiology

Field recordings

Optogenetics

Optogenetics

Behavior

Behavior

Techniques


Mouse Models

Cardiac Arrest, Cardio Pulmonary Resuscitation (CA-CPR)

Middle Cerebral Artery Occlusion (MCAO)

Middle Cerebral Artery Occlusion (MCAO)

Cardiac Arrest_Cardio Pulmonary Resuscitation (CA-CPR)

Photo-thrombosis

Traumatic Brain Injury (TBI)

Traumatic Brain Injury (TBI)

Photo-thrombosis

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