jimeno research lab

The Jimeno lab aims to bridge lab and clinical research by developing direct patient xenograft models of head and neck and other cancers to generate better cancer models and as a platform to study cancer stem cells and devising ways to integrate that knowledge into clinical trials to individualize anti-cancer therapy.

selected publications

Weaver AN, Jimeno A. Zanubrutinib: a new BTK inhibitor for treatment of relapsed/refractory mantle cell lymphoma. Drugs Today (Barc). 2020 Aug;56(8):531-539. doi: 10.1358/dot.2020.56.8.3158047. PMID: 33025948.

Gomez KE, Wu F, Keysar SB, Morton JJ, Miller B, Chimed TS, Le PN, Nieto C, Chowdhury FN, Tyagi A, Lyons TR, Young CD, Zhou H, Somerset HL, Wang XJ, Jimeno A. Cancer Cell CD44 Mediates Macrophage/Monocyte-Driven Regulation of Head and Neck Cancer Stem Cells. Cancer Res. 2020 Oct 1;80(19):4185-4198. doi: 10.1158/0008-5472.CAN-20-1079. Epub 2020 Aug 14. PMID: 32816856.

Morton JJ, Alzofon N, Jimeno A. The humanized mouse: Emerging translational potential. Mol Carcinog. 2020 Jul;59(7):830-838. doi: 10.1002/mc.23195. Epub 2020 Apr 10. PMID: 32275343.

Alzofon N, Jimeno A. Avapritinib for metastatic or unresectable gastrointestinal stromal tumors. Drugs Today (Barc). 2020 Sep;56(9):561-571. doi: 10.1358/dot.2020.56.9.3170808. PMID: 33025950.

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