Traci Lyons, Phd, and Virginia Borges, MD, MMSc are evaluating Pearl-01, an antibody that targets the protein semaphorin 7A, in advance of a first-in-human clinical trial.
Developed at CU Anschutz, the therapy targets two pathways that help tumors grow and evade the immune system. The trial will assess the therapy’s safety and ability to attack cancer in patients.
Laura Graham, MD, is the site PI for the potentially game changing immunotherapy drug trials of a bispecific T-cell engager that links a protein on a T cell with a protein on the tumor.
Through a five-year grant, oncologist Marie Wood, MD, aims to promote clinical trials that are focused on preventing cancer and improving outcomes for survivors.