Flaig Research Lab

McCullagh 1200

Research Focus

Genitourinary Cancer Translational Research

Selected Publications

Functionalized gold nanorods for thermal ablation treatment of bladder cancer.  Cho SK, Emoto K, Su LJ, Yang X, Flaig TW, Park W.   J Biomed Nanotechnol. 2014 Jul;10(7):1267-76.   PMID: 24804547

Simultaneous activation of Kras and inactivation of p53 induces soft tissue sarcoma and bladder urothelial hyperplasia.   Yang X, La Rosa FG, Genova EE, Huber K, Schaack J, Degregori J, Serkova NJ, Li Y, Su LJ, Kessler E, Flaig TW.  PLoS One. 2013 Sep 18;8(9):e74809. doi: 10.1371/journal.pone.0074809.  PMID: 24058630

Diphtheria toxin-epidermal growth factor fusion protein DAB389EGF for the treatment of bladder cancer.  Yang X, Kessler E, Su LJ, Thorburn A, Frankel AE, Li Y, La Rosa FG, Shen J, Li CY, Varella-Garcia M, Glodé LM, Flaig TW.  Clin Cancer Res. 2013 Jan 1;19(1):148-57. doi: 10.1158/1078-0432.CCR-12-1258.  PMID: 23172881

​miR-125b Regulation of Androgen Receptor Signaling Via Modulation of the Receptor Complex Co-Repressor NCOR2.  Yang X, Bemis L, Su LJ, Gao D, Flaig TW.   Biores Open Access. 2012 Apr;1(2):55-62. doi: 10.1089/biores.2012.9903.  PMID: 23514806​

Dual epidermal growth factor receptor and vascular endothelial growth factor receptor inhibition with vandetanib sensitizes bladder cancer cells to cisplatin in a dose- and sequence-dependent manner.   Flaig TW, Su LJ, McCoach C, Li Y, Raben D, Varella-Garcia M, Bemis LT.   BJU Int. 2009 Jun;103(12):1729-37. doi: 10.1111/j.1464-410X.2009.08367.x.  PMID: 19220256

A study of high-dose oral silybin-phytosome followed by prostatectomy in patients with localized prostate cancer.  Flaig TW, Glodé M, Gustafson D, van Bokhoven A, Tao Y, Wilson S, Su LJ, Li Y, Harrison G, Agarwal R, Crawford ED, Lucia MS, Pollak M.  Prostate. 2010 Jun 1;70(8):848-55. doi: 10.1002/pros.21118.  PMID: 20127732

Silibinin synergizes with mitoxantrone to inhibit cell growth and induce apoptosis in human prostate cancer cells.   Flaig TW, Su LJ, Harrison G, Agarwal R, Glodé LM. Int J Cancer. 2007 May 1;120(9):2028-33.   PMID: 17230508

Lab Personnel

Thomas Flaig, MD 
Associate Professor 

Principle Investigator

Peter Boxley
Professional Research Assistant​

Gregory Osborne, MS 
Professional Research Assistant​

Maren Salzmann-Sullivan, MS
Professional Research Assistant

Cristi Semmler, BS
Professional Research Assistant​

Lih-Jen Su, MS 
Senior Research Instructor
Lab Manager​