FIG Service Core

      High Throughput Imaging/Screening


Cell-based fibrosis assays

  TGFb1 stimulated myofibroblast differentiation

•Alpha smooth muscle actin (aSMA) primary readout
•Secondary readouts (e.g. collagen): cell-dependent
•Current assays: Adult rat ventricular fibroblasts (ARVF), normal human cardiac fibroblasts (NHCF), normal human lung fibroblast (NHLF)
Custom assay development possible with your cells

(Ask about our free initial evaluation)

 

Small molecule collection (~ 3,000)

•FDA & internationally approved drugs
•Target selective (e.g. kinase)

              •Epigenetic


     Tim McKinsey, Ph.D. (FIG Director)

     Timothy.McKinsey@cuanschutz.edu                       CFReT member discount available


FIG service center