Aaron Johnson, PhD
Specialty
Molecular Oncology
Location
University of Colorado Anschutz Medical Campus
Objective
The overall goal of this project is to understand the molecular mechanisms of chromatin-interacting long noncoding RNAs in gene silencing that contribute to cancer progression.
Description
The student will initially work closely with members of the laboratory to then develop a discrete project studying the biochemistry and molecular biology of a cancer-associated RNA that transits through the nucleus to repress gene expression.
Our work focuses on certain members of this trans-acting RNA family that can either contribute to the pathways that defend against cancer, or have been show to drive tumor development and metastasis.