Yeager Lab at the Linda Crnic Institute for Down Syndrome

Lab Mission

The primary goal of the Yeager Lab is to understand how the lung vasculature (blood and lymphatic) operates during episodes of acute and chronic inflammation. The Yeager Lab examines lung tissue and peripheral blood immune cells from patients with pulmonary hypertension, including persons with Down syndrome.

Collaborations and Tools

The Yeager Lab enjoys long-standing collaborations with the Departments of Immunology, Pulmonary Critical Care, Pediatrics, and Cardiology. Dr. Yeager is a member of the Academy of Medical Educators and has received several teaching awards. Currently, the lab is seeking students and fellows for NIH funded positions to study lung inflammation.

Work We Do

We optimize pre-clinical and three-dimensional cell culture models to test potential therapies that limit chronic inflammation in the lung and the right ventricle.