Research


Research by Faculty Member

Christine Huang, PhD

Christene Huang, PhD

The Huang laboratory studies transplantation immunology with a focus on developing clinically relevant protocols for the establishment of transplantation tolerance.

Brooke French, MD

Brooke French, MD

Dr. French's interests include outcome analysis of craniofacial surgery using 3D imaging technology and anthropometric software.

Tae Chong, MD

Tae Chong, MD

Current research projects:

  • Breast Reconstruction
  • Keloids
  • Hand Transplantation

David Mathes, MD

David Mathes, MD

Current research projects:

  • Tolerance to Vascularized Composite Tissue Allografts (VCA) via only Transient Donor Cell Chimerism in a Pre-Clinical Large Animal Model
  • Tolerance to Composite Tissue Allografts via Hematopoietic Stem Cell Infusion

Christodoulos Kaoutzanis, MD

191007_ChristodoulosKaoutzanis_web

Current research projects:

  • Breast Reconstruction
  • Transgender Surgery


Publications


2019

Patient Safety in Microvascular Plastic Surgery. Colakoglu S, Tebockhorst S, Chong TW, Mathes DW. J Reconstr Microsurg. 2019 Nov;35(9):631-639. doi: 10.1055/s-0039-1693142. Epub 2019 Jul 21. PMID: 31327160

Analysis of Keloid Response to 5-Fluorouracil Treatment and Long-Term Prevention of Keloid Recurrence. LaRanger R, Karimpour-Fard A, Costa C, Mathes D, Wright WE, Chong T. Plast Reconstr Surg. 2019 Feb;143(2):490-494. doi: 10.1097/PRS.0000000000005257. PMID: 30531622

Targeted Muscle Reinnervation: Outcomes in Treating Chronic Pain Secondary to Extremity Amputation and Phantom Limb Syndrome. McNamara CT, Iorio ML. J Reconstr Microsurg. 2019 Nov 5. doi: 10.1055/s-0039-1700559. [Epub ahead of print] PMID: 31689720

Coronary Artery Disease Association With Arterial Calcifications on Routine Hand Radiographs. Taylor EM, Wu WW, Ruan Q, Hall EC, Giladi AM, Iorio ML. J Hand Surg Am. 2019 Oct 30. pii: S0363-5023(19)31392-9. doi: 10.1016/j.jhsa.2019.10.004. [Epub ahead of print] PMID: 31677909

Vascularized Osteochondral Grafts: Histologic Evaluation of Chondrocyte Viability with Viable Hyaline Nonfibrous Cartilage. Freniere BB, Giladi AM, Iorio ML. J Hand Microsurg. 2019 Oct;11(Suppl 1):S26-S30. doi: 10.1055/s-0038-1675886. Epub 2018 Dec 11. PMID: 31616123

Choosing between Muscle and Fasciocutaneous Free Flap Reconstruction in the Treatment of Lower Extremity Osteomyelitis: Available Evidence for a Function-Specific Approach. Kovar A, Colakoglu S, Iorio ML. J Reconstr Microsurg. 2019 Oct 7. doi: 10.1055/s-0039-1698469. [Epub ahead of print] PMID: 31590192

Hand, Wrist, Forearm, and Arm Replantation. Iorio ML. Hand Clin. 2019 May;35(2):143-154. doi:  10.1016/j.hcl.2018.12.005. Review. PMID: 30928047

The Evolution of Breast Implants. Kaoutzanis C, Winocour J, Unger J, Gabriel A, Maxwell GP. Semin Plast Surg. 2019 Nov;33(4):217-223. doi: 10.1055/s-0039-1696985. Epub 2019 Oct 17. Review. PMID: 31632203

Current Perceptions of the Aesthetically Ideal Position and Size of the Male Nipple-Areolar Complex. Kaoutzanis C, Schneeberger SJ, Wormer B, Song H, Ye F, Al Kassis S, Winocour J, Higdon K, Perdikis G. Aesthet Surg J. 2019 Oct 14. pii: sjz276. doi: 10.1093/asj/sjz276. [Epub ahead of print] PMID: 31606742

Evolution of Bandeau Shape, Orbital Morphology, and Craniofacial Twist after Fronto-Orbital Advancement for Isolated Unilateral Coronal Synostosis: A Case-Control Study of 2-Year Outcomes. Liu MT, Khechoyan DY, Susarla SM, Skladman R, Birgfeld CB, Gruss JS, Lee A, Ellenbogen RG, Pet MA, Hopper RA. Plast Reconstr Surg. 2019 Jun;143(6):1703-1711. doi: 10.1097/PRS.0000000000005639. PMID: 31136486

The Impact of Plastic Surgery Training on Family Planning and Prenatal Health. Bourne DA, Chen W, Schilling BK, Littleton EB, Washington KM, De La Cruz C. Plast Reconstr Surg. 2019 Nov;144(5):1227-1236. doi: 10.1097/PRS.0000000000006100. PMID: 31688771


2018

Nipple-Areola Complex Reconstruction. Gougoutas AJ, Said HK, Um G, Chapin A, Mathes DW. Plast Reconstr Surg. 2018 Mar;141(3):404e-416e. doi: 10.1097/PRS.0000000000004166. PMID: 29481412

Outcomes and indications for early hand therapy after multiple concomitant elective hand procedures. Parker AM, Greyson M, Iorio ML. J Hand Ther. 2018 Jul 12. pii: S0894-1130(17)30415-5. doi: 10.1016/j.jht.2018.04.004. [Epub ahead of print] PMID: 30017409

TFCC Injuries: Meta-Analysis and Comparison of Diagnostic Imaging Modalities. Treiser MD, Crawford K, Iorio ML. J Wrist Surg. 2018 Jul;7(3):267-272. doi: 10.1055/s-0038-1629911. Epub 2018 Feb 14. PMID: 29922507

Venous Anastomoses in Anterolateral Thigh Flaps for the Lower Extremity: Vessel Selection In Lieu of Obligatory Number. Mattos D, Diamond S, Chattha AS, Riesel JN, Iorio ML. Ann Plast Surg. 2018 May 14. doi: 10.1097/ SAP.0000000000001431. [Epub ahead of print] PMID: 29762438

Outcomes Following Peripheral Nerve Transfers for Treatment of Non-Obstetric Brachial Plexus Upper-Extremity Neuropathy. Rinkinen JR, Giladi AM, Iorio ML. JBJS Rev. 2018 Apr;6(4):e1. doi: 10.2106/JBJS.RVW.17.00124. No abstract available. PMID: 29613866

Assessing the Safety and Efficacy of Regional Anesthesia for Lower Extremity Microvascular Reconstruction: Enhancing Recovery. Ruan QZ, Diamond S, Zimmer S, Iorio ML. J Reconstr Microsurg. 2018 May;34(4):293-299. doi: 10.1055/s-0037-1621726. Epub 2018 Feb 16. PMID: 29452441

Open Distal Radius Fractures: Timing and Strategies for Surgical Management. Iorio ML, Harper CM, Rozental TD. Hand Clin. 2018 Feb;34(1):33-40. doi: 10.1016/j.hcl.2017.09.004. Review. PMID: 29169595

Outcomes of Subfascial, Suprafascial, and Super-Thin Anterolateral Thigh Flaps: Tailoring Thickness without Added Morbidity. Diamond S, Seth AK, Chattha AS, Iorio ML. J Reconstr Microsurg. 2018 Mar; 34(3):176-184. doi: 10.1055/s-0037-1607426. Epub 2017 Nov 7. PMID: 29113000


2017

Re-excision rates after breast conserving surgery following the 2014 SSO-ASTRO guidelines. Heelan Gladden AA, Sams S, Gleisner A, Finlayson C, Kounalakis N, Hosokawa P, Brown R, Chong T, Mathes D, Murphy C. Am J Surg. 2017 Dec;214(6):1104-1109. doi: 10.1016/j.amjsurg.2017.08.023. Epub 2017 Sep 20. PMID: 28974314

Designing a Fibular Flow-Through Flap with a Proximal Peroneal Perforator-Free Flap for Maxillary Reconstruction. Trinh BB, French B, Khechoyan DY, Deleyiannis FW. Plast Reconstr Surg Glob Open. 2017 Nov 7; 5(11):e1543. doi: 10.1097/GOX.0000000000001543. eCollection 2017 Nov. PMID: 29263953

Median Nerve Injury after Removal of Subdermal Implantable Contraceptive. Christensen JM, Caggiano NM, Giladi AM, Iorio ML. Hand (N Y). 2017 Nov 1:1558944717744335. doi: 10.1177/1558944717744335. [Epub ahead of print]. PMID: 29185830

Lunotriquetral Ligament Reconstruction Utilizing a Palmaris Longus Autograft. Harper CM, Iorio ML. J Hand Surg Asian Pac Vol. 2017 Dec; 22(4):544-547. doi: 10.1142/S0218810417710010. PMID: 29117846

Outcomes of an Early Protocol for Dependent Conditioning in Lower Extremity Microsurgical Free Flaps. Seth AK, Diamond S, Iorio ML. J Reconstr Microsurg. 2017 Nov; 33(9):670-678. doi: 10.1055/s-0037-1604390. Epub 2017 Jul 27. No abstract available. PMID: 28750421

A Critical Appraisal of Vascularized Bone Grafting for Scaphoid Nonunion. Alluri RK, Yin C, Iorio ML, Leland H, Mack WJ, Patel K. J Wrist Surg. 2017 Aug;6(3):251-257. doi: 10.1055/s-0036-1597575. Epub 2016 Dec 8. PMID: 28725510

Reconstruction of quadriceps function with composite free tissue transfers following sarcoma resection. Walley KC, Taylor EM, Anderson M, Lozano-Calderon S, Iorio ML. J Surg Oncol. 2017 Jun; 115(7):878-882. doi: 10.1002/jso.24594. Epub 2017 Apr 13. PMID: 28407317

The Impact of Safety Regulations on the Incidence of Upper-Extremity Power Saw Injuries in the United States. Vosbikian MM, Harper CM, Byers A, Gutman A, Novack V, Iorio ML. J Hand Surg Am. 2017 Apr;42(4):296.e1-296.e10. doi: 10.1016/j.jhsa.2017.01.025. PMID: 28372641

Super-Thin and Suprafascial Anterolateral Thigh Perforator Flaps for Extremity Reconstruction. Seth AK, Iorio ML. J Reconstr Microsurg. 2017 Sep; 33(7):466-473. doi: 10.1055/s-0037-1601422. Epub 2017 Mar 31. PMID: 28363228

Vascularized Bone Grafting in Scaphoid Nonunion: A Review of Patient-Centered Outcomes. Alluri RK, Yin C, Iorio ML, Leland H, Wong J, Patel K. Hand (N Y). 2017 Mar; 12(2):127-134. doi: 10.1177/1558944716643080. Epub 2016 Jul 7. Review. PMID: 28344522

Orthopaedic Device Approval through the Premarket Approval Process: A Financial Feasibility Analysis for a Single Center. Yang BW, Iorio ML, Day CS. J Bone Joint Surg Am. 2017 Mar 15; 99(6):e26. doi: 10.2106/JBJS.16.00050. PMID: 28291189

Reversed Palmaris Longus Muscle Causing Volar Forearm Pain and Ulnar Nerve Paresthesia. Bhashyam AR, Harper CM, Iorio ML. J Hand Surg Am. 2017 Apr; 42(4):298.e1-298.e5. doi: 10.1016/ j.jhsa.2016.11.016. Epub 2016 Dec 10. PMID: 27964899

Identical Twins with Crouzon Syndrome: Eight-Year Follow-up, Genetic Considerations, and Operative Management. Lloyd MS, Trost JG, Khechoyan DY, Hollier LH Jr, Buchanan EP. Craniomaxillofac Trauma Reconstr. 2017 Dec; 10(4):286-291. doi: 10.1055/s-0036-1592091. Epub 2016 Sep 2. PMID: 29109840

Surgical Outcomes for Speech Surgery in 22q11.2 Deletion Syndrome: The Dilemma of Persistent Velopharyngeal Insufficiency after Pharyngeal Flap Operation. Wagner RD, Wolfswinkel EM, Buchanan EP, Khechoyan DY. J Craniofac Surg. 2017 Jul; 28(5):1320-1324. doi: 10.1097/SCS.0000000000003722. Review. PMID: 28582304

Hemisacrectomy with preservation of the contralateral sacral nerve roots and sacroiliac joint for pelvic neurofibrosarcoma in a 7-year-old child: case report with 2-year follow-up. Palejwala AH, Fridley JS, Garcia K, Vasudevan SA, Khechoyan D, Rednam S, Koh CJ, Jea A. J Neurosurg Pediatr. 2017 Jan; 19(1):102-107. doi: 10.3171/ 2016.7. PEDS16203. Epub 2016 Sep 30. Review. PMID: 27689246


2016

Long-term Tolerance Toward Haploidentical Vascularized Composite Allograft Transplantation in a Canine Model Using Bone Marrow or Mobilized Stem Cells. Chang J, Graves SS, Butts-Miwongtum T, Sale GE, Storb R, Mathes DW. Transplantation. 2016 Dec; 100(12):e120-e127. PMID: 27861292

Improved healthcare economic outcomes after liposomal bupivacaine administration in first-stage breast reconstruction. Miranda SG, Liu Y, Morrison SD, Sood RF, Gallagher T, Gougoutas AJ, Colohan SM, Louie O, Mathes DW, Neligan PC, Said HK. J Plast Reconstr Aesthet Surg. 2016 Oct; 69(10):1456-7. doi: 10.1016/j.bjps.2016.06.031. Epub 2016 Jul 11. No abstract available. PMID: 27475335

Comparison of Synthetic and Biologic Mesh in Ventral Hernia Repair Using Components Separation Technique. Sandvall BK, Suver DW, Said HK, Mathes DW, Neligan PC, Dellinger EP, Louie O. Ann Plast Surg. 2016 Jun;76(6):674-9. doi: 10.1097/SAP.0000000000000253. PMID: 25003419

Dermatofibrosarcoma Protruberans of the Forehead with Extensive Subclinical Spread. Benoit A, Aycock J, Milam D, Brown M. Dermatol Surg. 2016 Feb;42(2):261-4. doi: 10.1097/DSS.0000000000000604. No abstract available. PMID: 26808183

Practical Guidelines for Venous Thromboembolism Prophylaxis in Free Tissue Transfer. Ricci JA, Crawford K, Ho OA, Lee BT, Patel KM, Iorio ML. Plast Reconstr Surg. 2016 Nov;138(5):1120-1131. PMID: 27783014

Oncologic reconstruction of the hand and upper extremity: Maximizing functional outcomes. Knaus WJ, Alluri R, Bakri K, Iorio ML. J Surg Oncol. 2016 Jun; 113(8):946-54. doi: 10.1002/jso.24196. Review. PMID: 27226160

Prevention of Thumb Web Space Contracture with Multiplanar External Fixation. Harper CM, Iorio ML.
Tech Hand Up Extrem Surg. 2016 Sep; 20(3):91-5. doi: 10.1097/BTH.0000000000000123. PMID: 27203276

Separation of Thoraco-Omphalo-Ischiopagus Conjoined Twins: Surgical Planning, Management, and Outcomes. Trost JG Jr, Lin LO, Clark SJ, Khechoyan DY, Hollier LH Jr, Buchanan EP.Plast Reconstr Surg. 2016 Nov; 138(5):1064-1072. PMID: 27783004

Review of quantitative outcome analysis of cranial morphology in craniosynostosis. Lloyd MS, Buchanan EP, Khechoyan DY. J Plast Reconstr Aesthet Surg. 2016 Nov; 69(11):1464-1468. doi: 10.1016/j.bjps.2016.08.006. Epub 2016 Sep 7. Review. PMID: 27642164

Cranial Fasciitis: A Systematic Review and Diagnostic Approach to a Pediatric Scalp Mass. Wagner RD, Wang EK, Lloyd MS, Lam SK, Khechoyan DY. J Craniofac Surg. 2016 Jan;27(1):e65-71. doi: 10.1097/SCS.0000000000002230. Review. PMID: 26703041


2015

Cutaneous T-cell lymphoma with nasal necrosis. Shaum K, Aycock J. Arch Plast Surg. 2015 Mar; 42(2):259-61. doi: 10.5999/aps.2015.42.2.259. Epub 2015 Mar 16. No abstract available. PMID: 25798408

Prenatal Identification of Pierre Robin Sequence: A Review of the Literature and Look towards the Future. Kaufman MG, Cassady CI, Hyman CH, Lee W, Watcha MF, Hippard HK, Olutoye OA, Khechoyan DY, Monson LA, Buchanan EP. Fetal Diagn Ther. 2016; 39(2):81-9. doi: 10.1159/000380948. Epub 2015 May 8. Review. PMID: 25967128