Dr. Kristen Demoruelle is Associate Professor of Medicine at the University of Colorado School of Medicine in the Division of Rheumatology.
Her primary research is in rheumatoid arthritis (RA) with a focus on understanding the development of RA-related autoimmunity. She is particularly interested in understanding the mucosal site where and mechanisms by which RA-related autoimmunity initially develops prior to the onset of joint inflammation in RA and sex differences influencing this process. Her current studies focus on the lung and female genital tract as potential mucosal sites where RA-related autoimmunity may originate and aberrant neutrophil extracellular trap (NET) formation as a potential mechanism that could trigger this process. Dr. Demoruelle has published multiple manuscripts and review articles in this area. Ultimately, her research goals are to develop novel site-specific and mechanism-specific prevention strategies that abrogate RA at the site of initial immune dysregulation.