Ming-Feng Tsai, PhD
Assistant Professor

Ming-Feng Tsai, PhD

Department of Physiology and Biophysics
University of Colorado School of Medicine

RC1 North Tower, P18-7105
Mail Stop 8307
Aurora, CO 80045

E-mail: ming-feng.tsai@cuanschutz.edu


External website: http://www.tsaislab.org/

Our research focuses on molecular mechanisms and physiological functions of transporters and ion-channels, particularly Ca2+ transport proteins in mitochondria. We approach questions using a wide range of tools, including membrane-biochemistry, electrophysiology, cryo-electron microscopy, and live-cell imaging.

Please visit our external website (www.tsaislab.org) for current projects and available positions.

Chen-Wei Tsai

Chen-Wei Tsai, MD, PhD

Postdoctoral Fellow

chen-wei.tsai@ucdenver.edu

Anna Van Keuren

Anna Van Keuren

Professional Research Assistant

anna.m.vankeuren@ucdenver.edu

Jackson Haynes

Jackson Haynes

Professional Research Assistant

jackson.haynes@cuanschutz.edu

Madison Rodriguez

Madison Rodriguez

Professional Research Assistant

madison.l.rodriguez@ucdenver.edu

Tsai Lab members

Phillips CB, Tsai CW, & Tsai MF. The Conserved Aspartate Ring of MCU Mediates MICU1 Binding and Regulation in the Mitochondrial Calcium Uniporter Complex. eLife. (2019) 8: e41112.

Tsai CW & Tsai MF. Electrical Recordings of the Mitochondrial Calcium Uniporter in Xenopus Oocytes. Journal of General Physiology. (2018) 150: 1035-1043.

Tsai CW, Wu Y, Pao PC, Phillips CB, Williams C, Miller C, Ranaghan M, & Tsai MF. Proteolytic Control of the Mitochondrial Calcium Uniporter Complex. Proc Natl Acad Sci U S A. (2017) 114: 4388-4393.

Tsai MF, Phillips CB, Ranaghan M, Tsai CW, Williams C, & Miller C.
Dual Functions of a Small Regulatory Subunit in the Mitochondrial Calcium Uniporter. eLife. (2016) 5: e15545.

Tsai MF, & Miller C. Building a Temperature-Sensitive Ion Channel.
Cell. (2015) 158: 977-979

Tsai MF, Jiang D, Zhao L, Clapham D, & Miller C. Functional Reconstitution of the Mitochondrial H+/Ca2+ Exchanger Letm1.
Journal of General Physiology. (2014) 143: 67-73.

Tsai MF, McCarthy P, & Miller C. Substrate Selectivity in Glutamate-Dependent Acid Resistance in Enteric Bacteria. Proc Natl Acad Sci U S A. (2013) 110: 5898-5902.

Tsai MF, & Miller C. Substrate Selectivity in Arginine-Dependent Acid Resistance in Enteric Bacteria. Proc Natl Acad Sci U S A. (2013) 110: 5893-5897.