1. NIH R011HD119003 Gaffney (PI) 08/01/25-07/31/30
   Influence of Prosthetic Foot Stiffness on Transtibial Osseointegrated Bone-Anchored Limb Outcomes
   The primary goal of this study is to assess how prosthetic foot stiffness influences bone-implant interface loading in patients with transtibial osseointegrated bone-anchored limbs.
   Amount: $3,073,871
   Role: Co-I
2. VA RR&D I01RX005012 Stevens-Lapsley (PI) 04/01/24-03/31/28
   Multicomponent Telerehabilitation to Engage Veterans in Effective Self-Management of Complex Health Conditions 
   The primary goal of this study is to determine the effectiveness of a multicomponent telerehabilitation program for improving physical function.
   Amount: $1,999,997
   Role: Co-I
3. DoD OP220013 Christiansen & Gaffney (Co-PI) 02/01/23-01/31/27
   Transfemoral osseointegrated prosthesis limb load symmetry training (TOPLOAD)
   This randomized controlled trial will 1) determine the feasibility of a 40-week limb-load biofeedback training intervention, 2) determine if there is an intervention signal of efficacy, and 3) identify functional movement priorities for people with transfemoral osseointegrated prostheses. 
   Amount: $349,939
   Role: Co-PI
4. VA RR&D I01RX003917 Christiansen (PI) 11/01/22-10/31/26
   Walking exercise sustainability through telehealth for Veterans with lower-limb amputation
   The goal of this clinical trial is to 1) determine if telerehabilitation walking exercise self-management program produces clinically meaningful exercise sustainability compared to attention-control education after LLA and 2) evaluate potential for large-scale clinical translation of walking exercise self-management program with RE-AIM framework assessments using a mixed-methods (qualitative and quantitative) approach.
   Amount: $982,159
   Role: PI
5. NIH/NINDS 1U01NS113851 Corcos (PI) 09/25/19-07/31/26
   Study in Parkinson disease of exercise Phase III clinical trial: SPARX3
   The study goal is to establish the efficacy of high-intensity endurance exercise as first-line therapy for recently diagnosed people with Parkinson's disease (PD).
   Amount: $18,827,868 
   Role: Co-I; Site PI
6. VA RR&D I01RX003237 Christiansen (PI) 11/01/19-10/31/26
   Optimizing gait rehabilitation for Veterans with non-traumatic lower limb amputation
   The goal of this clinical trial is to compare two groups of error-manipulation intervention to a supervised walking group of Veterans with unilateral, non-traumatic transtibial amputation.
   Amount: $629,855
   Role: PI
7. VA RR&D IK2 RX004242 Mañago (PI) 10/01/22-09/30/26
   Low-load resistance training with blood flow restriction in people with Multiple Sclerosis and advanced disability: a randomized control trial
   The goal of this clinical trial is to determine between-group differences in 1) Muscle health: quadriceps strength (primary outcome) and muscle morphology (thickness and echogenicity); 2) Mobility: 30-Second Sit-to-Stand; and 3) Self-reported fatigue: Modified Fatigue Impact Scale of a blood flow restriction resistance training program for people with Multiple Sclerosis and advanced disability.
   Amount: $775,751
   Role: Primary Mentor

NIH R01NR018450 Christiansen (PI) 08/01/19-05/31/25                      
Improving health self-management using walking biobehavioral intervention for people with dysvascular lower limb amputation   
The goals of this study are to: 1) test if walking biobehavioral intervention improves physical activity and 2) evaluate the potential for clinical implementation of a walking biobehavioral intervention early after lower-limb amputation.
Amount: $1,305,250
Role: PI

NIH/NICHHD R03HD111012 Gaffney (PI) 05/15/23-04/30/25
Dynamic Bone-Implant Loading in Osseointegrated Prostheses
The goals of this study are to: 1) determine how bone-implant loading during activities of daily living differs between transfemoral and transtibial osseointegrated prostheses, 2) establish associations between clinical outcomes and bone-implant interface loading, and 3) evaluate the impact of simulated rehabilitation on bone-implant loading mechanics in patients with osseointegrated prostheses.
Amount: $288,800
Role: Co-I

NIH R01AG056585 Stevens-Lapsley (PI) 09/15/17-04/30/25
Movement Pattern Biofeedback Training Following Total Knee Arthroplasty   
The goal of this study is to determine if the addition of a novel movement pattern training program (MOVE) to contemporary, progressive rehabilitation improves movement pattern quality more than contemporary progressive rehabilitation alone (CONTROL) after total knee arthroplasty. 
Amount: $3,004,535
Role: Co-I

Davis Phinney Foundation Award Mañago (PI) 04/01/23-06/30/24
Feasibility of low-load resistance training with blood flow restriction in people with advanced disability due to Parkinson’s disease
The goal of this project is to determine the feasibility of low-load resistance training using blood flow restriction in people with PD and more advanced disability.
Amount: $99,121
Role: Co-I

VA RR&D I21RX003730 Stevens-Lapsley (PI) 07/01/21-08/31/23
Engaging Medically Complex Veterans in Tele-Rehabilitation Using a Biobehavioral Approach: A Pilot Study of Feasibly and Acceptability
The goal of this work is to assess the effectiveness of a multicomponent telerehabilitation using a two-group randomized crossover design.
Amount: $114,700 (annual award)
Role: Co-I

VA RR&D I01RX002417 Christiansen (PI) 12/1/17-05/31/23
Optimizing Physical Activity Outcomes for Veterans after Total Knee Arthroplasty
The goal of this clinical trial is to determine the efficacy of physical activity behavior-change telerehabilitation on improving physical activity after total knee arthroplasty.
Amount: $1,077,824
Role: PI

CDMRP OPORP W81XWH-17-2-0029 Disla (PI) 9/30/17-9/29/22
Women with Amputation: The Unique Needs of an Underserved Population.
The investigation is a national, online survey-based needs assessment of the physical and psychosocial needs of women with amputation.
Amount: $489,158
Role: Site PI

VA RR&D I01RX002251 Stevens-Lapsley (PI) 11/1/16-10/31/21
Advancing Rehabilitation after Total Hip Arthroplasty
The goal of this investigation is to evaluate the effectiveness of a multi-modal core stabilization program for movement pattern retraining on functional outcomes after total hip arthroplasty.
Amount: $1,099,636
Role: Co-I

Hanger Inc. Christiansen (PI) 06/01/18-05/31/21
Personalized Reference Charts for Prosthetic Rehabilitation
The goal of this project is to develop personalized reference chart use to guide prognosis and care planning for patients following lower limb amputation. This mixed-methods design study will be used to design the reference chart, implement chart use as a pilot project, and determine chart use clinical feasibility.
Amount: $30,000
Role: PI

VA RR&D I21RX002054-01A1 Christiansen (PI) 7/1/16-6/30/19    
Physical Activity Behavior Change for Older Veterans after Dysvascular Amputation
The goal of this project was to determine feasibility of a physical-activity behavior-change intervention targeting improved physical activity and reduced disability in Veterans 1-5 years following dysvascular lower limb amputation.
Amount: $194,264
Role: PI

Research Core Pilot Award (PM&R UCD) Mañago (PI) 09/01/18-08/31/19
Instrumented Motion Analysis of Hip and Trunk Movement Compensations for People with Multiple Sclerosis 
The goal of this project was to evaluate hip and trunk biomechanical compensatory strategies during functional activities in patients with multiple sclerosis.
Amount: $10,000
Role: Co-I

NIH R56AG048943 Stevens-Lapsley (PI) 09/15/15-09/14/17
Movement Pattern Training Following Total Knee Arthroplasty   
The goal of this project was to determine if the addition of a novel movement pattern training program to contemporary rehabilitation after total knee arthroplasty improved movement pattern quality and functional outcomes compared to contemporary rehabilitation alone.
Amount: $382,625
Role: Co-I

NIH K12HD055931 Mueller (PI) 09/01/13-06/30/16
Collaborative-care rehabilitation to improve functional outcomes after dysvascular amputation.
Project goals were to: 1) determine if a collaborative-care, home-based rehabilitation program improves physical function for people recovering from dysvascular transtibial amputation and 2) determine if the program improved functional activity for daily living.
Amount: $360,000
Role: Scholar, Project PI

NIH R01NS074343 Schenkman & Corcos (Co-PIs) 09/30/11-08/31/15
Exploratory Study of Different Doses of Endurance Exercise in People with Parkinson Disease
The aim of the study was to determine the futility or non-futility of conducting a Phase III randomized controlled trial to determine the effects of exercise on the progression of PD symptoms.
Amount: $2,930,000
Role: Co-I

Research Core Pilot Award (PM&R UCD) Christiansen (PI) 07/01/14-06/30/15
Movement Strategies and Physical Activity after Dysvascular Amputation.
The goals of this project were to: 1) identify compensatory movement strategies for participants with diabetes after unilateral transtibial amputation using instrumented movement analysis and 2) determine the correlations between asymmetry in movement and; gait speed, overall physical activity, and self-reported disability.
Amount: $10,000
Role: PI

The Foundation for PM&R Christiansen (PI) 11/01/12-10/31/14
Early physical function during rehabilitation following dysvascular transtibial amputation.
The goals of this project were to: 1) examine common physical function measures and 2) characterize standard of care rehabilitation for patients with diabetes following dysvascular transtibial amputation. 
Amount: $30,000
Role: PI

Foundation for PT Research Christiansen (PI) 01/01/11-06/30/13
Improving Function after Total Knee Arthroplasty with Weight-Bearing Biofeedback 
The goal of this pilot study was to: determine the effects of the weight-bearing biofeedback intervention on WB asymmetry and functional task performance. 
Amount: $40,000
Role: PI

Bob Doctor Research Award Christiansen & Stevens-Lapsley (PIs) 01/01/09-06/1/12
Limb Loading Asymmetry with Total Knee Arthroplasty
The major goals of this study were to: 1) quantify limb-loading asymmetry during functional activities before and after TKA and 2) quantify the relationship between asymmetries in limb loading, functional mobility, and muscle strength before and after TKA. 
Amount: $8,000
Role: Co-PI 

President’s Teaching Scholars Program Christiansen (PI) 09/01/11-08/31/12
Student Perceptions of Classroom Response System Use in a DPT Curriculum
The goals of this project were to: 1) determine DPT student perception of classroom response system use in the course DPTR5101-Movement Science I, and 2) determine if perceptions differ based on student learning styles, age, and sex. 
Amount: $1,500
Role: PI

NIH R01HD043770 Schenkman (PI) 04/01/08-03/31/11
Exercise, Physical Function, and Parkinson’s Disease
The aim of the study was to determine whether targeted exercise intervention improves physical functional abilities in patients with mild to moderately severe Parkinson’s disease.
Amount: $1,125,000
Role: Study Coordinator

Academic Enrichment Fund UCD Schenkman (PI) 01/01/09-12/31/11
The major goal of this funded activity was to establish an interdisciplinary movement analysis lab for use by researchers across the health sciences campus. 
Amount: $149,000
Role: Co-I