University of Colorado - Restoring Efficient Sleep After TBI (CU REST)
Colorado Multiple Institutional Review Board Number: #22-1169
Project Summary: Insomnia is a sleep condition that involves trouble with falling or staying asleep and is common after moderate-to-severe traumatic brain injury (TBI). While cognitive behavioral therapy for insomnia (CBT-I) is the gold standard for treating insomnia, access to in-person treatment can be limited by factors such as cost and lack of transportation. Computerized CBT-I programs can help individuals overcome these barriers to in-person CBT-I, but individuals with moderate-severe TBI may benefit from additional support to complete the program. We are interested in understanding whether a computerized CBT-I program, combined with individualized support from study staff, improves insomnia symptoms among individuals with moderate-to-severe TBI.
The proposed study, University of Colorado - Restoring Efficient Sleep after TBI (CU-REST), will be implemented using a randomized controlled trial design to assess the efficacy of a guided computerized CBT-I intervention for those with current insomnia symptoms and a history of moderate to severe TBI. Those allocated to the treatment arm will participate in 10 sessions of a computerized CBT-I program over the course of 6-9 weeks. Those in the control arm will receive enhanced treatment as usual (ETU).
Funding: This research study is supported by the Mindsource Brain Injury Network at the Colorado Department of Human Services under Award #23 IHEA 176151. The content of this website is solely the responsibility of the authors and does not necessarily represent the official views of the Mindsource Brain Injury Network at the Colorado Department of Human Services.
Recruitment:
You may be eligible if you are between ages 18 and 60, had a traumatic brain injury over a year ago, currently have insomnia, and have reliable access to the internet. Participants must be living in the State of Colorado.
Contact Lisa Brenner, Ph.D. at lisa.2.brenner@cuanschutz.edu
Study Team:
Lisa A. Brenner, PhD
Principal Investigator
Professor of Physical Medicine & Rehabilitation, Psychiatry, and Neurology
Lisa A. Brenner, Ph.D., is the Director of the Department of Veterans Affairs Rocky Mountain Mental Illness Research, Education, and Clinical Center (MIRECC). She is also Vice Chair of Research for the Department of Physical Medicine and Rehabilitation. Dr. Brenner is a Past President of Division 22 (Rehabilitation Psychology) of the American Psychological Association (APA) and an APA Fellow. She serves as an Associate Editor of the Journal of Head Trauma Rehabilitation. Her primary area of research interest is traumatic brain injury, co-morbid psychiatric disorders, and negative psychiatric outcomes, including suicide. Dr. Brenner has numerous peer-reviewed publications, participates on national advisory boards, and has recently co-authored a book titled: Suicide Prevention After Neurodisability: An Evidence-Informed Approach.
Nazanin Bahraini, PhD
Co-Investigator
Associate Professor of Physical Medicine and Rehabilitation and Psychiatry
Dr. Bahraini is the Director of Research at the Rocky Mountain Mental Illness Research, Education and Clinical Center (MIRECC) for Suicide Prevention and Associate Professor of Physical Medicine and Rehabilitation and Psychiatry at the University of Colorado Anschutz School of Medicine. Her work focuses on designing and evaluating system-level strategies to improve implementation of evidence-based practices in suicide prevention. Her clinical research interests include application of acceptance and commitment therapy for suicide prevention and understanding the impact of social determinants of health on suicide risk.
Jeri E. Forster, PhD
Co-Investigator
Assistant Professor of Physical Medicine and Rehabilitation
Dr. Jeri Forster, PhD, is a biostatistician, Assistant Professor in the Department of Physical Medicine and Rehabilitation (PM&R), and the Director of the Data and Statistical Core (DASC) in the VA Rocky Mountain Mental Illness, Research, Education, and Clinical Center (MIRECC) for Suicide Prevention. Dr. Forster serves on the Board of Governors for the VA/DoD Mortality Data Repository and on the Editorial Board for the Journal of Head Trauma Rehabilitation. Her primary areas of research collaboration include suicide, traumatic brain injury, co-morbid psychiatric disorders, physical therapy for older and medically complex individuals.
Adam R. Kinney, PhD
Co-Investigator
Assistant Professor of Physical Medicine and Rehabilitation
Dr. Kinney is an Occupational Therapist and Investigator with the Rocky Mountain Mental Illness Research Education and Clinical Center (MIRECC), and an Assistant Professor of Physical Medicine and Rehabilitation (PM&R) at the University of Colorado, Anschutz Medical Campus. His primary area of research focuses on promoting Veterans’ receipt of evidence-based treatment for sleep conditions following traumatic brain injury. He is also interested in understanding how multi-level determinants (e.g., person-, provider-, system-, or societal-level) influence service delivery and positive outcomes among individuals with a history of traumatic brain injury and other potentially disabling conditions.
Christie Machan, LCSW
Study Clinician
Licensed Clinical Social Worker
Christie Machan is a Licensed Clinical Social Worker and Study Clinician with the Rocky Mountain Mental Illness Research Education and Clinical Center (MIRECC). Her work and clinical areas of interest include the reduction of suicide risk and enhancement of recovery from brain injuries and trauma with evidence based interventions that enhance healthy social supports for impacted individuals.
Molly E. Penzenik, MPH
Data Analyst
Instructor, Department of Physical Medicine and Rehabilitation
Molly Penzenik is a health science specialist in the Rocky Mountain Mental Illness Research Education and Clinical Center (MIRECC) Data and Statistical Core. She completed an MPH in biostatistics at West Virginia University School of Public Health. She has supported program evaluations and numerous research studies focusing on mental health and suicide prevention, including traumatic brain injury, PTSD, upstream suicide prevention interventions, and complementary and alternative medicine. She has extensive experience with online data collection methods.
Daniel J. Reis, PhD
Co-Investigator
Instructor/Fellow, Department of Psychiatry
Daniel Reis is Clinical Research Psychologist at the Rocky Mountain Mental Illness Research Education and Clinical Center (MIRECC) and Instructor/Fellow in the Department of Psychiatry at the University of Colorado, Anschutz Medical Campus. His research is focused on the role of circadian disruption in suicide and up-stream risk factors, such as sleep and mood disorders. He is also interested in how digital technology, such as high-resolution activity and light monitoring, can be used to enhance circadian-targeted interventions, or “chronotherapies”, like bright light therapy.
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Emerald G. Saldyt
Research Coordinator
Professional Research Assistant
Emerald Saldyt is a professional research assistant at the Rocky Mountain Mental Illness Research Education and Clinical Center (MIRECC). She graduated summa cum laude from the University of Colorado Denver with a Bachelor of Science in psychology and a minor in neuroscience. Her multidisciplinary research background includes evaluating program efficacy and understanding individual differences in affective reactivity, prosocial behavior, mindfulness, depersonalization, and emotional well-being.
Molly Sullan, PhD
Study Clinician
Assistant Professor of Physical Medicine and RehabilitationMolly Sullan is a Clinical Research Psychologist within the Rocky Mountain Mental Illness Research Education and Clinical Center (MIRECC), and an Assistant Professor of Physical Medicine and Rehabilitation (PM&R) at the University of Colorado, Anschutz Medical Campus. Her primary area of research focuses on understanding the relationship between traumatic brain injury and post-traumatic sleep difficulties. This includes the relationship between post-traumatic sleep difficulties and differences in long-term cognitive, psychological, and physiological recovery.
