Welcome to Adams Lab

Our research focuses on the study of bone and joint health in the context of genetic regulation, aging, and injury repair.  We conduct Genome Wide Association Studies to identify genes involved in regulating the variable anabolic response of bone to intermittent parathyroid hormone (PTH), and to identify genes involved in the regulation of bone strength as well as genetic interactions with aging and dysbiosis of gut flora.  These studies seek to elucidate new targets for the development of candidate drugs for treating bone disease, and to provide insight for clinical decisions in the treatment of osteoporosis.  Additional research focuses on molecular mechanisms involved in fracture repair, and the role of changes in joint loading patterns leading to disruption of articular chondrocyte homeostasis and subsequent tissue degradation associated with osteoarthritis.