Skip to content
University of Colorado Anschutz Medical Campus CU Anschutz
  • Webmail
  • UCD Access
  • Canvas
  • Quick Links
 

Tools & Resources

  • Events Calendar
  • Newsroom
  • Strauss Health Sciences Library
  • Department A-Z Directory
  • Campus Directory
  • Leadership
  • Faculty & Staff Resources
  • Supporter & Alumni Resources
  • Student Resources
  • Campus Map
  • University Policies
  • Give Now

CU Campuses

  • CU Anschutz Medical Campus
  • CU Boulder
  • CU Colorado Springs
  • CU Denver
  • CU System
  • CU Online

CU Anschutz Medical Campus

  • School of Dental Medicine
  • Graduate School
  • School of Medicine
  • College of Nursing
  • Skaggs School of Pharmacy and Pharmaceutical Sciences
  • Colorado School of Public Health

Division of Medical Oncology

School of Medicine

  • Home
  • Leadership
    • Division Head | Wells Messersmith, MD, FACP
    • Deputy Division Head | Virginia Borges, MD, MMSc
  • Research
  • Cancer Care
    • CARE Clinic
    • Clinical Trials
    • Find a Provider
    • Satellite Locations
  • Education
  • Giving
  • Newsroom
  • Division Resources
  • Division Directory
    • Clinical & Research Faculty
    • Research Services Personnel
    • Administrative Staff
University Quick Links
  • Home
  • Research
  • Cutaneous Cancer
  • SciOmics Research Lab

SCIOMICS RESEARCH LAB

Research Focus

The SciOmics (Single-Cell Integrated Omics) Lab uses high dimension, multi-omic approaches combined with data science to discover and characterize biomarkers associated with cancer patient outcomes.  Our lab emphasizes the use of multidisciplinary and creative approaches to dissect the complexities of anti-tumor immune responses and immunotherapy resistance mechanisms, with the goal of translating our findings back into the clinic.  

Current Research Project Foci: 

The roles of STAT/cytokine signaling pathways in checkpoint immunotherapy.
The use of HDAC inhibitors and other epigenetic modifying agents in combination with immunotherapies.
Development of new data analysis pipelines and tools.
A novel population of T-cells expressing ectoenzymes associated with checkpoint immunotherapy resistance.


David Woods, PhD

Principle Investigator

Carol Amato, MS

Research Services Senior Professional

Ann Strange, MBA

Research Services Senior Professional

Brian Thompson, PhD

Postdoctoral Fellow

Jonathan Hester-McCullough, BA

Research Services Professional

Selected Publications

Ichikawa J, Yoshida T, Isser A, Laino AS, Vassallo M, Woods D, Kim S, Oelke M, Jones K, Schneck JP, Weber JS. Rapid Expansion of Highly Functional Antigen-Specific T Cells from Patients with Melanoma by Nanoscale Artificial Antigen-Presenting Cells. Clin Cancer Res. 2020 Jul 1;26(13):3384-3396. doi: 10.1158/1078-0432.CCR-19-3487. Epub 2020 Apr 2. PMID: 32241816.

Woods DM, Laino AS, Winters A, Alexandre J, Freeman D, Rao V, Adavani SS, Weber JS, Chattopadhyay PK. Nivolumab and ipilimumab are associated with distinct immune landscape changes and response-associated immunophenotypes. JCI Insight. 2020 Jun 4;5(11):e137066. doi: 10.1172/jci.insight.137066. PMID: 32303612. 

Yoshida, T., Ichikawa, J., Giuroiu, I., Laino, A. S., Hao, Y., Krogsgaard, M., Vassallo, M., Woods, D. M., Stephen Hodi, F., & Weber, J. (2020). C reactive protein impairs adaptive immunity in immune cells of patients with melanoma. Journal for immunotherapy of cancer, 8(1), e000234. https://doi.org/10.1136/jitc-2019-000234.  PMID: 204799.

Laino, A. S., Woods, D., Vassallo, M., Qian, X., Tang, H., Wind-Rotolo, M., & Weber, J. (2020). Serum interleukin-6 and C-reactive protein are associated with survival in melanoma patients receiving immune checkpoint inhibition. Journal for immunotherapy of cancer, 8(1), e000842. https://doi.org/10.1136/jitc-2020-000842. PMID: 32581042.

Laino AS, Betts BC, Veerapathran A, Dolgalev I, Sarnaik A, Quayle SN, Jones SS, Weber JS, Woods DM. HDAC6 selective inhibition of melanoma patient T-cells augments anti-tumor characteristics. J Immunother Cancer. 2019 Feb 6;7(1):33. doi: 10.1186/s40425-019-0517-0. PMID: 30728070.

Complete List of Publications

Medical Oncology (SOM)

CU Anschutz

Research I South

12801 East 17th Avenue

8122

Aurora, CO 80045


720-848-0300

Facebook Twitter
School
  • School of Medicine Home
  • Find a Doctor
  • Find a Researcher
  • Departments
  • Contact Us
  • Donate
  • School Profiles
General
  • Affiliate/Partner Hospitals
  • CU Medicine
  • A-Z Index
  • Directory
  • Map and Parking
  • Webmail
Students
  • Apply Now
  • Alumni
  • Canvas
  • Health Science Library
  • Student Life
  • Colorado Springs Branch
  • Contact Us
  • Website Feedback
  • CU System
  • Privacy Policy
  • Terms of Use
  • Accessibility
  • Accreditation
  • Employment
  • Give Now
 

© 2023 The Regents of the University of Colorado, a body corporate. All rights reserved.

Accredited by the Higher Learning Commission. All trademarks are registered property of the University. Used by permission only.

CMS Login

Webmail

UCD Access

Canvas

Opens in a new window Opens document in a new window