Information for Health Care Providers

Colorado Department of Public Health & Environment (CDPHE): COVID-19 Treatments. CDPHE provides current information for health care providers who want to prescribe monoclonal antibody treatment for patients.

Recommended Resource: Federal Response to COVID-19: Monoclonal Antibody Clinical Implementation Guide.

This HHS Playbook resource, recently updated, provides outpatient administration guidance for healthcare providers, including intravenous or subcutaneous treatment. This also covers COVID-19 treatment and post-exposure prophylaxis.


Here are webinars brought to you by ECHO Colorado, mAbColorado, and the Colorado Department of Public Health and Environment.

September, 1, 2021: This webinar will cover data around current monoclonal antibody use in Colorado

September, 1, 2021: This 8-minute video includes a frontline example from a long-term care facility in Colorado

Referral Checklist for monoclonal antibody referral

A step-by-step list to guide you through the process of patient referral for COVID-19 monoclonal antibody treatment.


Counseling Patients On mAb Treatment

This downloadable flyer provides sample language for talking with patients about COVID-19 monoclonal antibody treatment.




Eligibility, Treatment Options, Finding Treatment, Coverage & Payment


Colorado Department of Public Health & Environment (CDPHE): COVID-19 Treatments. Overview instructions for health care providers who want to prescribe monoclonal antibody treatment for patients.

Determine Patient Eligibility

**As of May 14, 2021, there is expanded eligibility for monoclonal antibody treatment.

Patients who meet the following criteria or demonstrate the following symptoms may be eligible to receive COVID-19 monoclonal antibody therapeutics:

  • Not hospitalized or on oxygen due to COVID-19.
  • High risk of developing severe disease and hospitalization.
  • Able to receive treatment within 10 days of developing symptoms.

Patients who have been vaccinated may receive monoclonal antibody treatment.

Current eligibility for COVID-19 positive individuals, as of June 2021:mAb Eligibility infographic 21-927


Discuss Treatment Options

NIH COVID-19 Treatment Guidelines for monoclonal antibodies provide clinicians with guidance on how to care for patients with COVID-19. Because clinical information about the optimal management of COVID-19 is evolving quickly, these guidelines are updated frequently.

Monoclonal antibodies have been shown to reduce COVID-19-related hospitalizations and deaths from any cause. See this NIH table of clinical trial data.

Shared decision making should include information about the FDA emergency use authorization. For more information about the limits of authorized use for these monoclonal antibody therapies, including information about viral variants and antiviral resistance, review the following (Updated May 14, 2021):

         Spanish (324KB)

         Spanish (131KB) (updated May 14, 2021)

Click for updated FDA information about COVID-19 Emergency Use Authorizations from the U.S. Food & Drug Administration.

Find a Treatment Center 

Use the CDPHE COVID-19 Monoclonal Antibody Connector tool to send a referral to an infusion center chosen with input from your patient. Provide the patient with the infusion center phone number to call and schedule a same- or next-day appointment.

Colorado Infusion Center Map: Generated by CDPHE, this map can be used to find the nearest infusion center where you can receive mAbs. 

National Infusion Center Association: This is the most comprehensive database of sites administering COVID-19 antibody treatments currently available. NICA works closely with the distributor to add new treatment locations.

More information available: COMBATCOVID U.S. Department of Health & Human Services Office of the Assistant Secretary for Preparedness and Response (ASPR). Call to get more information about monoclonal antibody treatments or identify an infusion site near you call the mAb call center:

English: 1-877-332-6585
Spanish: 1-877-366-0310

Coverage and Payment Information Monoclonal Antibody COVID-19 Infusion - Regularly updated information on monoclonal antibody therapies, including updates about viral variants, Medicare coverage, and coding, payment and billing.

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    This project is funded by a grant from the National Institutes of Health (NIH) and National Center for Advancing Translational Sciences (NCATS) (award number UL1-TR002535-03S3).