As many as 8 in 10 people with Down syndrome develop Alzheimer’s disease.

The Trial-Ready Cohort-Down Syndrome, or TRC-DS, matches people with Down syndrome to clinical trials targeting Down-syndrome related Alzheimer’s disease. It is a national clinical study, and the Linda Crnic Institute for Down Syndrome is a qualified participation site near Denver, Colorado.

TRC-DS needs 120 healthy people between the ages of 35 and 55 with Down syndrome.

Because Alzheimer’s disease affects people with Down syndrome at a much earlier age than the general population, researchers are looking for volunteers 35 to 55 years old to participate in research.

Man with Down syndrome wearing glasses and smiling.

According to the National Institutes of Health: Alzheimer’s disease is an irreversible brain disorder that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks.

People with Down syndrome have an increased risk of death from Alzheimer’s disease, and by age 40, virtually all people with Down syndrome have a buildup of plaques in the brain, called amyloid, that leads to Alzheimer’s disease.

Now is the time to bring the latest discoveries in the Alzheimer’s field to the Down syndrome population!

Learn More About TRC-DS

Researchers want to deliver the most promising Alzheimer’s treatments to people with Down syndrome, but they cannot do it alone.

By creating a community of people who are interested in learning about research opportunities and are ready and willing to participate, we hope to recruit participants for future clinical trials more quickly.

If research can uncover ways to slow or prevent the progression of Alzheimer’s disease in people with Down syndrome, it may also teach scientists how to target Alzheimer’s disease in the general population.

TRC-DS needs 120 healthy people between the ages of 35 and 55 with Down syndrome.

Because Alzheimer’s disease affects people with Down syndrome at a much earlier age than the general population, researchers are looking for volunteers between the ages of 35 and 55 to participate in research.

Volunteers must visit the Crnic Institute at the University of Colorado Anschutz Medical Campus in Aurora, CO once every 16 months for physical exams and other medical tests (blood draw, brain imaging scans like PET or MRI) and memory skills assessments to measure changes in their brain health and function.

You can also call us at (303)724-0491.

As many as 8 in 10 people with Down syndrome develop Alzheimer’s disease.

The Trial-Ready Cohort-Down Syndrome, or TRC-DS, matches people with Down syndrome to clinical trials targeting Down-syndrome related Alzheimer’s disease. It is a national clinical study, and the Linda Crnic Institute for Down Syndrome is a qualified participation site near Denver, Colorado.

TRC-DS needs 120 healthy people between the ages of 35 and 55 with Down syndrome.

Because Alzheimer’s disease affects people with Down syndrome at a much earlier age than the general population, researchers are looking for volunteers 35 to 55 years old to participate in research.

According to the National Institutes of Health: Alzheimer’s disease is an irreversible brain disorder that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks.

People with Down syndrome have an increased risk of death from Alzheimer’s disease, and by age 40, virtually all people with Down syndrome have a buildup of plaques in the brain, called amyloid, that leads to Alzheimer’s disease.

Now is the time to bring the latest discoveries in the Alzheimer’s field to the Down syndrome population!

Learn More About TRC-DS

Why volunteer?

Who can participate?

What is involved?

How do I join?

You can also call us at (303)724-0491.