CFReT Fall Symposium 2019

CFReT Most Recent Publications

Arterioscler Thromb Vasc Biol

"PTEN (Phosphatase and Tensin Homolog) Protects Against Ang II (Angiotensin II)-Induced Pathological Vascular Fibrosis and Remodeling-Brief Report."

Lu S, Strand KA, Mutryn MF, Tucker RM, Jolly AJ, Furgeson SB, Moulton KS, Nemenoff RA, Weiser-Evans MCM

PTEN (Phosphatase and Tensin Homolog) Protects Against Ang II (Angiotensin II)-Induced Pathological Vascular Fibrosis and Remodeling

Circulation: Heart Failure

"Coronary Artery Remodeling and Fibrosis With Continuous-Flow Left Ventricular Assist Device Support"

Amrut V. Ambardekar, Mary C.M. Weiser-Evans, Marcella Li, Suneet N. Purohit, Muhammad Aftab, T. Brett Reece, Karen S. Moulton​

Full text: http://circheartfailure.ahajournals.org/content/11/5/e004491.long​

Science Translational Medicine  

"Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism"

Mark Y. Jeong, Ying H. Lin, Sara A. Wennersten, Kimberly M. Demos-Davies, Maria A. Cavasin, Jennifer H. Mahaffey, Valmen Monzani, Chandrasekhar Saripalli, Paolo Mascagni, T. Brett Reece, Amrut V. Ambardekar, Henk L. Granzier, Charles A. Dinarello and Timothy A. McKinsey

 Full text: http://stm.sciencemag.org/cgi/content/full/10/427/eaao0144?ijkey=Y88ZIj/pQuXFY&keytype=ref&siteid=scitransmed

The Journal of Clinical Investigation

"PTEN deficiency promotes pathological vascular remodeling of human coronary arteries"

Karen S. Moulton, Marcella Li, Keith Strand, Shawna Burgett, Penn McClatchey, Rebecca Tucker, Seth B. Furgeson, Sizhao Lu, Bruce Kirkpatrick, Joseph C. Cleveland, Raphael A. Nemenoff, Amrut V. Ambardekar,and Mary C.M. Weiser-Evans

Full text: https://insight.jci.org/articles/view/97228

Circulation Research

"Differentiated Smooth Muscle Cells Generate a Subpopulation of Resident Vascular

Progenitor Cells in the Adventitia Regulated by KLF4", 

Mark W. Majesky, Henrick Horita, Allison Ostriker, Sizhao Lu, Jenna N. Regan, Ashim Bagchi, 

Xiu Rong Dong, Joanna Poczobutt, Raphael A. Nemenoff, and Mary C.M. Weiser-Evans (2016) 

Nature Communications​

"Nuclear PTEN functions as an essential regulator of SRF-dependent transcription to control smooth 

muscle differentiation", 

Henrick Horita, Christina L. Wysoczynski, Lori A. Walker, Karen S. Moulton, Marcella Li, 

Allison Ostriker, Rebecca Tucker, Timothy A. McKinsey, Mair E.A. Churchill, Raphael A. Nemenoff, 

& Mary C.M. Weiser-Evans (2016) 

Biomed Opt Express

"Characterizing fibrosis in UUO mice model using multiparametric analysis of phasor distributionfrom FILM images.", Ranjit S., Levi, M., Furgeson, S., Gratton, E., (2016) 

Kidney International

"Label-free fluorescence lifetime and second harmonic generation imaging microscopy improves quantification of experimental renal fibrosis",

Ranjit, S., Dobrinskikh, E., Montford, J., Dvornikov, A., Lehman, A., Orlicky, DJ., Nemenoff, R., Gratton, E., Levi, M., Furgeson, S., (2016) 

J. Mol. Cell Cardiology

"Epigenetic regulation of cardiac fibrosis" Stratton, MS., McKinsey TA., (2016)