Canvas access has been restored for our users, but the service reliability remains uncertain. Due to recent events, Canvas has had intermittent outages which are at the discretion of the vendor and may occur during a final exam. Faculty and staff may continue to use Canvas, but we strongly advise faculty and students to prepare a contingency plan for turning in assignments and final exams in the event Canvas access becomes unavailable again.
Instructure, the company that owns Canvas, has provided an FAQ about the incident, which may not answer all your questions. We will share more information if it becomes available.
Dr Cheruiyot Harvey’s lab aims to understand how stressors in the pancreatic beta-cell microenvironment interact with mRNA translation quality control mechanisms to trigger autoimmunity in Type 1 diabetes (T1D) and drive disease progression in Type 2 Diabetes (T2D). Ultimately their mission is to develop novel approaches to protect beta-cells from immune destruction, prevent progressive beta-cell failure in diabetes, and improve functionality of ex vivo beta-cells for cell replacement therapies. To uncover these mechanisms, they integrate biochemical and multi-omics tools—including reporter assays, ribosome profiling, sequencing, proteomics, and CRISPR/Cas9 screening—using complementary models ranging from cell lines and primary human/mouse/rat islets to stem cell–derived beta-cells and in vivo systems.
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